Micropirin (75mg) 56 Tablets

Aspirin 75MG Tablet (acetylsalicylic acid) primarily exerts its therapeutic effects through its ability to irreversibly inhibit the enzyme cyclooxygenase (COX), which exists in two isoforms,COX-1 and COX-2. At this low dose (75mg), aspirin selectively inhibits COX-1, leading to reduced production of thromboxane A2, a potent stimulator of platelet aggregation and vasoconstiction. By inhibiting thromboxane A2 production, aspirin impairs the ability of platelets to aggregate and form clots, thereby exerting its anti-platelet and antithrombotic effects. This mechanism of action is crucial in the prevention of arterial thrombosis and is the basis for aspirin's use in reducing the risk of cardiovascular events such as heart attacks and strokes.

Aspirin 75MG

Antiplatelet/Non-steroidal anti-inflammatory drug (NSAID)

Tablet

The following are the uses of Aspirin 75MG Tablet:

• Used for preventing blood clots, reducing the risk of heart attack and stroke.
• Used to relieve mild to moderate pain, including headaches, toothaches, and muscle pain.
• Used for reducing inflammation and managing conditions like arthritis.
• Used as an anti-inflammatory for conditions such as rheumatoid arthritis and osteoarthritis.
• Used for lowering fever and reducing discomfort during illnesses like the flu or common cold.
• Used in the treatment of certain types of chest pain (angina) and circulation issues.
• Used for its antiplatelet effect, helping to prevent the formation of harmful blood clots.

In the case of an overdose of Aspirin 75MG tablets, several symptoms may occur, including ringing in the ears, nausea, vomiting, and abdominal pain. More severe cases can lead to rapid breathing, confusion, and even seizures. Immediate medical intervention is necessary, as prompt treatment can prevent serious complications. Treatment may involve stomach pumping or administering activated charcoal to prevent further absorption of the drug. It is crucial to seek medical help promptly to manage these symptoms effectively.

In the case of a missed dose of Aspirin 75MG Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your medication. It is important to maintain a consistent dosing schedule for the best therapeutic effect.

To take Aspirin 75MG Tablet, swallow the tablet whole with a full glass of water, preferably with or after food, following the dosage instructions provided by your healthcare professional, which may include a specific time interval between doses to ensure its effectiveness and minimize the risk of side effects.

Following are the conditions or circumstances when Aspirin 75MG Tablet should not be taken:

• Do not take Aspirin 75MG Tablet if you have a known allergy or hypersensitivity to aspirin, other salicylates, or non-steroidal anti-inflammatory drugs (NSAIDs).
• Avoid using this medication if you have a history of asthma attacks, hives, or other allergic reactions triggered by aspirin or similar medications.
• Not suitable for individuals with active stomach bleeding, ulcers, or bleeding disorders.
• Should not be used in patients with severe liver or kidney impairment.
• Contraindicated in individuals who have recently undergone heart surgery (e.g., coronary artery bypass graft surgery).
• Do not give this medication to children and teenagers with fever, especially if they have flu or chickenpox symptoms.
• Avoid using this medication if you are in the third trimester of pregnancy, as it may cause complications.

The side effects of Aspirin 75MG Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Heartburn or indigestion
• Easy bruising or bleeding (e.g., nosebleeds, bleeding gums)
• Ringing in the ears (tinnitus)
• Allergic reactions (such as rash, itching, swelling)
• Gastrointestinal bleeding
• In rare cases, liver or kidney problems

Here are the precautions and warnings for Aspirin 75MG Tablet:

• Aspirin should not be used in individuals with a known allergy to salicylates or other non-steroidal anti-inflammatory drugs (NSAIDs).
• It is crucial to avoid using Aspirin in patients with active peptic ulcers or a history of gastrointestinal bleeding, as it may increase the risk of bleeding.
• Caution is advised for patients with asthma, as Aspirin can trigger or worsen asthma symptoms.
• Aspirin may prolong bleeding time, so it should be used with caution in patients with bleeding disorders or those undergoing surgery.
• Kidney function should be monitored in long-term use, especially in patients with pre-existing kidney problems.
• Not recommended for children and adolescents under 16 years of age with a fever, as it may be associated with Reye's syndrome.
• Consult a healthcare professional before use during pregnancy and breastfeeding, as it may have potential risks for the fetus and infant.
• Always inform your doctor about other medications you are taking to avoid potential drug interactions.

Following are the drug interactions for Aspirin 75MG Tablet:

• May reduce the blood pressure-lowering effects of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and beta-blockers.
• Can increase the risk of bleeding when taken with anticoagulants like warfarin, heparin, or antiplatelet drugs (e.g., clopidogrel).
• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen may decrease the anti-inflammatory effects of aspirin and increase the risk of gastrointestinal bleeding.
• Aspirin can interact with diuretics, potentially reducing their diuretic and antihypertensive effects.
• May reduce the effectiveness of certain diabetes medications, including insulin and oral hypoglycemic agents.
• Could potentially decrease the excretion of methotrexate, leading to increased methotrexate levels and toxicity.
• Probenecid, used to treat gout, can reduce the elimination of aspirin, resulting in higher aspirin levels in the body.

Following are the food interactions for Aspirin 75MG Tablet:

• Avoid excessive alcohol consumption while taking Aspirin, as it can increase the risk of stomach bleeding and liver damage.
• Limit caffeine intake from coffee, tea, or energy drinks as it can enhance the effect of Aspirin on blood thinning.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with Aspirin's metabolism, potentially increasing its blood levels.
• High-salt foods should be minimized as Aspirin is often used to reduce salt and water retention, and a high-salt diet may counteract its therapeutic effects.
• Avoid fatty or greasy foods, as they can slow down the absorption of Aspirin, delaying its effect.
• Consuming a full glass of water with the tablet is recommended to aid in its dissolution and absorption.
• Dairy products like milk or cheese might decrease the absorption of Aspirin, so consider taking the tablet with water first before consuming dairy.
• Certain vegetables like broccoli, spinach, and kale, which are rich in vitamin K, might interact with Aspirin's blood-thinning effects, so maintaining a consistent diet is advisable.

Aspirin 75MG Tablets should be stored in a cool, dry area, away from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid placing the medication in the bathroom or near heat sources, as temperature fluctuations can impact its effectiveness. Always check the expiration date and never use the tablets beyond this date. Dispose of any unused or expired aspirin properly; do not flush or pour it down the drain. Consult your pharmacist for guidance on appropriate disposal methods. Ensure the tablets are kept out of children's reach to prevent accidental consumption.

Following are the quick tips for Aspirin 75MG Tablet:

• Consult your doctor before use, especially if you have a medical condition or are taking other medications.
• Take the tablet with a full glass of water to aid in swallowing and prevent stomach irritation.
• Avoid breaking or crushing the tablet; take it as a whole.
• Maintain a consistent dosing schedule for maximum effectiveness.
• Do not exceed the recommended dosage; it may increase the risk of side effects.
• Inform your doctor if you have a history of stomach ulcers or bleeding disorders.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Always read the patient information leaflet provided with the medication.