Nassa (30mg) 20 Tablets

Nassa (30mg) 20 Tablets

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  • Manufacturer GENETICS PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Mirtazapine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Mirtazapine, a medication commonly prescribed as a 30mg tablet, primarily exerts its therapeutic effects through the modulation of neurotransmitters in the brain. Its mechanism of action involves blocking specific serotonin receptors (5-HT2 and 5-HT3 receptors), which increases the release of serotonin and norepinephrine, two key neurotransmitters involved in mood regulation. Moreover, mirtazapine's unique ability to antagonize certain adrenergic and histaminergic receptors contributes to its sedative properties, often resulting in improved sleep for individuals taking this medication. This dual action on neurotransmitter systems is thought to underlie mirtazapine's effectiveness in treating various psychiatric conditions, particularly depression and anxiety disorders.

  • Ingredients

    Mirtazapine
  • Drug Class

    Antidepressant (tetraycyclic).

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Mirtazapine 30mg Tablet:

    • Used for treating major depressive disorder in adults, providing relief from symptoms like persistent sadness and loss of interest.
    • Used for improving mood, sleep, appetite, and energy levels in patients with depression.
    • Used to restore the balance of certain natural substances (neurotransmitters) in the brain, enhancing overall mental well-being.
    • Used to help individuals with depression regain a positive outlook and a sense of calm, aiding in their daily functioning.
    • Used to alleviate feelings of anxiety and restlessness associated with depression, promoting a more relaxed state.
    • Used for managing weight loss or gain and sleep disturbances caused by depression, aiding in overall health and recovery.
    • Used to support patients in their journey towards improved mood and emotional stability, under the guidance of a healthcare professional.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Depression • Recommended dosage is 15-45 mg daily
    • Anxiety • Recommended dosage is 15-30 mg daily
    • Insomnia • Initial dosage is 30-45 mg taken at bedtime
  • In case of Overdose

    In the case of an overdose of Mirtazapine 30mg Tablets, individuals may experience a range of symptoms, including severe drowsiness, confusion, and difficulty maintaining balance. Other signs may include an increased heart rate, dilated pupils, and potential seizures. It is important to note that the severity of these symptoms can vary based on the amount ingested and individual factors. Prompt medical intervention is necessary to manage any potential complications and ensure the well-being of the person involved.

  • Missed Dose

    In the case of a missed dose of Mirtazapine 30mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed multiple doses, consult your healthcare provider for advice on how to get back on track with your medication regimen. It is generally recommended to take the missed dose within a 12-hour window from the time it was originally scheduled.

  • How To Use

    To take Mirtazapine 30mg Tablets, swallow the tablet whole with a glass of water, preferably in the evening before bedtime, following the dosage instructions provided by your healthcare professional, typically starting with a lower dose and gradually increasing as directed.

  • When Not to Use

    Here are the conditions and situations when Mirtazapine 30mg Tablet should not be taken:

    • Should not be used in individuals with a known allergy to Mirtazapine or any of its components.
    • Contraindicated in patients with a history of severe liver or kidney disease.
    • Not recommended for individuals with a history of seizures or epilepsy.
    • Should be avoided in patients with severe respiratory depression or severe breathing disorders.
    • Contraindicated during the acute recovery period after a heart attack.
    • Not suitable for individuals with severe blood disorders, such as low white blood cell count or bone marrow depression.
    • Should not be used in patients with severe hypertension that is not well-controlled.
    • Contraindicated in patients with severe glaucoma.
    • Should be used with caution and avoided if possible in elderly patients with dementia, as it may increase the risk of confusion and agitation.
    • Mirtazapine should not be combined with other medications that have a strong sedative effect, as it may cause excessive drowsiness.
  • Side Effects

    The side effects of Mirtazapine 30mg Tablet may include:

    • Increased appetite and weight gain
    • Drowsiness or sedation
    • Dry mouth
    • Dizziness
    • Constipation
    • Blurred vision
    • Confusion or disorientation
    • Increased cholesterol levels
  • Precautions & Warnings

    Following are the precautions and warnings for Mirtazapine 30mg Tablet:

