Moveryl (100mg) 20 Capsules

Celecoxib, a selective COX-2 inhibitor, exerts its mechanism of action by specifically targeting the cyclooxygenase-2 (COX-2) enzyme while having minimal effect on COX-1. By inhibiting COX-2, celecoxib blocks the conversion of arachidonic acid to prostaglandin H2, a key step in the synthesis of prostaglandins and thromboxanes. This selective inhibition reduces inflammation and pain without affecting the COX-1-mediated production of protective prostaglandins in the stomach, thus providing anti-inflammatory and analgesic effects with potentially reduced gastrointestinal side effects compared to non-selective NSAIDs.

Celecoxib 100mg

Non-steroidal anti-inflammatory drug (NSAID)

Capsule

The following are the uses of Celecoxib 100mg Capsule:

• Celecoxib 100mg capsules are used to relieve pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• It is effective in managing acute pain, such as pain following surgery or injury.
• Celecoxib is used for the treatment of menstrual cramps (dysmenorrhea) in women.
• It is prescribed for patients with juvenile rheumatoid arthritis to reduce joint pain and swelling.
• This medication is a nonsteroidal anti-inflammatory drug (NSAID) that specifically targets and inhibits the COX-2 enzyme, reducing pain and inflammation.
• Celecoxib can also be used to manage pain and inflammation in patients with gout or other musculoskeletal disorders.
• It may be prescribed as a part of the treatment plan for certain chronic pain conditions to improve mobility and quality of life.
• Celecoxib is taken orally and typically provides long-lasting pain relief, allowing patients to carry out daily activities with less discomfort.

To be used as per doctor's prescription

In the case of an overdose of Celecoxib 100mg Capsules, it is important to recognize the potential risks. Symptoms may include severe stomach pain, nausea, vomiting, and gastrointestinal bleeding. Immediate medical attention is necessary, and healthcare professionals should be contacted right away. Treatment may involve gastric lavage, supportive care, and monitoring for potential complications. Prompt action can help mitigate the adverse effects and ensure the best possible outcome.

In the case of a missed dose of Celecoxib 100mg Capsule, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is generally advised not to double the dose to make up for a missed one. If you have missed multiple doses, consult your healthcare professional for guidance on how to get back on track with your medication regimen safely.

To take Celecoxib 100mg Capsule, swallow the capsule whole with a full glass of water, preferably with food, once or twice a day as directed by your doctor, ensuring you follow the prescribed dosage and duration for optimal effectiveness and safety.

Here are the conditions and situations when Celecoxib 100mg Capsule should not be taken:

• Do not take if you have a known allergy to Celecoxib or any other sulfonamide-derived drugs.
• Contraindicated in individuals with severe kidney problems.
• Should not be used in patients with severe liver impairment.
• Not recommended for patients with high blood pressure that is not controlled.
• Avoid if you have a history of heart attack, stroke, or blood clots.
• Do not take if you are pregnant, especially during the last 3 months of pregnancy.
• Contraindicated for individuals with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• Should not be used in children under 2 years of age.

The side effects of Celecoxib 100mg Capsule may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Constipation
• Dizziness or lightheadedness
• Skin rash or itching
• Swelling of the legs and ankles (peripheral edema)
• Increased blood pressure

Following are the precautions and warnings for Celecoxib 100mg Capsule:

• Not recommended for individuals with known hypersensitivity or severe allergic reactions to Celecoxib or other NSAIDs.
• Patients with a history of cardiovascular events, hypertension, or congestive heart failure should use with caution and under medical supervision.
• Renal-impaired patients may require dosage adjustments and should be monitored closely.
• Not recommended for use during pregnancy, especially in the third trimester, due to potential harm to the fetus.
• Breastfeeding women should consult a healthcare professional before taking this medication as it may pass into breast milk.
• Elderly patients may be more susceptible to adverse effects; regular monitoring is advised.
• Avoid alcohol consumption while taking Celecoxib as it may increase the risk of gastrointestinal bleeding.
• Patients with a history of gastrointestinal issues like ulcers or bleeding should use with caution and report any abdominal pain or signs of bleeding.

Following are the drug interactions for Celecoxib 100mg Capsule:

• Aspirin or other NSAIDs can increase the risk of stomach bleeding or kidney problems when taken with Celecoxib.
• May reduce the blood pressure-lowering effect of ACE inhibitors like lisinopril or beta-blockers like metoprolol.
• The anticoagulant effect of warfarin may be enhanced, increasing the risk of bleeding.
• Lithium levels may be increased, potentially leading to lithium toxicity.
• Diuretics like furosemide may decrease kidney function when used with Celecoxib.
• Methotrexate levels can be elevated, increasing the risk of methotrexate toxicity.
• Corticosteroids and Celecoxib together may increase the risk of gastrointestinal issues.

Following are the food interactions for Celecoxib 100mg Capsule:

• Grapefruit and grapefruit juice should be consumed cautiously as they can inhibit CYP2C9, an enzyme involved in the metabolism of Celecoxib, potentially increasing its blood levels and risk of side effects.
• Alcohol intake is generally not recommended with Celecoxib as it can increase the risk of gastrointestinal bleeding and liver toxicity.
• Avoid excessive caffeine intake as it can increase the risk of heartburn and may interact with Celecoxib's ability to manage pain and inflammation.
• Foods rich in vitamin K, like leafy greens, should be consumed consistently as Celecoxib may slightly alter blood clotting.
• Maintain a balanced diet, as Celecoxib can sometimes cause fluid retention and edema.
• Avoid high-sodium foods, especially if you have high blood pressure, as Celecoxib may exacerbate sodium retention.
• Consult your healthcare provider for dietary recommendations, especially if you have pre-existing conditions like diabetes or heart disease.

Celecoxib 100mg Capsules should be stored in a secure and dry location, away from direct sunlight and moisture, ideally in a cool and dry place at room temperature. Ensure the medication bottle is tightly sealed to maintain its integrity and prevent contamination. Avoid storing it in areas prone to temperature fluctuations, such as bathrooms, kitchens, or near heat sources, as this can impact the drug's effectiveness. Always check the expiration date, and for proper disposal, consult your pharmacist or healthcare provider. It is crucial to keep the medication out of children's reach to prevent accidental consumption. Dispose of any unused or expired capsules according to local regulations, avoiding flushing or pouring them into drainage systems.

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Here are the quick tips for Celecoxib 100mg Capsule:

• Swallow the capsule whole with a full glass of water, preferably with food.
• Take the capsule as directed by your doctor, usually once or twice daily.
• Avoid crushing, chewing, or breaking the capsule as it may be harmful.
• Do not take more than the prescribed dose, and inform your doctor if your condition worsens.
• If you have a history of heart disease, high blood pressure, or stomach problems, inform your doctor before taking this medication.
• Store the capsules at room temperature, away from moisture and light.
• Regularly monitor your health and report any unusual symptoms to your healthcare provider.