Myonan (50mg) 100 Tablets

Mebendazole 50mg Tablet's primary mechanism of action is through its interference with the microtubule system in helminthic parasites. It binds to the colchicine-sensitive site of tubulin, disrupting the assembly of microtubules, which are essential for energy transport, mobility, and reproduction in the parasites. This disruption leads to a decrease in glucose uptake, resulting in a depletion of glycogen stores and subsequent death of the helminths. Mebendazole specifically targets the larval and adult stages of the parasites, causing paralysis and eventual elimination from the host's body. The drug's selective toxicity towards these parasites is due to its higher affinity for the parasitic tubulin compared to that of the host.

Mebendazole 50mg

Anthelmintic.

Tablet

The following are the uses of Mebendazole 50mg Tablet:

• Used for treating roundworm, hookworm, whipworm, and pinworm infestations.
• Used for managing ascariasis and enterobiasis.
• Used to eliminate threadworms and other common worm infections.
• Used to control parasitic infections affecting the digestive system.
• Used for preventing and controlling gastrointestinal worm infections.
• Used for treating multiple worm infections simultaneously.
• Used to eradicate worms and improve digestive health.
• Used for both children and adults with worm-related issues.

In the case of an overdose of Mebendazole 50mg Tablets, the symptoms may include dizziness, headache, nausea, and vomiting. The severity of the symptoms can vary depending on the amount ingested. It is important to seek medical advice promptly if an overdose is suspected. Treatment for overdose may involve managing the symptoms and providing supportive care to ensure the individual's well-being. Prompt medical intervention can help mitigate potential complications.

In the case of a missed dose of Mebendazole 50mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to proceed, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely.

To take Mebendazole 50mg Tablets, swallow the tablet whole with a full glass of water, preferably with a meal or as directed by your healthcare professional, typically twice a day, 7 days apart, to ensure effective treatment.

Here are the conditions or situations when Mebendazole 50mg Tablet should not be taken:

• Avoid using if you have a known allergy to Mebendazole or similar medications.
• Not suitable for individuals with liver problems or diseases.
• Contraindicated in patients with blood disorders or abnormal blood cell counts.
• Should not be taken if you have a known sensitivity to benzimidazole compounds.
• Not recommended for individuals with severe intestinal conditions or bowel obstructions.
• Avoid using if you have a history of seizures or epilepsy.
• Not suitable for pregnant women or women who are breastfeeding.
• Should not be given to children under 2 years of age without medical advice.
• Contraindicated in individuals with known or suspected intestinal perforation.

The side effects of Mebendazole 50mg Tablet may include:

• Headache
• Dizziness
• Nausea and vomiting
• Diarrhea or constipation
• Abdominal pain
• Skin rash or itching
• Temporary hair loss
• Fever

Following are the precautions and warnings for Mebendazole 50mg Tablet:

• Do not use in patients with known hypersensitivity or allergy to Mebendazole or any of its components.
• Mebendazole should be used with caution in individuals with liver disease, as it is primarily metabolized in the liver. Regular monitoring of liver function is advised.
• This medication is not recommended for pregnant women, especially during the first trimester, unless the potential benefits outweigh the risks. Effective contraception is advised for women of childbearing age.
• Mebendazole passes into breast milk, so breastfeeding should be avoided while using this medication.
• Elderly patients may be more susceptible to the side effects of Mebendazole; therefore, close monitoring is recommended.
• Patients with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption should not take this medication, as it contains lactose.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Mebendazole 50mg Tablet:

• Mebendazole may decrease the effectiveness of oral contraceptives, requiring additional birth control methods.
• Taking Mebendazole with metronidazole can result in a severe disulfiram-like reaction, including nausea, vomiting, and headaches.
• The absorption of Mebendazole can be reduced by antacids, potentially decreasing its effectiveness.
• The metabolism of Mebendazole is inhibited by cimetidine, leading to increased Mebendazole levels in the body.
• Rifampicin induces liver enzymes, which can accelerate the metabolism of Mebendazole, reducing its effectiveness.
• Carbamazepine may decrease Mebendazole levels, potentially reducing its therapeutic effect.
• The concurrent use of Mebendazole and dexamethasone can lead to increased dexamethasone concentrations in the body.

Following are the food interactions for Mebendazole 50mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can interfere with Mebendazole's metabolism, leading to increased drug levels and potential side effects.
• Alcohol intake is not recommended as it may reduce the effectiveness of Mebendazole and increase the risk of liver-related issues.
• Fatty foods can slow down the absorption of Mebendazole, so it is advisable to take the medication on an empty stomach for better absorption.
• Avoid eating brie cheese, camembert cheese, and blue cheese during treatment as they may contain mold that can interact with Mebendazole.
• Dairy products like milk and yogurt can hinder the absorption of Mebendazole, so it's best to separate them by a few hours.
• Avoid consuming large amounts of black pepper as it may affect the metabolism of Mebendazole.
• Vitamin C-rich foods like oranges, lemons, and broccoli may reduce the effectiveness of Mebendazole, so consume them in moderation.
• Always follow the dosage instructions provided by your healthcare professional for optimal results.

Mebendazole 50mg Tablets should be stored in a secure and dry location, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It's crucial not to expose the medication to extreme temperatures, so avoid storage in places like bathrooms, near stoves, or on radiators. Always verify the expiration date on the packaging; if the tablets are past their prime or no longer needed, do not flush them or pour them down the drain. Instead, consult a pharmacist or healthcare professional for safe disposal instructions. Lastly, ensure the medication is kept out of children's reach to prevent unintended consumption.

Following are the quick tips for Mebendazole 50mg Tablet:

• Take the tablet as directed by your doctor, usually once or twice a day.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Mebendazole is best taken on an empty stomach, 1 hour before or 2 hours after meals.
• Complete the full course of medication as prescribed, even if symptoms disappear.
• Avoid alcohol consumption during treatment as it may reduce the effectiveness of the medicine.
• Store the medicine in a cool, dry place, away from direct sunlight and moisture.
• Consult your doctor if you experience any severe or persistent side effects.