Natacin (5.0%) 5ml Eye Suspension

Natamycin, the active ingredient in Natamycin Eye Syrup/Suspension, is a broad-spectrum antifungal agent that specifically targets fungal cell membranes. Its mechanism of action involves binding to ergosterol, a key component of fungal cell membranes, which results in the formation of large, aqueous-filled pores. These pores disrupt the integrity of the fungal cell membrane, leading to the leakage of vital intracellular components and subsequent cell death. Natamycin is highly effective against a wide range of fungi, including Aspergillus, Candida, and Fusarium species, by directly interfering with the structure and function of their cell membranes.

Macrolide antifungal drug

Capsule

The following are the uses of Natamycin Eye Syrup/Suspension:

• Used for treating fungal infections of the eye, particularly those caused by Fusarium species.
• Used for preventing fungal contamination in eye injuries or post-surgery.
• Used for treating corneal ulcers associated with fungal infections.
• Used for managing fungal keratitis, ensuring effective eye treatment.
• Used for relieving symptoms like redness, itching, and discharge in fungal eye infections.
• Used for maintaining eye health during fungal infection treatment.
• Used for promoting healing and preventing further eye damage.

In the case of an overdose of Natamycin Eye Syrup/Suspension, it is unlikely to cause significant harm. However, if a large amount is ingested, it may lead to temporary gastrointestinal discomfort or nausea. In such instances, it is advisable to seek medical advice for appropriate guidance and support. The eye suspension is typically well-tolerated, and its limited systemic absorption minimizes the risk of severe adverse effects.

In the case of a missed dose of Natamycin Eye Syrup/Suspension, it is important to administer the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed with your treatment.

To use Natamycin Eye Syrup/Suspension, gently shake the bottle, instill the prescribed number of drops into the affected eye(s), and follow the recommended dosing schedule provided by your healthcare professional, typically 1-2 drops every 1-2 hours, reducing the frequency as the infection improves.

Here are the situations when Natamycin Eye Syrup/Suspension should not be used:

• Avoid using if you have a known allergy or hypersensitivity to Natamycin or any other similar antifungal medication.
• Not recommended for individuals with a history of eye infections caused by viruses or bacteria.
• Do not use if you have a punctured or torn cornea.
• Contraindicated for patients with eye conditions such as conjunctivitis or uveitis.
• Not suitable for those with a history of eye surgery or eye trauma.
• Should not be used if you have a fungal infection in the eye that is not responsive to Natamycin.
• Avoid using if you have a history of eye irritation or inflammation after using antifungal eye drops.
• Not recommended for infants or children without medical advice.

The side effects of Natamycin Eye Syrup/Suspension may include:

• Eye irritation or redness
• Burning or stinging sensation in the eye
• Itchy eyes
• Swollen eyelids
• Blurred vision or temporary changes in vision
• Eye discharge
• Allergic reactions, such as skin rash or itching

Following are the precautions and warnings for Natamycin Eye Syrup/Suspension:

• This medication is for external use only and should not be ingested. Avoid contact with the mouth or eyes.
• Wash your hands before and after applying the medication to prevent contamination.
• Do not wear contact lenses while using Natamycin Eye Syrup/Suspension.
• Inform your doctor if you have any eye infections, injuries, or allergies before using this medication.
• Discontinue use and seek medical attention if you experience any signs of an allergic reaction, such as itching, redness, or swelling.
• Do not use the medication if the seal is broken or the solution appears discolored.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Natamycin Eye Syrup/Suspension:

• No known interactions with systemic medications, as minimal amounts of natamycin are absorbed into the bloodstream.
• Concomitant use with other ophthalmic medications is generally safe, but separate administration by at least 15 minutes is recommended to ensure proper retention and effectiveness of each medication.
• Antifungal drugs like amphotericin B and miconazole may have additive effects when used concurrently with natamycin, potentially increasing the risk of local side effects.
• Antibiotics such as neomycin and polymyxin B can interact, increasing the risk of corneal toxicity when used together.
• Combining with other corticosteroid eye drops may increase the risk of secondary infections and delay wound healing.
• Avoid using with contact lenses, as some lens materials may absorb the medication, reducing its effectiveness.
• Topical anesthetics should be used cautiously, as they may mask the symptoms of a more severe eye condition, and prolonged use can delay healing.

Following are the food interactions for Natamycin Eye Syrup/Suspension:

• Natamycin eye suspension is intended for ophthalmic use only, so there are no direct food interactions to consider.
• Avoid consuming alcohol during the course of treatment as it may cause temporary blurring or other changes in vision.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with some medications, although there is no direct interaction with Natamycin.
• Dairy products like milk and yogurt are generally safe and do not interfere with the effectiveness of Natamycin eye suspension.
• Consuming a balanced diet rich in vitamins, especially Vitamin A, C, and E, can support overall eye health during the treatment.
• There is no known interaction with caffeinated beverages, but moderation is advised to maintain overall eye comfort.
• Spicy foods are not known to interact with Natamycin, but they may cause temporary eye irritation or watering, which is not related to the medication.
• Always follow the dosage and administration instructions provided by your healthcare professional for optimal results.

Natamycin Eye Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication securely sealed in its original container to maintain its integrity and prevent contamination. Avoid storage in bathrooms or near heat-emitting appliances, as temperature fluctuations can impact the medicine's effectiveness. Always adhere to the expiration date on the packaging, and dispose of any unused or expired syrup responsibly; refrain from flushing it or pouring it down the drain. Consult your pharmacist or healthcare professional for guidance on appropriate disposal methods, and ensure that the medication is kept securely away from children to prevent accidental consumption.

Following are the quick tips for Natamycin Eye Syrup/Suspension:

• Wash your hands thoroughly before administering the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• Close your eyes gently after instilling the drops and apply light pressure to the inner corner of the eye for better absorption.
• If using other eye medications, wait at least 5-10 minutes before applying the next medication.
• Store the eye drops at room temperature, away from direct sunlight and heat.
• Do not use the eye drops if the solution changes color or becomes cloudy.