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Nagra (250mg) 10 Capsules
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- Manufacturer Medisearch Pharma (Pvt.) Ltd.
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Generic Name
Azithromycin 250mg
Healthwire Pharmacy Ratings & Reviews (1500+)
4.9/
5
Delivery by Today, 09:00 am - 12:00 pm
Product Information
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Description
Azithromycin; It is of Semi Synthetic origin and belongs to the Azalide group. It belongs to the antibacterial (Protein synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in antibiotics pharmacological group. Azithromycin interferes with protein synthesis in bacteria and in this way it prevents bacterial growth. It works by binding to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA while nucleic acid synthesis is not affected. Oral absorption of Azithromycin is found to be 34% ±19. Volume of distribution is found to be 31.1 U/kg and plasma protein binding is 51%. Renal Excretion accounts for < 10% and plasma half-life is 68%. -
Ingredients
Azithromycin 250mg
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Dosage Form
Capsule
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Uses
Azithromycin is utilized for the following therapeutic indications:
- Treatment of respiratory infections (e.g., pneumonia, bronchitis)
- Management of skin and soft tissue infections
- Treatment of sexually transmitted infections (e.g., chlamydia, gonorrhea)
- Treatment of otitis media (middle ear infections)
- Management of pharyngitis and tonsillitis
- Prophylaxis against endocarditis in high-risk patients
- Treatment of sinusitis
- Management of Mycobacterium avium complex (MAC) infections
- Efficacy against atypical pathogens (e.g., Mycoplasma, Chlamydia)
- Treatment of pelvic inflammatory disease (PID) when used in combination therapy
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Dosage
Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. Adult dose: 500mg once daily or 250mg twice daily For typhoid fever, the dose is 500mg to 1000mg once daily for 5-7 days. Oral dose for Infants, Children over 6 months, and Adolescents: 5 to 12 mg/kg/dose, typically administered as 10 to 12 mg/kg/dose on a day while usual maximum dose is 500mg/dose Followed by 5-6 mg/kg once daily (usual maximum dose: 250 mg/dose). -
In case of Overdose
Consult your doctor in case of overdose. The typical symptoms of an overdose with macrolide antibiotics include reversible loss of hearing, severe nausea, vomiting and diarrhea. In the event of overdose, the administration of medicinal charcoal and general symptomatic treatment and supportive measures are indicated as required. -
Missed Dose
If you miss any dose then take the dose as soon as you remember, but if it's the time for the next dose then do not double the dose. -
How To Use
Take it orally according to your doctor's instructions. -
When Not to Use
Azithromycin is contraindicated in conditions like; hepatic impairment and hypersensitivity to this drug. This drug should not be given to Pregnant ladies, patients suffering from kidney dysfunction and neonates as it may cause high risks. -
Side Effects
Dizziness Vertigo Headache Fatigue Nausea Vomiting Palpitation Abdominal pain Rashes Photosensitivity GI disturbance Azithromycin can prolong the QTc interval (heart rhythm abnormality). -
Precautions & Warnings
Azithromycin should be used with caution in patients with any allergy, especially allergies to drugs, liver disease, jaundice, history of colitis, stomach problems or kidney disease. This drug should be used only if clearly needed during pregnancy or lactation. -
Food Interactions
Tablets should be taken with food to avoid GI upset. While extended release formulation could be taken in an empty stomach. -
Storage/Disposal
Store below 30°C. Protect from sunlight, heat and moisture.
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