Mesan (500mg) 4 Tablets

Niacinamide, also known as nicotinamide, is a water-soluble amide form of vitamin B3. When administered orally, it serves as a vital precursor for the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). These coenzymes play critical roles in various biological processes, particularly energy metabolism and DNA repair. Niacinamide's primary mechanism of action involves enhancing the synthesis of these coenzymes, which, in turn, support numerous enzymatic reactions essential for cellular function and overall health. By promoting the production of NAD and NADP, niacinamide contributes to energy production, cellular signaling, and the maintenance of genomic stability, making it a fundamental component in supporting cellular metabolism and overall physiological well-being.

Vitamin B3 derivative.

Tablet

The following are the uses of Niacinamide Tablet:

• Used for improving skin health and reducing the appearance of blemishes and acne.
• Used for supporting cellular energy production and metabolism.
• Used for promoting brain function and cognitive health.
• Used for managing high cholesterol levels and improving cardiovascular health.
• Used for treating niacin deficiency and related conditions.
• Used for reducing inflammation and easing joint pain in arthritis.
• Used for supporting healthy aging and cellular longevity.
• Used for enhancing exercise performance and recovery.

In the case of an overdose of Niacinamide Tablets, individuals may experience symptoms such as flushing, itching, nausea, and vomiting. Skin reactions like rashes or hives can also occur. If you suspect an overdose, it is essential to seek medical advice promptly. Treatment may involve managing symptoms and providing supportive care. Always consult a healthcare professional for specific guidance regarding any suspected overdose, as they can provide personalized recommendations based on individual circumstances.

In the case of a missed dose of Niacinamide Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To take the Niacinamide Tablet, swallow the tablet whole with a full glass of water, preferably during or after a meal, as directed by your healthcare professional, typically once or twice daily.

Here are the conditions or situations when Niacinamide Tablet should not be taken:

• Avoid using Niacinamide if you have a known allergy or sensitivity to Niacinamide or any other B-vitamin supplements.
• Not suitable for individuals with severe liver disease, as it can worsen liver function.
• Should not be used in individuals with active stomach ulcers or bleeding disorders, as it may increase the risk of bleeding.
• Contraindicated in patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency.
• Not recommended for individuals with a history of gout, as it may increase uric acid levels.
• Avoid using if you have a history of heartburn or gastroesophageal reflux disease (GERD), as it may exacerbate these conditions.
• Niacinamide should not be taken if you are already using other medications or supplements that contain Niacin or Niacinamide to avoid excessive doses.
• Do not use if you have a history of kidney stones, as it may increase the risk of stone formation.

The side effects of Niacinamide Tablet may include:

• Skin flushing (redness or warmth)
• Itching or skin rash
• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Headache
• Dizziness
• Dry skin or skin peeling

Here are the precautions and warnings for Niacinamide Tablets:

• Niacinamide tablets should be used with caution in individuals with a history of liver or kidney disease, as it may require dosage adjustments.
• Not recommended for individuals with a known allergy to niacinamide or similar substances.
• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of liver-related side effects.
• May cause dizziness; patients should exercise caution when performing activities that require alertness, such as driving or operating machinery.
• Not suitable for children unless prescribed by a healthcare professional.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking niacinamide.
• Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
• Discontinue use and seek medical attention if you experience any severe or persistent side effects.

Following are the drug interactions for Niacinamide Tablet:

• May decrease the effectiveness of antihypertensive drugs like beta-blockers and diuretics, requiring close monitoring of blood pressure.
• Can interact with diabetes medications, including insulin and oral hypoglycemic agents, potentially affecting blood sugar control.
• Niacinamide may increase the risk of bleeding when taken with anticoagulants or antiplatelet drugs, such as warfarin or clopidogrel.
• The effect of anti-inflammatory medications, including NSAIDs and corticosteroids, may be reduced by Niacinamide.
• Probenecid, a medication used to treat gout, can increase the blood levels of Niacinamide, potentially requiring dosage adjustments.
• Niacinamide may enhance the skin sensitivity to sunlight when used with photosensitizing drugs, such as certain antibiotics and retinoids.
• Concomitant use with carbamazepine may increase the risk of adverse effects due to carbamazepine toxicity.

Following are the food interactions for Niacinamide Tablets:

• Niacinamide may interact with high-protein foods, as protein-rich diets can increase the excretion of niacin, potentially reducing the effectiveness of the medication.
• Alcohol intake should be limited as it can interfere with the absorption of Niacinamide and increase the risk of liver-related side effects.
• Avoid consuming large amounts of hot beverages like coffee or tea, as they may interfere with the absorption of the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of many drugs, potentially altering the effectiveness of Niacinamide.
• Dairy products like milk and yogurt can affect the absorption of Niacinamide, so it's best to separate their consumption by a few hours.
• Foods rich in vitamin B3, such as whole grains, nuts, and legumes, can complement the effects of Niacinamide, but excessive intake should be monitored to prevent potential side effects.
• Avoid excessive sugar intake, as high blood sugar levels can reduce the effectiveness of Niacinamide in managing certain conditions.
• Stay well-hydrated, especially when taking Niacinamide, as adequate water intake supports overall health and the medication's effectiveness.

Niacinamide Tablets should be stored in a cool, dry area, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent exposure to external contaminants. Avoid storing them in bathrooms or areas with high humidity, as this can impact their effectiveness. Regularly check the expiration date, and dispose of any expired or unused tablets promptly. Proper disposal methods are recommended, such as returning them to a pharmacy or a healthcare facility, rather than flushing them down the toilet or pouring them into drains. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Niacinamide Tablets:

• Consult your doctor before use, especially if you have a medical condition or are taking other medications.
• Take the tablets as directed by your healthcare provider, typically with a meal or as instructed.
• Swallow the tablets whole with a full glass of water for better absorption.
• Maintain a consistent dosing schedule to ensure maximum benefits.
• Do not crush or chew the tablets unless advised by your doctor.
• Inform your doctor if you experience any adverse effects or allergic reactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.