    • This medication can cause drowsiness and impaired judgment; avoid driving or operating heavy machinery until you know how it affects you.
    • Do not consume alcohol while taking Mirtazapine, as it may intensify the sedative effects.
    • Mirtazapine may cause suicidal thoughts or actions in some individuals, especially in the initial stages of treatment. Monitor for any changes in mood or behavior.
    • Elderly patients may be more sensitive to the side effects; regular monitoring is recommended.
    • Patients with a history of seizures, heart problems, or liver disease should use Mirtazapine with caution and under medical supervision.
    • If you have a history of narrow-angle glaucoma, this medication should be used with caution and regular eye examinations.
    • Discontinuation of Mirtazapine should be gradual to minimize withdrawal symptoms; do not stop abruptly.
  • Drug Interactions

    Following are the drug interactions for Mirtazapine 30mg Tablet:

    • Avoid combining with other antidepressants like SSRIs, SNRIs, or MAOIs, as it may lead to serotonin syndrome, a serious condition.
    • Mirtazapine can increase the effects of sedatives and opioids, potentially causing excessive drowsiness and respiratory depression.
    • The drug may reduce the effectiveness of blood pressure medications, requiring close monitoring of blood pressure.
    • Consumption of alcohol with Mirtazapine can enhance sedation and impair cognitive functions.
    • It may increase the blood levels of certain anticonvulsants and antipsychotics, leading to increased side effects.
    • Mirtazapine can interact with anticoagulants, possibly requiring adjustments in dosage to maintain therapeutic effects.
    • Use with caution when taking medications that affect liver enzymes, as this may alter Mirtazapine's metabolism.
  • Food Interactions

    Following are the food interactions for Mirtazapine 30mg Tablet:

    • Avoid consuming grapefruit and grapefruit juice as they can increase the drug concentration in the blood by inhibiting the enzyme CYP2D6, potentially leading to increased side effects.
    • Alcohol consumption should be minimized or avoided as it may enhance the sedative effects of Mirtazapine, increasing the risk of dizziness and drowsiness.
    • Foods high in tyramine (aged cheeses, cured meats, fermented foods) should be limited as Mirtazapine can potentially interact with tyramine, leading to increased blood pressure.
    • Mirtazapine may cause increased appetite and weight gain, so monitoring calorie intake and maintaining a balanced diet is essential.
    • Avoid high-fat meals as they may slightly reduce the absorption of Mirtazapine, although this effect is not clinically significant.
    • Patients with diabetes should be cautious as Mirtazapine can affect blood sugar levels, and dietary adjustments might be necessary.
    • No specific food restrictions are required, but maintaining a healthy diet is generally recommended during Mirtazapine therapy.
    • Always consult your healthcare provider for personalized dietary advice while taking Mirtazapine.
  • Storage/Disposal

    Mirtazapine 30mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original packaging or a designated storage container to maintain their integrity. Ensure the storage area is out of reach of children and pets to prevent accidental consumption. When disposing of unused or expired Mirtazapine tablets, do not throw them in the trash or flush them down the toilet. Instead, contact your pharmacist or local waste management authority for guidance on proper disposal methods, as these may vary depending on your region. It is essential to handle and dispose of medications responsibly to minimize potential environmental impact and prevent unauthorized access.

  • Quick Tips, if any

    Following are the quick tips for Mirtazapine 30mg Tablet:

    • Consult your doctor before starting this medication and discuss your medical history.
    • Take the tablet as directed by your doctor, usually once daily.
    • It can be taken with or without food, but taking it with food may prevent stomach upset.
    • Swallow the tablet whole, do not crush or chew.
    • Avoid alcohol as it may increase side effects.
    • Do not stop taking the medication without consulting your doctor.
    • Store the tablets at room temperature, away from light and moisture.
  • Laboratory Screening

    Mirtazapine is a medication that can interact with various lab tests, therefore, it is crucial to inform your doctor if you are taking this medication to avoid unintended interactions with lab results. Your doctor will likely order lab tests to monitor your liver, kidneys, thyroid, and to check your blood cell and cholesterol levels in order to ensure no unexpected changes in your health occur. Low blood cell counts and high cholesterol levels have been observed in some patients taking mirtazapine, which is why it is important to monitor your levels regularly. These tests help ensure that mirtazapine is not causing unwanted changes to your overall health. It is important to express any concerns you may have regarding your health and any medications you take so your doctor can determine if any lab tests are needed to address those concerns.

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