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Product Information
Rifampin is thought to inhibit bacterial DNA-dependent RNA polymerase, which appears to occur as a result of drug binding in the polymerase subunit deep within the DNA/RNA channel, facilitating direct blocking of the elongating RNA. The known mode of action of isoniazid (INH) is to inhibit bacterial cell wall synthesis following activation by the bacterial catalase–peroxidase enzyme KatG in Mycobacterium tuberculosis. Ethambutol exerts its bacteriostatic activity by virtue of inhibition of arabinosyl transferase which is an enzyme necessary for the synthesis of bacterial cell wall
Antibiotic
Used in combination or alone to treat tuberculosis
To be used as per doctor's prescription
Acute poisoning due to isoniazid, ethambutol and rifampicin overdose is often associated with generalized tonic-clonic seizures, altered sensorium, renal, hepatic dysfunctions, and severe metabolic acidosis. Adverse effects such as pruritus, joint pain, gastrointestinal upset, abdominal pain, malaise, headache, dizziness, mental confusion, disorientation, and possible hallucinations can also occur. Seek immediate help in case of overdose
Try not to miss a dose. If you miss a dose, take it as soon as you can. Then continue your normal schedule. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Use and dosage must be determined by the doctor
Do not use in case of:
Common side effects incllude:
Cautions include:
This medication may interact with these drugs:
Store in a cool, dry place away from sunlight. Keep away from children
No
Do not self-medicate
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