MELA DERM SERUM

Alpha-Arbutin primarily works by inhibiting tyrosinase, a key enzyme responsible for melanin production. It competitively blocks the enzyme's active site, preventing the conversion of L-tyrosine to L-DOPA, an early step in melanin synthesis. This mechanism helps reduce the formation of melanin pigments, leading to a lighter and more even skin tone. Kojic acid, on the other hand, acts through multiple mechanisms. It chelates copper ions, which are essential for the activity of tyrosinase, thereby inhibiting the enzyme's function. Additionally, kojic acid can directly scavenge free radicals and exhibit antioxidant properties, further contributing to its skin-lightening effects. By interfering with different stages of melanogenesis, both Alpha-Arbutin and Kojic acid effectively reduce melanin production and promote a more uniform complexion.

Alpha-Arbutin, Kojic acid 0.035

Tyrosinase inhibitors

Serum

The following are the uses of Alpha-Arbutin, Kojic acid 0.035 Liquid:

• Used for skin brightening and evening out skin tone
• Used to reduce the appearance of dark spots, age spots, and hyperpigmentation
• Used to inhibit melanin production, resulting in a lighter and more uniform complexion
• Used for improving overall skin clarity and radiance
• Used to enhance the effectiveness of other skincare products when used together
• Used for a gentle and effective approach to achieving brighter, more radiant skin
• Used as an alternative to harsher skin lightening agents
• Used in skincare formulations to promote a clear and luminous complexion

In the case of an overdose of Alpha-Arbutin or Kojic acid 0.035 Liquid, several symptoms may occur, including skin irritation, redness, and potential gastrointestinal discomfort. It is important to seek medical advice and consult a healthcare professional who can provide guidance on managing the specific symptoms. They will be able to offer tailored advice and ensure appropriate treatment for any adverse effects experienced.

In the case of a missed dose of Alpha-Arbutin, it is recommended to apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular application schedule. For Kojic acid 0.035 Liquid, if a dose is missed, apply it as soon as possible, but avoid applying it if it's almost time for the next dose. Instead, continue with the regular dosing schedule and do not double the dose to make up for the missed one.

To use Alpha-Arbutin and Kojic acid 0.035 liquid, apply a thin layer directly to the affected skin area once or twice daily, or as directed by your dermatologist, after cleansing and toning your skin.

Following are the conditions or situations when Alpha-Arbutin and Kojic acid 0.035 Liquid should not be used:

• Avoid using if you have a known allergy or sensitivity to Alpha-Arbutin or Kojic acid.
• Do not use on skin that is broken, irritated, or severely inflamed.
• Not recommended for individuals with a history of skin conditions like eczema or dermatitis.
• Do not use on children's skin without medical supervision.
• Avoid using on skin that will be exposed to direct sunlight, as it may increase sensitivity.
• Discontinue use if you experience severe skin reactions or side effects.
• Not suitable for individuals who are pregnant or breastfeeding, unless advised by a healthcare professional.
• Do not use if the product is past its expiration date or shows signs of deterioration.

The side effects of Alpha-Arbutin and Kojic acid 0.035 Liquid may include:

• Skin irritation or redness at the application site
• Itching or stinging sensation
• Dryness or flakiness of the skin
• Increased sensitivity to sunlight (photosensitivity)
• Darkening or discoloration of the skin (in rare cases)
• Allergic reactions, such as rash, hives, or itching
• Mild burning or tingling sensation

Following are the precautions and warnings for Alpha-Arbutin, Kojic acid 0.035 Liquid:

• Avoid contact with eyes and mucous membranes; in case of accidental contact, rinse thoroughly with water.
• This product is for external use only; do not ingest or apply to open wounds.
• Perform a patch test on a small area of skin before using to ensure no allergic reactions occur.
• Discontinue use if skin irritation, redness, or itching develops, and consult a healthcare professional.
• Keep out of reach of children and pets.
• Store in a cool, dry place, away from direct sunlight and heat sources.
• Consult a dermatologist or healthcare provider for personalized advice and to ensure this product is suitable for your specific skin concerns.

Following are the drug interactions for Alpha-Arbutin, Kojic acid 0.035 Liquid:

• Alpha-Arbutin may increase skin sensitivity when exposed to sunlight, so avoid using photosensitizing drugs simultaneously.
• Kojic acid can interact with anti-diabetic medications, potentially causing hypoglycemia, and close monitoring of blood glucose levels is necessary.
• Avoid using with other skin-lightening agents, as it may increase the risk of skin irritation and hyperpigmentation.
• Topical vitamin C products can enhance the effectiveness of Kojic acid but may also increase skin sensitivity.
• The combination of Alpha-Arbutin and hydroquinone should be avoided due to potential skin discoloration and increased sensitivity.
• Retinoids, when used with Kojic acid, can cause enhanced skin exfoliation but may also lead to increased skin sensitivity.
• Some acne medications containing benzoyl peroxide can react with Kojic acid, reducing its effectiveness and potentially causing skin dryness.

Following are the food interactions for Alpha-Arbutin and Kojic Acid:

• Citrus fruits like oranges, lemons, and grapefruits may increase skin sensitivity when combined with Alpha-Arbutin and Kojic Acid, potentially causing irritation.
• Avoid foods rich in vitamin C supplements during treatment as they can enhance the effects of Kojic Acid, leading to increased skin sensitivity.
• Kojic Acid may react with fermented foods like yogurt, kimchi, and sauerkraut, reducing its effectiveness.
• Dairy products might interfere with Alpha-Arbutin's absorption, so consider spacing out their consumption.
• Alpha-Arbutin's efficacy could be reduced by soy-based foods and soy milk due to their potential interaction.
• Limit sun exposure and avoid excessive UV rays as Kojic Acid can make skin more photosensitive.
• Processed and sugary foods may counteract the benefits of Alpha-Arbutin and Kojic Acid, hindering skin improvement.
• Stay hydrated by drinking plenty of water to support the skin's natural processes during treatment.

Alpha-Arbutin and Kojic Acid 0.035% Liquid should be stored in a controlled environment, preferably in a cool, dry place away from direct sunlight and heat sources. The liquid should be kept in its original container, tightly sealed to maintain its integrity and prevent contamination. It is crucial to avoid extreme temperatures, as they can impact the stability of the product. Always check the expiration date before use and dispose of any unused or outdated liquid responsibly. Do not dispose of it through household waste or pour it down the drain; instead, follow local guidelines or consult a healthcare professional for appropriate disposal methods. Keep this liquid away from children to prevent accidental exposure.

Following are the quick tips for Alpha-Arbutin and Kojic Acid 0.035 Liquid:

• Consult a dermatologist before use for personalized advice.
• Apply a small amount as directed, focusing on affected areas.
• Use sunscreen daily to protect treated skin from sun sensitivity.
• Avoid contact with eyes and mucous membranes.
• Discontinue use if irritation or redness occurs.
• Store in a cool, dry place, away from direct sunlight.
• Do not use if you are allergic to any of the ingredients.
• Always perform a patch test before applying to a larger area.