MYOPLEX SACHETS (10S)

Folic acid, also known as vitamin B9, primarily acts by supporting the body's synthesis of DNA, RNA, and certain amino acids. Its mechanism of action revolves around its role as a coenzyme in various metabolic processes. When administered, folic acid is converted into its biologically active form, tetrahydrofolate (THF), which serves as a cofactor for enzymes involved in one-carbon transfers. These reactions are essential for the synthesis of purines and pyrimidines, the building blocks of DNA and RNA. By ensuring an adequate supply of THF, folic acid promotes the normal development and function of cells, particularly during periods of rapid cell division, such as in pregnancy and early childhood. THF also plays a role in the conversion of homocysteine to methionine, which is crucial for maintaining healthy homocysteine levels and cardiovascular health.

Folic Acid

Vitamin supplement.

Sachet

The following are the uses of Folic Acid Sachet:

• Used for preventing and treating low blood levels of folic acid.
• Used for maintaining healthy blood cells and reducing the risk of neural tube birth defects in pregnancy.
• Used for supporting proper brain function and mental health.
• Used for promoting healthy skin, hair, and nails.
• Used for aiding in the metabolism of proteins and the formation of red blood cells.
• Used for assisting in the absorption and utilization of certain nutrients like vitamins B12 and C.
• Used for supporting overall growth and development in children.
• Used for contributing to a healthy immune system.

In the case of an overdose of Folic Acid Sachets, it is important to remain calm and seek medical advice promptly. While folic acid is generally considered safe, excessive consumption may lead to symptoms such as nausea, stomach upset, and sleep disturbances. If you suspect an overdose, contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the amount ingested and individual factors.

In the case of a missed dose of Folic Acid Sachet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your dosage and ensure you're receiving the appropriate amount of folic acid. It is essential to maintain a consistent dosing schedule for the best results.

To use the Folic Acid Sachet, empty the contents of the sachet directly onto your tongue or mix it with a small amount of water or juice, and then swallow it without chewing, once daily or as directed by your healthcare professional.

Following are the circumstances where Folic Acid Sachet should be avoided:

• Must not be used in individuals with a known allergy or hypersensitivity to Folic Acid or any of its excipients.
• Not suitable for individuals who have an adequate or high level of folate in their blood.
• Should be avoided in people with untreated or undiagnosed anemia.
• Contraindicated in patients with certain types of anemia, such as pernicious anemia or megaloblastic anemia due to vitamin B12 deficiency.
• Not recommended for individuals with a history of seizures or epilepsy, as high doses of Folic Acid may lower the effectiveness of anti-seizure medications.
• Avoid using Folic Acid sachets if you have a history of kidney stones, as excessive intake can increase the risk of kidney stone formation.
• Not suitable for people with certain rare genetic conditions, such as untreated anemias caused by folate metabolism disorders.

The side effects of Folic Acid Sachet may include:

• Nausea and vomiting
• Upset stomach or diarrhea
• Loss of appetite
• Sleep disturbances or insomnia
• Bitter or unpleasant taste in the mouth
• Allergic reactions, such as skin rash or itching
• Feeling of nervousness or irritability
• Constipation

Following are the precautions and warnings:

• Folic Acid Sachet should be used with caution in patients with a history of allergic reactions to vitamins or any of the excipients in the sachet.
• Patients with anemia should seek medical advice as the underlying cause may require further investigation and treatment.
• It is recommended to take folic acid supplements under medical supervision, especially during pregnancy, breastfeeding, or when planning a pregnancy.
• Do not exceed the recommended dosage, as high doses of folic acid may mask the symptoms of vitamin B12 deficiency, which can lead to neurological damage if left untreated.
• Individuals with malabsorption syndromes or gastrointestinal disorders may require higher doses or alternative forms of folic acid supplementation.
• Folic acid supplementation should not be used as a substitute for a balanced diet rich in natural sources of folate.
• Patients with a history of seizures or epilepsy should consult their healthcare provider before using this medication, as high doses of folic acid may interact with anticonvulsant medications.
• Keep out of reach of children and store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Folic Acid Sachet:

• Antiepileptic medications like phenytoin, phenobarbital, and primidone may reduce the effectiveness of folic acid.
• Folic acid can decrease methotrexate's toxicity, potentially reducing its effectiveness in cancer treatment.
• May interact with pyrimethamine, an antimalarial drug, reducing its efficacy in treating malaria.
• Sulfasalazine, used for inflammatory bowel disease, can decrease folic acid absorption.
• Antibiotics like tetracyclines may interfere with folic acid metabolism.
• Cholestyramine, a bile acid sequestrant, can reduce folic acid absorption.
• Zidovudine, an antiretroviral drug, may be less effective when taken with high doses of folic acid.

Following are the food interactions for Folic Acid Sachet:

• Folic acid absorption can be reduced by consuming tea, coffee, or carbonated beverages. It is advisable to avoid these drinks around the time of taking the supplement.
• Consuming alcohol while taking folic acid supplements should be minimized or avoided. Alcohol can interfere with the metabolism of folate and reduce its effectiveness.
• Dairy products, particularly milk, may decrease the absorption of folic acid. It is recommended to take the supplement at least one hour before or two hours after consuming milk or dairy-based products.
• Antacids containing calcium or magnesium can also reduce folic acid absorption. Maintain a gap of at least 2 hours between taking folic acid and antacids.
• Avoid excessive consumption of foods fortified with folic acid, such as certain breakfast cereals, as this can lead to overconsumption of the vitamin.
• Folic acid levels can be reduced by cooking, so it is beneficial to consume raw or lightly cooked vegetables to maximize folate intake.
• Ensure an adequate intake of vitamin B12 when supplementing with folic acid, as high doses of folic acid can mask a vitamin B12 deficiency, potentially leading to neurological issues.
• Folic acid may interact with certain medications, including methotrexate, phenytoin, and sulfasalazine, affecting their effectiveness. Always inform your healthcare provider about all medications you are taking.

The proper storage and disposal of Folic Acid Sachets are crucial for maintaining their effectiveness and safety. Store the sachets in a cool, dry area, preferably at room temperature, ensuring they are protected from direct sunlight and moisture. Keep the medication in its original packaging, tightly sealed, to prevent contamination. Avoid bathroom storage or placing it near heat sources like stoves or heaters, as temperature fluctuations can impact the sachet's integrity. Regularly check the expiration date, and if expired or no longer needed, dispose of the sachets properly. Avoid flushing or pouring them down the drain; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the sachets out of children's reach to prevent accidental consumption.

Following are the quick tips for Folic Acid Sachet:

• Always read the instructions on the sachet before use.
• Consume the contents of the sachet directly or mix with water/juice as directed.
• Take the sachet as a daily supplement or as advised by your doctor.
• Folic acid is essential for pregnant women to support fetal development.
• It can be taken at any time of the day, but consistency is key.
• Store the sachets in a cool, dry place, away from direct sunlight.
• Consult your healthcare provider if you have any specific medical conditions or concerns.