MONT FEX 4/30MG SYP 60ML

Montelukast sodium and Fexofenadine work synergistically in this combination medication to alleviate allergy symptoms. Montelukast, a leukotriene receptor antagonist, blocks the action of leukotrienes, which are inflammatory mediators responsible for airway constriction and increased mucus production. By inhibiting the action of leukotriene receptors, it reduces inflammation in the airways. Fexofenadine, a second-generation antihistamine, competitively binds to peripheral histamine H1 receptors, preventing the release of histamine and subsequent allergic reactions. This dual action effectively reduces symptoms such as sneezing, itching, and nasal congestion associated with allergic conditions.

Leukotriene receptor antagonist + Histamine antagonist.

Suspension

The following are the uses of Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension:

• Used for relieving symptoms of seasonal allergies, such as runny nose, sneezing, and itchy, watery eyes.
• Used for managing chronic allergic rhinitis, providing long-term relief from persistent allergy symptoms.
• Used to prevent and treat asthma symptoms, particularly in patients with allergic asthma.
• Effective in reducing inflammation and narrowing of airways triggered by allergens.
• Used to alleviate skin itching and hives caused by allergic reactions, offering quick relief.
• Helps manage chronic urticaria, a condition of recurrent hives, by controlling immune responses.
• Provides relief from respiratory symptoms associated with allergic reactions to substances like pollen, dust mites, and pet dander.
• Used as a preventive measure for individuals prone to severe allergic reactions, ensuring their well-being.

In the case of an overdose of Montelukast sodium 4mg and Fexofenadine 30mg Syrup/Suspension, it is important to recognize the potential symptoms, which may include severe drowsiness, confusion, and gastrointestinal issues. Promptly seek medical assistance and provide healthcare professionals with the medication details. They will likely manage the overdose by providing supportive care and treating specific symptoms to ensure the patient's well-being.

In the case of a missed dose of Montelukast sodium 4mg, administer the medication as soon as you remember, but skip the dose if it's almost time for the next one. Do not double the dose to make up for the missed one. For Fexofenadine 30mg syrup/suspension, if a dose is missed, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Avoid taking extra medication to compensate for the missed dose.

To administer Montelukast sodium 4mg and Fexofenadine 30mg syrup/suspension, shake the bottle well, measure the prescribed dose with a syringe or dosing cup, and give it to your child once daily as directed by your healthcare provider, regardless of mealtimes.

Following are the conditions/situations when Montelukast sodium 4mg and Fexofenadine 30mg Syrup/Suspension should not be used:

• Avoid in individuals with a known allergy to Montelukast sodium, Fexofenadine, or any other ingredients in the medication.
• Not suitable for patients with severe liver or kidney disease.
• Should not be given to infants under 6 months old.
• Contraindicated in patients with a history of serious allergic reactions or anaphylaxis.
• Not recommended for individuals with a history of seizures or epilepsy.
• Avoid using this medication if you have an active infection or a weakened immune system.
• Do not use if you have a rare hereditary problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension may include:

• Diarrhea
• Stomach pain
• Nausea or vomiting
• Dizziness
• Fatigue or drowsiness
• Dry mouth
• Skin rash or itching
• Behavioral changes, such as agitation or irritability

Following are the precautions and warnings for Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension:

• This medication should not be used if you are allergic to any of its ingredients, including Montelukast or Fexofenadine.
• Patients with liver or kidney disease should use this medication with caution and under medical supervision as it may require dosage adjustments.
• Avoid driving or operating heavy machinery if you experience dizziness or sleepiness after taking this syrup.
• Do not consume alcohol while taking this medication as it may increase the risk of side effects.
• If you have phenylketonuria (PKU), be aware that some formulations may contain aspartame, which can be harmful to you.
• Children under 6 months of age should not be given this medication unless prescribed by a doctor.
• Pregnant and breastfeeding women should consult their healthcare provider before using this medication, as it may affect fetal development and pass into breast milk.
• Store the medication at room temperature, away from moisture and heat, and keep it out of the reach of children.

Following are the drug interactions for Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension:

• Erythromycin, a macrolide antibiotic, can increase the exposure of Montelukast, potentially requiring dose adjustments.
• Co-administration with Phenobarbital, a barbiturate, may reduce the effectiveness of Montelukast due to increased metabolism.
• Montelukast may increase the concentration of warfarin, an anticoagulant, requiring close monitoring of prothrombin time.
• Fexofenadine levels can be increased when taken with ketoconazole, an antifungal medication, leading to potential side effects.
• Theophylline, a bronchodilator, may interact with Fexofenadine, causing increased theophylline levels and potential toxicity.
• Grapefruit juice should be avoided as it can affect the metabolism of Fexofenadine, leading to higher drug concentrations.
• Caution is advised with CYP3A4 inhibitors like clarithromycin, as they may increase Fexofenadine levels and Montelukast exposure.

Following are the food interactions for Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of the medication, potentially leading to increased drug levels in the body.
• Alcohol consumption is generally not recommended with this medication as it may increase the risk of drowsiness and dizziness.
• Avoid consuming high-fat meals as they can potentially decrease the absorption of Fexofenadine, reducing its effectiveness.
• Caffeine-containing beverages should be limited as they may enhance the side effects of Montelukast, including restlessness and insomnia.
• Avoid eating large quantities of Seville oranges (often used in marmalades) as they contain compounds that can interact with the medication.
• Apple juice may decrease the effectiveness of Fexofenadine; consider taking the medication with water instead.
• Do not consume herbal teas or supplements without medical advice as some herbs may interact with the medication.
• Consult your healthcare provider for specific dietary recommendations as individual responses to medications can vary.

Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension should be stored in a controlled environment, preferably at room temperature (68°F to 77°F or 20°C to 25°C), in its original container with the cap tightly secured. Protect it from light, moisture, and excessive heat. Do not freeze the suspension. Always check the expiration date before use and dispose of any unused or expired medication properly. Avoid flushing or pouring it down the drain; instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for guidance on safe disposal practices. Keep this medication out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Montelukast sodium 4mg, Fexofenadine 30mg Syrup/Suspension:

• Always follow the dosage prescribed by your doctor; do not adjust the dose without medical advice.
• Shake the suspension well before each use to ensure proper medication distribution.
• Administer the syrup with a measuring cup or oral syringe for accurate dosing.
• Consume the syrup with a full glass of water for better absorption.
• Avoid consuming it with fruit juices, especially grapefruit juice, as it may affect drug absorption.
• Store the medication at room temperature, away from moisture and direct sunlight.
• Do not use the syrup if it has changed color or developed an unusual odor.