Mydocalm (150mg) 30 Tablets

Tolperisone 150mg Tablet's primary mechanism of action is attributed to its ability to act as a muscle relaxant. It exerts its effects by targeting voltage-dependent sodium channels in the central and peripheral nervous system. Tolperisone blocks these sodium channels, leading to a reduction in the release of excitatory neurotransmitters, particularly glutamate. This inhibition decreases the excitability of motor neurons, resulting in muscle relaxation. Additionally, it may modulate calcium channels, further contributing to its muscle-relaxing properties. By selectively targeting these ion channels, Tolperisone helps alleviate muscle spasms and stiffness without significantly impacting muscle strength, making it useful in managing various conditions characterized by increased muscle tone.

Muscle relaxant

Tablet

The following are the uses of Tolperisone 150mg Tablet:

• Used for treating muscle spasms and associated pain, providing muscle relaxation.
• Used to alleviate discomfort and stiffness in conditions like back pain, neck pain, and muscle injuries.
• Used for managing muscle-related symptoms in neurological disorders, improving mobility and reducing spasticity.
• Used to ease muscle tension headaches and related neck stiffness, offering relief from pain and discomfort.
• Used for post-operative care to reduce muscle stiffness and aid in the recovery process.
• Used in the management of fibromyalgia, helping to reduce muscle pain and tenderness.
• Used to enhance physical rehabilitation and therapy outcomes by relaxing muscles and improving flexibility.

In the case of an overdose of Tolperisone 150mg tablets, individuals may experience symptoms such as drowsiness, dizziness, and muscle weakness. Nausea, vomiting, and in severe cases, respiratory depression and hypotension can occur. Prompt medical intervention is necessary, and emergency services should be contacted immediately. Treatment for overdose may include supportive measures like monitoring vital signs, gastric lavage, and administering activated charcoal to prevent further absorption of the medication.

In the case of a missed dose of Tolperisone 150mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you frequently forget doses, consider setting an alarm or asking a family member to remind you to take your medication as prescribed. It is important to maintain a consistent dosing schedule for optimal effectiveness.

To take Tolperisone 150mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, as directed by your healthcare professional, typically two to three times a day or as prescribed.

Here are the conditions or situations when Tolperisone 150mg Tablet should not be used:

• Should not be taken by individuals with a known allergy or hypersensitivity to Tolperisone or any of its excipients.
• Contraindicated in patients with myasthenia gravis (a neuromuscular disorder).
• Not recommended for individuals with severe liver or kidney impairment.
• Avoid using in patients with prolonged QT syndrome or a history of significant cardiac arrhythmias.
• Should not be administered to patients with a history of porphyria (a metabolic disorder).
• Contraindicated during pregnancy, especially in the first trimester.
• Not suitable for breastfeeding mothers.
• Do not use in children below 12 years of age due to insufficient data on safety and efficacy.
• Avoid in patients with known or suspected esophageal or gastrointestinal obstruction.
• Should not be used in patients with a history of severe adverse reactions to muscle relaxants.
• Not recommended for individuals with respiratory disorders that impair breathing.

The side effects of Tolperisone 150mg Tablet may include:

• Dry mouth
• Dizziness or drowsiness
• Fatigue
• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Skin rash or itching
• Allergic reactions (rare)

Following are the precautions and warnings for Tolperisone 150mg Tablet:

• Not recommended for individuals with known allergies to Tolperisone or any other muscle relaxant medications.
• Patients with a history of liver or kidney disease should exercise caution and consult a doctor, as dosage adjustments might be necessary.
• Elderly patients may be more sensitive to the side effects, hence, medical supervision is advised.
• This medication may cause dizziness or sleepiness; avoid driving or operating heavy machinery until you feel alert.
• Avoid consuming alcohol while taking this medication as it may intensify the drowsiness.
• Inform your doctor if you have any muscle or nerve-related disorders before starting this medication.
• Tolperisone may interact with other medications; disclose all medications you are currently taking to your healthcare provider.

Following are the drug interactions for Tolperisone 150mg Tablet:

• Alcohol may enhance the sedative effects of Tolperisone, leading to increased drowsiness and impaired motor skills.
• Antidepressants like SSRIs (Selective Serotonin Reuptake Inhibitors) can interact, potentially increasing the risk of serotonin syndrome.
• Tolperisone may intensify the effects of other muscle relaxants, leading to excessive muscle weakness and sedation.
• Drugs metabolized by CYP2D6 enzyme may have altered metabolism when taken with Tolperisone, affecting their effectiveness.
• The effectiveness of antihypertensive medications might be reduced by Tolperisone, requiring close monitoring of blood pressure.
• Opioid pain medications can have additive effects with Tolperisone, increasing the risk of respiratory depression.
• Anticonvulsant drugs may have their levels affected by Tolperisone, requiring monitoring and dose adjustments.

Following are the food interactions to be aware of when taking Tolperisone 150mg Tablet:

• Consuming grapefruit or grapefruit juice is not recommended as it may influence the metabolism of Tolperisone, potentially altering its effectiveness.
• Alcohol should be avoided as it can enhance the sedative effects of Tolperisone, increasing the risk of dizziness and drowsiness.
• Caffeine intake should be monitored as it may counteract the muscle-relaxant effect of Tolperisone, reducing its therapeutic benefit.
• High-fat meals can slow down the absorption of Tolperisone, possibly affecting its onset of action.
• Dairy products may interfere with the absorption of Tolperisone, so it's best to avoid consuming them simultaneously.
• Spicy foods may increase the metabolism of Tolperisone, potentially reducing its effectiveness.
• Avoid herbal teas containing St. John's Wort as it may interact with Tolperisone's metabolism.
• Always consult your healthcare provider for personalized advice regarding dietary considerations while taking this medication.

Tolperisone 150mg Tablets should be stored in a secure and dry location, preferably at room temperature, ensuring it remains out of direct sunlight and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or areas exposed to heat, as temperature fluctuations can impact their effectiveness. Regularly check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of it in sinks or toilets; instead, seek guidance from a pharmacist or healthcare professional for safe disposal practices. Lastly, always keep medications, including Tolperisone tablets, out of children's reach to prevent accidental consumption.

Following are the quick tips for Tolperisone 150mg Tablet:

• Take the tablet as directed by your doctor, typically 1-3 times a day.
• Swallow the tablet whole with a full glass of water, preferably with or after meals.
• Maintain a consistent schedule for taking the medication for best results.
• Do not crush, chew, or break the tablet, as it may affect its effectiveness.
• Inform your doctor if you have liver or kidney problems before taking this medication.
• Be cautious if you are elderly, as side effects may be more pronounced.
• Store the medication at room temperature, away from moisture and light.