Modton (25mg) 10 Tablets

Melatonin receptors MT1 and MT2 play a significant role in regulating our body's circadian rhythm, a natural, internal process that involves the regulation of sleep and wakefulness. Agomelatine is a novel antidepressant with a unique mechanism of action. It acts as a selective agonist for these receptors, meaning that it stimulates these receptors to counteract the effects of depression and insomnia. Agomelatine is the first drug to behave in this way, making it a valuable tool in the treatment of depression. Depressive symptoms and insomnia are commonly experienced together, and agomelatine's ability to regulate patients' sleep cycles can help alleviate both. Its action on melatonin receptors is thought to affect the circadian rhythm, contributing to its antidepressant properties. Additionally, agomelatine has an affinity for the 5-HT2C receptor, which has been observed to play a role in the regulation of the serotonin hormone, which is closely linked to mood.

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Selective Serotonin Receptor 2C (5-Ht2C) Antagonist And Melatonin Receptor Mt1 And Mt2 Agonist

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Tablet

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Unveiling its multifaceted uses and transformative applications as follows:

• Agomelatine is used to treat Major Depressive Disorder (MDD).
• Agomelatine is used to treat Dysomnia (primarily sleep maintenance disorder).
• Agomelatine is sometimes used in combination with antidepressants to treat insomnia.
• It is used off-label for ADHD, bipolar disorder, and anxiety.

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Starting dose for Major Depressive Disorder is 25mg once daily at bedtime, with a maximum of 100mg per day.
• For GAD, the recommended starting dose is 25 mg once daily, with a maximum of 50mg per day.
• The dose for other psychiatric disorders is adjusted based on the specific condition, severity, and patient response.

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Agomelatine overdose is a medical emergency and should be treated as such. If you suspect someone has overdosed, seek medical attention right away or contact your local emergency hotline. The specific treatment may include gastrointestinal decontamination, activated charcoal, flumazenil, or dialysis. In consultation with a medical professional, the treatment will be tailored to the patient's history, the amount, and time since the overdose. They may also prescribe further treatments and advise on follow-up care. It is essential to note that aggressive monitoring and treatment are required, as well as emotional and psychological support for the patient, due to the potential severity of symptoms and complications.

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Maintaining a regular agomelatine dosage schedule is important because it helps to keep the level of medicine in your blood steady. This means you get the most benefit from the treatment. If you forget to take a dose, then take it as soon as possible, unless it is almost time for your next dose. If this is the case, it is best to skip the missed dose and stay on your regular regimen. Because agomelatine can make you tired, drowsy, or blur your vision, it is important to be careful when driving or operating machinery. It is advisable to contact your healthcare provider if you have any questions or concerns about your treatment plan.

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Before starting to take Agomelatine, it is crucial to read the patient information leaflet supplied by the manufacturer. This leaflet will contain detailed information on the medication's dosage, safety, and side effects, specific to the product supplied. Here is a general guide to help you understand how to take Agomelatine 25mg tablets:

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Discerning instances where this medication may not be appropriate:

• You are allergic to Agomelatine or any of the other ingredients in this medication.
• You are taking linezolid, a medication used to treat certain types of bacterial infections.
• In these situations, it is best to consult a medical professional before taking Agomelatine 25mg.

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Unraveling the side effects lurking behind this medications are as follows:

• Sleepiness & Weakness
• Dry Mouth
• Upset stomach
• Constipation
• Diarrhea
• Headaches
• Persistent thirst
• Muscle pain
• Backaches
• Joint pain

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The warnings and precautions associated with Agomelatine are:

• Patient with bipolar disorder, mania, hypomania.
• Diabetes mellitus, non-alcoholic fatty liver disease.
• Pre-treatment elevated transaminases.
• History of suicide-related events or those who exhibit significant degree of suicidal ideation.
• Obese and alcoholic patients, smokers.
• Moderate to severe renal impairment.

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The drug interactions with agomelatine include:

• CYP1A2 Inhibitors – Can increase agomelatine levels.
• CYP2C9 Inhibitors – May alter agomelatine levels.

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For Agomelatine, food interactions that should be considered are:

• Avoid consuming alcohol as it may increase the risk of side effects.

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Store this medication in a cool, dry place, away from direct sunlight and moisture, at room temperature (15-25°C). Keep it in its original container and out of reach of children and pets. Avoid storing it in bathrooms or areas prone to humidity. Properly dispose of any unused or expired medication according to local regulations or through a pharmacy take-back program to ensure safe disposal. Avoid flushing it down the toilet or pouring it into drains unless instructed to do so.

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