Mobikare SR (100mg) 20 Capsules

Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID), exerts its mechanism of action primarily by inhibiting the production of prostaglandins, which are key mediators of inflammation and pain. It achieves this effect by blocking cyclooxygenase (COX) enzymes, particularly COX-2, which is responsible for the conversion of arachidonic acid into prostaglandin H2, a precursor to various prostaglandins. By suppressing COX-2 activity, diclofenac sodium reduces the synthesis of prostaglandins at the site of inflammation, thereby alleviating pain, reducing inflammation, and decreasing fever. This selective inhibition of COX-2 also contributes to its therapeutic effects in conditions like arthritis, where inflammation and pain are prevalent.

Diclofenac Sodium 100mg

Non-steroidal anti-inflammatory drug (NSAID)

Capsule

The following are the uses of Diclofenac Sodium 100mg Capsule:

• Used for relieving acute pain, such as post-surgical pain, dental pain, or pain from injuries.
• Used for reducing inflammation and managing pain in conditions like arthritis, ankylosing spondylitis, and gout.
• Used for treating menstrual cramps and pain associated with primary dysmenorrhea.
• Used for providing relief from migraine headaches and other types of headaches.
• Used for managing pain and inflammation in soft tissue injuries and sprains.
• Used for reducing fever and providing comfort in cases of flu or other viral infections.
• Used for alleviating pain and swelling after minor surgical procedures.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For pain relief from moderate to severe osteoarthritis of the knee- 100 mg to 150 mg, taken as a single dose or divided into 2 doses (1 tablet of 100 mg 3 times per day).
• For pain relief from rheumatoid arthritis- 100 mg to 150 mg taken once a day or divided into 2 doses (1 tablet of 100 mg 3 times per day).
• For analgesia after dental surgery- 1.8 mg/kg (maximum 150 mg) taken once either before or after surgery.
• For analgesia after general surgery- 2 mg/kg (maximum 200 mg) taken once either before or after surgery.
• For non-specific muscle pain and spasms- 50 mg to 100 mg taken once or twice a day.
• For migraine pain- Initially, 50 mg to 100 mg taken once, and then 25 mg to 50 mg every four hours as needed.
• Maximum dose in a day for oral formulations should not exceed 200 mg

In the case of an overdose of Diclofenac Sodium 100mg Capsules, individuals may experience symptoms such as nausea, vomiting, stomach pain, and gastrointestinal bleeding. The severity of the effects can vary depending on the amount ingested. It is crucial to seek medical assistance promptly if an overdose is suspected. Medical professionals will provide appropriate treatment, which may include inducing vomiting, administering activated charcoal, and monitoring vital signs to ensure the patient's safety and well-being.

In the case of a missed dose of Diclofenac Sodium 100mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss several doses, contact your healthcare provider for advice, as they may recommend adjusting your dosing schedule or provide guidance on how to proceed safely. It is best to set reminders or keep the medication in a visible place to help you remember to take it as prescribed.

To take Diclofenac Sodium 100mg Capsule, swallow the capsule whole with a full glass of water, preferably with or after a meal, once or twice a day as directed by your doctor or pharmacist, ensuring you follow the prescribed dosage and duration for your specific condition.

Following are the conditions or circumstances when Diclofenac Sodium 100mg Capsule should not be taken:

• Do not take if you have a known allergy or hypersensitivity to Diclofenac or other related non-steroidal anti-inflammatory drugs (NSAIDs).
• Avoid using if you have a history of asthma attacks or severe allergic reactions triggered by aspirin or other NSAIDs.
• Not suitable for individuals with active or recent gastrointestinal bleeding.
• Contraindicated in patients with severe heart failure or heart disease.
• Do not use if you have a history of stomach or intestinal ulcers or bleeding.
• Should not be taken during the last trimester of pregnancy.
• Avoid using if you have severe kidney or liver impairment.
• Not recommended for individuals with bleeding disorders or those taking blood-thinning medications.
• Do not administer to children under 18 years of age without medical advice.
• Contraindicated in patients with certain blood vessel diseases, such as peripheral arterial disease.

