MIN D 50000 IU SACHETS (4S)

Cholecalciferol, also known as vitamin D3, has a primary mechanism of action centered on its role in calcium and phosphate homeostasis. When administered orally, cholecalciferol is absorbed in the small intestine and transported to the liver, where it undergoes hydroxylation to form 25-hydroxyvitamin D (calcidiol). This metabolite is further converted in the kidneys to its active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol acts as a hormone, binding to the vitamin D receptor (VDR) in various target cells, primarily in the intestines, bones, and kidneys. This binding activates the VDR, which then regulates gene expression, leading to increased intestinal absorption of calcium and phosphorus, promoting bone mineralization, and supporting overall bone health. Additionally, cholecalciferol influences immune function and cellular proliferation through its actions on the VDR.

Cholecalciferol 50,000iu

Vitamin D3 analog.

Sachet

The following are the uses of Cholecalciferol 50,000iu Sachet:

• Used for the treatment of Vitamin D deficiency
• Used to prevent and treat rickets and osteomalacia
• Used for maintaining healthy bones and teeth
• Used to support calcium absorption and bone density
• Used in cases of limited sun exposure or malabsorption issues
• Used to regulate the immune system and reduce inflammation
• Used to support muscle function and overall health
• Used as a supplement during pregnancy and breastfeeding to ensure adequate Vitamin D levels

In the case of an overdose of Cholecalciferol 50,000 IU sachets, individuals may experience symptoms such as nausea, vomiting, constipation, weakness, and confusion. Excessive intake can lead to hypercalcemia, characterized by elevated calcium levels in the blood. This condition may cause kidney damage, dehydration, and, in severe cases, cardiac arrhythmias. Prompt medical intervention is necessary to manage the symptoms and prevent potential complications associated with Cholecalciferol overdose.

In the case of a missed dose of Cholecalciferol 50,000 IU sachet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen. It's important to follow the prescribed dosage instructions to ensure the medication's effectiveness and to minimize any potential side effects.

To use Cholecalciferol 50,000iu Sachet, empty the contents of the sachet directly onto your tongue or mix it with a small amount of water or juice, and consume it once a week, preferably at the same time each week, as directed by your healthcare professional.

Following are the conditions or situations when Cholecalciferol 50,000 IU Sachet should not be taken:

• Avoid if you have a known allergy or hypersensitivity to Cholecalciferol or any of its ingredients.
• Do not take if you have elevated calcium levels in your blood (hypercalcemia) or conditions causing calcium excess.
• Contraindicated in individuals with kidney stones or a history of kidney disease.
• Should not be used in patients with uncontrolled hyperparathyroidism.
• Avoid if you have a condition called vitamin D toxicity or hypervitaminosis D.
• Not suitable for individuals with conditions causing high blood calcium levels, such as sarcoidosis or lymphoma.
• Do not take if you have a condition called hypercalciuria, which is high levels of calcium in the urine.

The side effects of Cholecalciferol 50,000 IU Sachet may include:

• Nausea and vomiting.
• Diarrhea or constipation.
• Loss of appetite.
• Fatigue and weakness.
• Dry mouth.
• Metallic taste in the mouth.
• Muscle or joint pain.
• Increased thirst and frequent urination.

Following are the precautions and warnings for Cholecalciferol 50,000 IU Sachet:

• Avoid taking high doses of vitamin D without medical supervision, as it may lead to vitamin D toxicity.
• Regular monitoring of calcium and vitamin D levels is necessary during long-term treatment.
• Patients with kidney disease, hyperparathyroidism, or conditions causing high blood calcium levels should use it with caution.
• Not recommended for individuals with hypercalciuria (high calcium in urine) or kidney stones.
• May cause an increase in calcium levels in patients with sarcoidosis, so regular monitoring is essential.
• Not suitable for individuals with a known allergy to Cholecalciferol or any of its excipients.
• Exercise caution when combining with other vitamin D supplements or calcium-rich medications to prevent excessive intake.

Following are the drug interactions for Cholecalciferol 50,000 IU Sachet:

• Thiazide diuretics can decrease the excretion of vitamin D, leading to potential hypercalcemia.
• Anticonvulsants like phenobarbital and phenytoin can decrease vitamin D levels, reducing its effectiveness.
• Orlistat and cholestyramine may decrease the absorption of vitamin D, requiring higher doses.
• Calcium supplements and antacids containing calcium may compete for absorption with vitamin D.
• Aluminum-containing antacids can decrease vitamin D absorption.
• Corticosteroids can increase vitamin D metabolism, potentially requiring higher doses.
• Vitamin D may increase the risk of hypercalcemia when used with calcium-containing drugs or digoxin.

Following are the food interactions for Cholecalciferol 50,000 IU Sachet:

• Consuming excessive amounts of vitamin D-rich foods like fatty fish (salmon, mackerel), egg yolks, and fortified dairy products alongside Cholecalciferol supplementation can lead to vitamin D toxicity, causing symptoms such as nausea, vomiting, and constipation.
• Vitamin D is a fat-soluble vitamin, so taking it with a small meal containing healthy fats can enhance its absorption. Consider pairing it with foods like avocado, nuts, or olive oil.
• Avoid excessive consumption of calcium-rich foods like dairy products, kale, and broccoli while on Cholecalciferol, as it can lead to elevated calcium levels in the blood.
• Grapefruit and grapefruit juice should be limited as they can interfere with vitamin D metabolism, potentially affecting its effectiveness.
• Alcohol may decrease the absorption of vitamin D, so it's advisable to limit alcohol consumption during the supplementation period.
• Avoid taking Cholecalciferol with high-fiber foods like whole grains, legumes, and certain vegetables as fiber can bind to the vitamin, reducing its absorption.
• Always take Cholecalciferol with a glass of water as directed by your healthcare provider to ensure proper dissolution and absorption.

Cholecalciferol 50,000iu Sachet should be stored in a cool and dry environment, preferably at room temperature, ensuring it is shielded from direct sunlight and moisture. It is crucial to maintain the medication in its original packaging, securely sealed, to prevent contamination. Avoid storage in humid areas like bathrooms or near heat-emitting appliances, as temperature fluctuations can compromise the medication's integrity. Prior to usage, always verify the expiration date, and for the safe disposal of any unused or expired sachets, refrain from flushing or pouring them into drainage systems. Instead, seek guidance from a pharmacist or healthcare professional for appropriate disposal practices. Additionally, keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 50,000iu Sachet:

• Consult your doctor before use, especially if you have kidney or liver disease.
• Take the sachet as directed by your healthcare provider, usually once a week or as prescribed.
• Consume the entire contents of the sachet in one go, do not save for later use.
• Open the sachet carefully and pour the powder directly into your mouth or mix with water/juice.
• Ensure you take the sachet on the same day each week to maintain consistency.
• Store the sachets in a cool, dry place, away from direct sunlight and moisture.
• Do not use if the sachet is torn or shows signs of tampering.