Mexair (0.3mg/ml) 60ml Syrup

Terbutaline, the active ingredient in Terbutaline Syrup/Suspension, primarily acts as a selective beta-2 adrenergic receptor agonist. When administered, it binds to beta-2 adrenergic receptors in the smooth muscle cells of the airways. This binding triggers a series of intracellular events, leading to the activation of adenylate cyclase, which in turn increases the production of cyclic adenosine monophosphate (cAMP). Elevated cAMP levels cause smooth muscle relaxation in the airways, resulting in bronchodilation. By relaxing the smooth muscles surrounding the airways, Terbutaline effectively relieves bronchoconstriction, reduces airway resistance, and improves airflow to the lungs. This mechanism of action makes Terbutaline a valuable medication for managing bronchospasm and related respiratory conditions.

Bronchodilator.

Suspension

The following are the uses of Terbutaline Syrup/Suspension:

• Used for preventing and treating wheezing and shortness of breath caused by breathing problems like asthma.
• Used for relaxing the airways, making breathing easier, and reducing coughing and wheezing.
• Used for managing asthma symptoms, especially during asthma attacks or when other medications are not providing relief.
• Used for preventing asthma symptoms triggered by exercise or physical activity.
• Used for long-term management of asthma, often in combination with other medications.
• Used for treating chronic obstructive pulmonary disease (COPD) in some cases, to improve breathing and reduce exacerbations.
• Used for providing quick relief during sudden asthma episodes, offering temporary relief of symptoms.

To be taken as per doctor's prescription

In the case of an overdose of Terbutaline Syrup/Suspension, the severity of symptoms can vary depending on the amount ingested. Common signs may include rapid heart rate, tremors, dizziness, and headaches. More severe cases can lead to chest pain, difficulty breathing, and even cardiac arrest. It is crucial to seek medical assistance promptly and provide healthcare professionals with details regarding the quantity consumed to ensure appropriate treatment and prevent potential complications.

In the case of a missed dose of Terbutaline Syrup/Suspension, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise adjusting the dosage or provide specific instructions to ensure the medication's effectiveness. It is crucial to follow the prescribed treatment plan for optimal results.

To use Terbutaline Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and take it orally as directed by your healthcare provider, typically two or three times a day, at evenly spaced intervals, to ensure effective bronchodilation and relief from respiratory symptoms.

Following are the conditions/situations when Terbutaline Syrup/Suspension should not be used:

• Must not be used in individuals with a known allergy to Terbutaline or related medications.
• Not suitable for people with certain heart conditions, such as tachycardia or recent heart attack.
• Contraindicated in patients with severe hypertension (high blood pressure).
• Should not be used in individuals with a history of seizures or epilepsy.
• Not recommended for those with diabetes, as it can interfere with blood sugar control.
• Must be avoided during breastfeeding, as it can pass into breast milk.
• Not suitable for individuals with narrow-angle glaucoma.
• Contraindicated in patients with pheochromocytoma.
• Should not be used in patients with severe kidney disease.
• Avoid use in individuals with a history of pulmonary edema.

The side effects of Terbutaline Syrup/Suspension may include:

• Increased heart rate (tachycardia)
• Nervousness or anxiety
• Dizziness or lightheadedness
• Tremors or shaking
• Headache
• Nausea or vomiting
• Fatigue or weakness
• Muscle cramps

Following are the precautions and warnings for Terbutaline Syrup/Suspension:

• Terbutaline should be used with caution in patients with heart problems, hypertension, or diabetes as it may worsen these conditions.
• It may cause hypokalemia (low potassium levels); regular monitoring of potassium levels is necessary during treatment.
• Not recommended for patients with a history of seizures, as it may lower the seizure threshold.
• Patients with thyroid disorders should be closely monitored as Terbutaline can affect thyroid function.
• Elderly patients may be more sensitive to the effects and should be monitored for adverse reactions.
• This medication may cause dizziness and blurred vision, so caution is advised when performing tasks that require alertness.
• Terbutaline should be discontinued if signs of paradoxical bronchospasm or allergic reactions occur.

Following are the drug interactions for Terbutaline Syrup/Suspension:

• Beta-blockers, such as propranolol, can counteract the effects of terbutaline, as they block beta-adrenergic receptors.
• Monoamine oxidase inhibitors (MAOIs) should be avoided, as terbutaline may interact with them, leading to increased cardiovascular side effects.
• Diuretics, especially potassium-depleting types, can cause hypokalemia, which may increase the risk of arrhythmias when used with terbutaline.
• Concomitant use with digoxin can increase the risk of cardiac arrhythmias due to potential electrolyte imbalances.
• Terbutaline may reduce the effectiveness of insulin and oral hypoglycemic drugs, requiring close monitoring of blood glucose levels.
• Theophylline levels may be increased when used with terbutaline, requiring dose adjustments to avoid toxicity.
• Antihypertensive medications may be less effective when combined with terbutaline due to its potential to increase blood pressure and heart rate.

Following are the food interactions for Terbutaline Syrup/Suspension:

• Avoid caffeine-containing products like coffee, tea, energy drinks, and certain soft drinks, as Terbutaline may increase the effects of caffeine, leading to potential issues like increased heart rate and blood pressure.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of Terbutaline, potentially leading to increased drug levels in the body and an elevated risk of side effects.
• Alcohol consumption should be limited as it may enhance the sedative effects of Terbutaline, causing excessive drowsiness and dizziness.
• Avoid high-fat meals as they may slow down the absorption of Terbutaline, affecting its rapid onset of action.
• Spicy foods and carbonated beverages may increase stomach acid production, which could potentially interfere with the effectiveness of Terbutaline, especially in individuals with gastrointestinal issues.
• Chocolate contains a compound called methylxanthine, which may interact with Terbutaline, potentially causing increased heart rate and blood pressure.
• Avoid herbal supplements like St. John's Wort, as it may alter Terbutaline's metabolism, affecting its efficacy and safety.
• Always consult a healthcare professional for personalized advice, especially if you have a specific diet or medical condition that may influence drug interactions.

Terbutaline Syrup/Suspension should be stored in a secure and controlled environment, preferably in a designated medicine cabinet or storage area. Keep it at room temperature, maintaining a consistent temperature between 68°F to 77°F (20°C to 25°C). Avoid exposing the medication to direct sunlight, heat, or moisture, as these can degrade its quality. Always keep the syrup in its original container, tightly sealed, to prevent contamination and ensure its integrity. When disposing of unused or expired Terbutaline Syrup/Suspension, do not pour it down the drain or flush it down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal, or consult a pharmacist for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental ingestion, as it is meant for prescribed use only.

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Following are the quick tips for Terbutaline Syrup/Suspension:

• Consult a doctor for prescription and dosage instructions tailored to your condition.
• Administer the correct dose using an accurate measuring device.
• Take the syrup as prescribed, typically three times a day, and follow the prescribed duration.
• Ensure you understand the prescribed dosage and clarify any doubts with your healthcare provider.
• Store the medication at room temperature, away from moisture and sunlight.
• Do not freeze the syrup.
• Keep a record of your medication usage and inform your doctor of any side effects.