Mydocalm (50mg) 30 Tablets

Tolperisone 50mg Tablet primarily exerts its muscle relaxant effects through central and peripheral mechanisms. Centrally, it acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, reducing excitatory neurotransmission and decreasing muscle spasticity. Peripherally, tolperisone inhibits voltage-gated sodium and calcium channels, leading to the relaxation of skeletal muscles by reducing neuronal excitability and blocking the release of excitatory neurotransmitters. This dual mechanism of action contributes to its effectiveness in alleviating muscle spasms and associated symptoms without causing significant sedation or cognitive impairment.

Muscle relaxant.

Tablet

The following are the uses of tolperisone 50mg Tablet:

• Used for treating muscle stiffness and spasms, providing relief from pain and discomfort.
• Used to relax muscles and improve mobility, especially in conditions like back pain, neck pain, and muscle injuries.
• Used for managing symptoms of spasticity related to neurological disorders, aiding in muscle control and reducing excessive tension.
• Used to alleviate muscle tightness and cramps, enhancing flexibility and range of motion.
• Used in post-operative care to aid in muscle recovery and reduce stiffness, promoting a faster return to normal function.
• Used for managing muscle-related headaches and tension, providing relaxation and reducing pain.
• Used to improve overall muscle health and function, aiding in daily activities and exercise performance.
• Used as a short-term solution for acute muscle issues, allowing for targeted and effective symptom management.

In the case of an overdose of tolperisone 50mg tablets, several symptoms may occur, including drowsiness, dizziness, and potentially severe respiratory depression. The severity of the overdose effects can vary depending on the individual's health and the amount ingested. It is crucial to seek medical advice promptly if an overdose is suspected, as professional guidance can help manage any adverse reactions and prevent potential complications. Timely intervention and monitoring are essential to ensure the patient's well-being.

In the case of a missed dose of tolperisone 50mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to get back on track with your medication regimen safely. It is generally recommended to take the missed dose as soon as possible, but do not take more than one dose in a single day.

To take the tolperisone 50mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, exactly as prescribed by your healthcare professional, typically one to three times a day, or follow the instructions provided by your pharmacist.

Following are the circumstances when Tolperisone 50mg Tablet should be avoided:

• Should not be taken by individuals with a known allergy to Tolperisone or other related muscle relaxants.
• Not suitable for patients with severe liver or kidney disease.
• Contraindicated in individuals with myasthenia gravis (a neuromuscular disorder).
• Should not be used in patients with a history of acute porphyria (a metabolic disorder).
• Avoid in cases of gastrointestinal obstruction or severe gastrointestinal disorders.
• Not recommended for individuals with a history of prolonged QT interval (a heart rhythm disorder).

The side effects of Tolperisone 50mg Tablet may include:

• Dry mouth
• Dizziness or drowsiness
• Fatigue or weakness
• Nausea and vomiting
• Stomach pain or cramps
• Skin rashes or itching
• Allergic reactions (e.g., swelling, difficulty breathing)
• Muscle stiffness or tremors

Following are the precautions and warnings for tolperisone 50mg Tablet:

• Not recommended for individuals with known allergies to tolperisone or other similar muscle relaxants.
• Patients with liver or kidney disease should use with caution, as the dosage may need adjustment.
• Elderly patients may be more sensitive to the effects and should be monitored closely for adverse reactions.
• Avoid driving or operating heavy machinery as it may cause drowsiness or dizziness.
• Not recommended for children and adolescents under 18 years of age.
• Inform your doctor if you have a history of epilepsy or other seizure disorders before taking this medication.
• Tolperisone may interact with other medications; inform your healthcare provider about all the medicines you are currently taking.
• Do not abruptly stop taking this medication without consulting your doctor, as it may lead to withdrawal symptoms.

Following are the drug interactions for tolperisone 50mg Tablet:

• Alcohol consumption should be avoided as it may enhance the sedative effects of tolperisone.
• Tolperisone may interact with certain antidepressants like SSRIs and tricyclic antidepressants, leading to increased side effects such as drowsiness and dizziness.
• It can increase the effects of other central nervous system depressants, including opioids and benzodiazepines, potentially causing excessive sedation.
• Antihistamines taken together with tolperisone may result in additive drowsiness and impaired alertness.
• The effects of muscle relaxants and tolperisone can be additive, requiring close monitoring for respiratory depression.
• Tolperisone may interact with certain antibiotics, affecting its metabolism and potentially increasing side effects.
• Caution is advised when using tolperisone with drugs that affect liver enzymes, as it may alter the drug's metabolism.

Following are the food interactions for Tolperisone 50mg Tablet:

• Tolperisone may cause dry mouth, so chewing sugar-free gum or sucking on sugar-free candies can help alleviate this symptom.
• Avoid consuming grapefruit or grapefruit juice as it can interfere with the metabolism of the drug and increase its concentration in the body.
• Alcohol should be avoided as it can increase the risk of side effects such as drowsiness and dizziness, and may also intensify the muscle relaxant effect of tolperisone.
• Caffeine intake should be limited as it can counteract the relaxing effects of tolperisone and potentially cause restlessness.
• There is no specific dietary restriction, but maintaining a well-balanced diet can support overall health and muscle function.
• Staying hydrated by drinking plenty of water is essential, especially if experiencing dry mouth as a side effect.
• Consuming potassium-rich foods like bananas, oranges, and spinach may be beneficial as tolperisone can cause low potassium levels in some cases.

Tolperisone 50mg Tablets should be stored in a cool and dry place, preferably in a tightly sealed container to maintain their integrity. The ideal storage temperature is between 68°F and 77°F (20°C and 25°C), so avoid extreme temperatures and direct sunlight. It is crucial to keep the tablets away from moisture, so do not store them in the bathroom or kitchen, where humidity can affect their quality. Always check the expiration date, and if the tablets are expired or no longer needed, proper disposal is essential. Do not throw them into the trash or flush them down the toilet; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for tolperisone 50mg Tablet:

• Take the tablet as directed by your doctor, usually 2-3 times a day.
• Swallow the tablet whole with a full glass of water.
• It can be taken with or without food, but taking it with food may prevent stomach upset.
• Do not crush, chew, or break the tablet, as it may affect its effectiveness.
• If you have difficulty swallowing, ask your pharmacist for advice on alternative forms.
• Avoid alcohol consumption while taking this medication as it may increase side effects.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.