The side effects of Diclofenac Sodium 100mg Capsule may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea or constipation
• Dizziness or vertigo
• Headache
• Skin rashes or itching
• Increased blood pressure
• Fatigue or drowsiness

Following are the precautions and warnings for Diclofenac Sodium 100mg Capsule:

• This medication should not be used in individuals with a known allergy to diclofenac or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Diclofenac may increase the risk of serious cardiovascular events, including heart attack and stroke, especially with long-term use. Patients with cardiovascular disease or risk factors should be closely monitored.
• Gastrointestinal bleeding and perforation are possible risks. Patients with a history of gastrointestinal issues like ulcers or bleeding should exercise caution and inform their doctor.
• The use of Diclofenac may lead to liver dysfunction. Regular monitoring of liver function is recommended, especially during long-term treatment.
• Kidney function should be monitored as diclofenac can cause renal impairment, particularly in patients with pre-existing kidney issues or those taking diuretics.
• Elderly patients may be more susceptible to side effects; therefore, lower doses should be considered initially.
• It is important to avoid using this medication during pregnancy, especially in the third trimester, as it may cause adverse effects on the fetal cardiovascular system.
• Consult a healthcare professional before taking Diclofenac if you have a history of any cardiovascular, gastrointestinal, or liver-related disorders.

Following are the drug interactions for Diclofenac Sodium 100mg Capsule:

• May increase risk of bleeding when taken with anticoagulants like warfarin, clopidogrel, or heparin.
• Can reduce the effectiveness of antihypertensive medications such as beta-blockers, ACE inhibitors, and diuretics.
• Concomitant use with other non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding and kidney damage.
• Diclofenac may interact with lithium, potentially increasing lithium levels in the body, which can be harmful.
• Using Diclofenac with diuretics like furosemide may decrease its diuretic effect and increase the risk of kidney toxicity.
• Taking corticosteroids with Diclofenac may increase the risk of gastrointestinal bleeding and delay wound healing.
• May reduce the effectiveness of anti-diabetic medications, potentially requiring adjustments in insulin or oral hypoglycemic doses.

Following are the food interactions for Diclofenac Sodium 100mg Capsule:

• Alcohol consumption should be avoided as it can increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Diclofenac, leading to increased drug levels in the body.
• Limit the intake of foods rich in vitamin K (like spinach, kale, and broccoli) as Diclofenac can interfere with blood clotting, and vitamin K plays a role in this process.
• Avoid excessive caffeine intake as it may increase the risk of stomach irritation and interfere with the absorption of Diclofenac.
• Dairy products like milk and cheese might reduce the absorption of Diclofenac, so consider taking the medication with water instead.
• Avoid high-sodium foods, as Diclofenac can cause sodium retention, leading to fluid retention and increased blood pressure.
• Consuming fatty or greasy foods might delay the absorption of Diclofenac, so it is best to take the medication on an empty stomach.
• There is no known interaction with garlic, but it may potentially increase the risk of bleeding when taken with Diclofenac.

Diclofenac Sodium 100mg Capsules should be stored in a secure and dry location, away from direct sunlight and moisture. Maintain the capsules in their original packaging, ensuring the container is tightly sealed to prevent exposure to air and potential contamination. It is crucial to avoid storing them in bathrooms or near heat sources like ovens or radiators, as temperature fluctuations can impact the medication's effectiveness. Regularly check the expiration date, and if the capsules are no longer needed or have expired, proper disposal is essential. Do not flush them or pour them down the drain; instead, consult a pharmacist or healthcare professional for safe disposal guidelines. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Diclofenac Sodium 100mg Capsule:

• Take the capsule with a full glass of water, preferably with food or after meals.
• Swallow the capsule whole, do not crush or chew it.
• Maintain a consistent dosing schedule, ideally at the same time each day.
• Avoid taking antacids within 2 hours of this medicine.
• Inform your doctor if you have a history of stomach problems or cardiovascular issues.
• Do not lie down immediately after taking the capsule, stay upright to prevent irritation.
• If you experience dizziness, avoid driving or operating heavy machinery.

Diclofenac sodium is a standout pain-relieving medication and reducer of inflammation and fever, frequently used to treat rheumatoid arthritis, osteoarthritis, and other joint pain. This medication should be used with caution and under a doctor's supervision, although it is not a prescription drug. Depending on the individual's needs, various lab tests may be required, particularly if they have underlying medical conditions that require close monitoring. Discussing other necessary lab tests with your doctor is recommended if you have specific medical conditions or are taking other medications. Your doctor may recommend regular blood tests to monitor your blood cells, liver and kidney function, and other essential markers. This is done to identify any signs of anemia or thrombocytopenia resulting from long-term use. Regular liver and kidney function tests are necessary to ensure the medication is not causing any undue stress on these organs. Periodic blood pressure checks with your doctor may also be recommended, given diclofenac sodium's effect on blood pressure and the potential for issues with kidney function. Additionally, electrolyte panels may be monitored to ensure potassium levels are within the normal range, helping identify any issues with kidney function and assisting in managing the side effects of the medication. Conducting these lab tests periodically or as needed, under the guidance of your healthcare provider, is essential to ensure diclofenac sodium's safety and efficacy, considering your individual circumstances.