Myorel 4mg Tablet

Thiocolchicoside, the active ingredient in the 4mg tablet, acts as a muscle relaxant with anti-inflammatory and analgesic properties. Its primary mechanism of action involves binding to the gamma-aminobutyric acid (GABA) receptors in the central nervous system, particularly the GABAA receptor complex. By interacting with these receptors, thiocolchicoside modulates neuronal excitability, leading to muscle relaxation. This effect helps in reducing muscle spasms and associated pain. Additionally, thiocolchicoside may inhibit the release of inflammatory mediators, contributing to its anti-inflammatory action, although the exact mechanisms behind this effect are not yet fully understood.

Muscle relaxant.

Tablet

The following are the uses of Thiocolchicoside 4mg Tablet:

• Used for relieving muscle pain and stiffness, particularly in the neck and back.
• Used to treat muscle spasms and associated discomfort.
• Used to aid in the management of acute muscle injuries.
• Used to improve mobility and reduce inflammation in affected muscles.
• Used for post-operative pain and stiffness relief.
• Used to manage painful muscle contractions.
• Used for short-term relief of musculoskeletal pain.

Follow these dosage instructions:

• Adult Dosage

8 milligrams (mg) every 12 hours. Your doctor will determine the length of the treatment.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

In the case of an overdose of Thiocolchicoside 4mg Tablets, individuals may experience severe gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. Additionally, neurological effects like dizziness, confusion, and in severe cases, seizures, can occur. It is imperative to seek medical assistance promptly if an overdose is suspected, as early intervention can mitigate potential complications and ensure appropriate treatment is administered to manage the symptoms effectively.

In the case of a missed dose of Thiocolchicoside 4mg Tablet, it is generally advised to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen without compromising its effectiveness. It's important to maintain consistency with this medication for optimal results.

To take Thiocolchicoside 4mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, typically taken once or twice a day as directed.

Following are the conditions when Thiocolchicoside 4mg Tablet should not be used:

• Should not be taken if you are allergic to Thiocolchicoside or any other similar muscle relaxant medications.
• Contraindicated in individuals with known liver or kidney disease or impairment.
• Not suitable for children and adolescents under 16 years of age.
• Should not be used during pregnancy, especially during the first trimester, unless the potential benefits outweigh the risks.
• Contraindicated in women who are breastfeeding, as it may pass into breast milk.
• Should be avoided if you have a history of seizures or epilepsy, as it may lower the seizure threshold.
• Not recommended for individuals with a known blood disorder or those taking blood-thinning medications.
• Should not be used in patients with known stomach or intestinal ulcers or severe gastrointestinal conditions.
• Contraindicated in individuals with a history of porphyria, a rare metabolic disorder.

The side effects of Thiocolchicoside 4mg Tablet may include:

• Nausea and vomiting
• Dry mouth
• Dizziness
• Skin rashes or itching
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• Fatigue and weakness
• Gastrointestinal discomfort
• Muscle or joint pain

Following are the precautions and warnings for Thiocolchicoside 4mg Tablet:

• Avoid use in patients with known hypersensitivity to thiocolchicoside or any of its components.
• Not recommended for long-term use due to potential risks of genetic toxicity.
• Use with caution in patients with epilepsy or a history of seizures, as it may lower the seizure threshold.
• May cause drowsiness, dizziness, or impaired coordination; avoid driving or operating heavy machinery.
• Use with caution in patients with kidney or liver impairment, as metabolism and excretion may be affected.
• Not recommended for use in pregnant or breastfeeding women due to potential risks to the fetus or infant.
• Avoid exceeding the prescribed dose, as higher doses may increase the risk of serious adverse effects.
• May cause gastrointestinal disturbances such as nausea, vomiting, or diarrhea.
• Not intended for use in children unless prescribed by a healthcare provider.
• Should be used only under medical supervision for short-term treatment of muscle spasms.

Following are the drug interactions for Thiocolchicoside 4mg Tablet:

• Alcohol and other CNS depressants can increase the risk of drowsiness and sedation when taken with Thiocolchicoside.
• Anticoagulants like warfarin may have their effects enhanced, potentially leading to bleeding risks.
• Carbamazepine and phenytoin can reduce the plasma concentration of Thiocolchicoside, possibly reducing its efficacy.
• The muscle relaxant effect of Thiocolchicoside may be increased when combined with other neuromuscular blocking agents.
• It may interact with drugs metabolized by CYP3A4, potentially altering their effectiveness.
• Thiocolchicoside may increase the risk of arrhythmias when used with medications that prolong QT intervals.
• Concomitant use with oral contraceptives may reduce the effectiveness of the contraceptive method.

Following are the food interactions for Thiocolchicoside 4mg Tablet:

• Avoid consuming grapefruit or grapefruit juice as it may alter the drug's metabolism and increase the risk of side effects.
• Alcohol consumption should be limited or avoided as it can enhance the sedative effects of Thiocolchicoside, leading to increased drowsiness and dizziness.
• High-fat meals may slightly delay the absorption of the medication, but it does not significantly impact its effectiveness.
• Caffeine-rich beverages like coffee or energy drinks should be consumed in moderation as they may counteract the muscle relaxant effects of Thiocolchicoside.
• Avoid spicy foods as they may irritate the digestive system and potentially affect the absorption of the medication.
• Dairy products like milk or yogurt should be consumed with caution as they can form complexes with Thiocolchicoside, reducing its bioavailability.
• Consuming large amounts of fiber-rich foods like whole grains and legumes around the time of medication intake may decrease its absorption.
• Always ensure you stay well-hydrated while taking Thiocolchicoside to support overall kidney function and aid in the elimination of the drug from the body.

Thiocolchicoside 4mg Tablets should be stored in a cool, dry area, ideally between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, and keep them in their original packaging or a tightly sealed container. Always check the expiration date before using the medication and do not use if it has expired. When disposing of unused or expired tablets, do not throw them into the garbage or flush them down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for guidance on safe disposal methods. Keep the medication away from children and pets to prevent accidental ingestion, as it can be harmful if consumed without medical supervision.

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Following are the quick tips for Thiocolchicoside 4mg Tablet:

• Consult your doctor or pharmacist for personalized instructions based on your medical condition.
• Ensure you understand the dosage and duration prescribed by your healthcare provider.
• Swallow the tablet whole with a full glass of water, preferably at the same time each day.
• Take the medication as directed; do not crush, chew, or break the tablet.
• Avoid consuming alcohol while taking this medication as it may increase side effects.
• Inform your doctor about all medications you're taking to prevent potential interactions.
• If you experience any severe side effects, contact your healthcare provider immediately.
• Store the medication at room temperature, away from moisture and direct sunlight.