Namenda (5mg) 60 Tablets

Memantine 5mg Tablet primarily acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It binds to and modulates the NMDA receptors, which are crucial for synaptic plasticity and excitatory neurotransmission in the brain. By blocking the excessive activation of NMDA receptors, memantine regulates the influx of calcium ions into neurons. This mechanism helps restore the balance between glutamate and GABA neurotransmission, which is often disrupted in neurodegenerative conditions. Memantine's action is believed to enhance cognitive function and provide neuroprotective effects by reducing excitotoxicity and stabilizing neuronal function.

NMDA receptor antagonist

Tablet

The following are the uses of Memantine 5mg Tablet:

• Used for treating moderate to severe dementia caused by Alzheimer's disease.
• Used to improve memory, awareness, and the ability to perform daily functions.
• Used to regulate glutamate, an essential brain chemical for learning and memory.
• Used to enhance cognitive function and overall brain health.
• Used for patients with moderate to severe Alzheimer's who show specific symptoms.
• Used to slow down the progression of symptoms and improve quality of life.
• Used as a part of a comprehensive treatment plan for Alzheimer's management.
• Used under medical supervision, with regular monitoring for effectiveness.

In the case of an overdose of Memantine 5mg Tablets, individuals may experience a range of symptoms including dizziness, confusion, headaches, and in severe cases, seizures or loss of consciousness. It is important to seek medical advice promptly if an overdose is suspected. Treatment for overdose may involve supportive care, monitoring vital signs, and managing symptoms until the excess medication is cleared from the body. Prompt action can help mitigate potential health risks associated with overdosing on this medication.

In the case of a missed dose of Memantine 5mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss several doses, contact your healthcare provider for guidance on how to safely resume your medication, as they may provide specific instructions based on your medical condition and treatment plan.

To take Memantine 5mg Tablet, place the tablet in your mouth and swallow it whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Following are the conditions when Memantine 5mg Tablet should not be used:

• Avoid using this medication if you have a known allergy to Memantine or any other similar drugs.
• Do not take this medication if you have severe kidney disease or severe liver impairment.
• Not suitable for patients with severe dementia or other cognitive disorders.
• Contraindicated in individuals with a history of seizures or epilepsy.
• Should not be used to treat conditions like delirium or hallucinations.
• Not recommended for individuals with severe hypertension (high blood pressure).
• Do not administer this medication to patients with severe urinary retention issues.

The side effects of Memantine 5mg Tablet may include:

• Dizziness
• Headache
• Confusion
• Constipation
• Nausea and vomiting
• Loss of appetite
• Increased blood pressure
• Hallucinations (seeing or hearing things that are not there)

Following are the precautions and warnings for Memantine 5mg Tablet:

• Do not start or continue Memantine if you have a known allergy to Memantine or any other ingredients in the tablet.
• Patients with kidney issues should exercise caution, as dosage adjustments may be necessary based on the level of kidney impairment.
• This medication may cause dizziness or drowsiness, so caution is advised when performing tasks that require alertness, such as driving or operating machinery.
• Avoid alcohol consumption while taking Memantine, as it may exacerbate side effects.
• Inform your healthcare provider about all medications you are currently taking to prevent potential drug interactions.
• Patients with epilepsy or seizure disorders should use Memantine with caution, as it may lower the seizure threshold.
• Pregnant and breastfeeding women should consult their doctor before taking Memantine, as its effects on the fetus and infant are not fully established.
• Store Memantine at room temperature, away from direct sunlight and moisture, and keep it out of reach of children and pets.

Following are the drug interactions for Memantine 5mg Tablet:

• Memantine can interact with anticholinergic medications like oxybutynin, potentially leading to increased side effects such as confusion, constipation, and dry mouth.
• It may reduce the effectiveness of quinolone antibiotics like ciprofloxacin, and adjustments in dosage or monitoring may be required.
• Concomitant use with other NMDA receptor antagonists (e.g., amantadine, ketamine) can result in excessive NMDA receptor blockade, causing increased side effects and altered cognitive function.
• Memantine may increase the risk of seizures when used with anticonvulsant medications, and close monitoring is advised.
• Drugs that increase gastric pH (e.g., proton pump inhibitors, H2 blockers) may reduce the absorption of memantine, potentially requiring dosage adjustments.
• Memantine can interact with certain antidepressants, such as SSRIs and tricyclic antidepressants, leading to increased side effects and altered therapeutic effects.
• Caution is advised when combining Memantine with other centrally acting drugs, as it may enhance their effects and increase the risk of adverse reactions.

Following are the food interactions for Memantine 5mg Tablet:

• Avoid consuming alcohol while taking this medication as it can impair your thinking and reactions, and may worsen side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Memantine, potentially leading to increased drug levels in the body.
• Caffeine intake should be monitored as Memantine may increase caffeine's effects, resulting in nervousness, anxiety, and increased heart rate.
• Avoid taking herbal supplements like St. John's Wort as it may reduce the effectiveness of Memantine.
• Do not eat large meals just after taking the medication, as it may interfere with the absorption of Memantine. Instead, take the medicine on an empty stomach.
• Avoid consuming foods high in tyramine (aged cheeses, cured meats, fermented foods) as Memantine may interact with tyramine, leading to increased blood pressure.
• Always follow the dosage instructions provided by your healthcare professional, and inform them about any dietary concerns or potential interactions.
• Maintain a balanced diet and stay hydrated while taking Memantine to ensure optimal health and medication effectiveness.

Memantine 5mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct exposure to sunlight, heat, or moisture. It is crucial to store the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Always check the expiration date before using the medication, and dispose of any unused or expired tablets responsibly. Do not dispose of them in sinks, toilets, or drains; instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods. Keep the medication out of children's reach to prevent accidental consumption. Remember, proper storage and disposal practices are essential for the safety and effectiveness of Memantine tablets.

Following are the quick tips for Memantine 5mg Tablet:

• Take the tablet as directed by your doctor, typically once or twice daily.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Take it at the same time(s) each day to maintain consistent blood levels.
• Do not stop taking Memantine without consulting your doctor, even if you feel better.
• Inform your doctor about all medications you are taking to avoid potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• If you miss a dose, take it as soon as you remember, unless it's close to your next dose; do not double the dose to catch up.