Nebil (2.5mg) 14 Tablets

Nebil (2.5mg) 14 Tablets

In-Stock 201 successful orders delivered in last 7 Days
  • Manufacturer Getz Pharma (Pvt.) Ltd.
  • Generic Name Nebivolol

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Storage/Disposal
  • Description

    Nebivolol is a unique selective β1 receptor blocker, used for treating hypertension, which works by blocking both β1 and β2 receptors, although the latter to a lesser degree. By inhibiting beta-adrenergic receptors, nebivolol reduces the heart rate and lowers blood pressure, as it prevents the activation of downstream signaling pathways that trigger contractions of the heart and blood vessels. This selective blocking action makes nebivolol particularly effective in treating hypertension, while also having a distinct and milder adverse effect profile compared to other non-selective beta-blockers. Nevertheless, it's important to note that nebivolol is not indicated for use in cases of cardiac arrest or complications associated with cardiac arrest.

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  • Ingredients

    Nebivolol
  • Drug Class

    Beta-Blocker

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treatment of high blood pressure
    • Treatment of chronic heart failure
    • May be used alongside other medications
    • Lower the risk of death from cardiovascular disease
    • Reduce the risk of stroke
    • Reduce the risk of heart attacks
    • Can be used in hypertension emergency room situations
    • Useful in preventing recurrent strokes
    • Lower heart rate
    • Wide therapeutic index
    • Acceptable tolerability profile

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • High blood pressure- 5–10 mg once daily
    • Heart failure- 5 mg once daily, may increase to 10 mg once daily if not adequately controlled
    • Dosage should always be prescribed by a physician and taken cautionary as per their advice.

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  • In case of Overdose

    Nebivolol is a drug that is used in the treatment of high blood pressure. If someone were to take too much Nebivolol, it is unlikely to be life-threatening, but certain adverse effects may be present. These effects include nausea, heartburn, or acid reflux, which may be counteracted with medications such as metoclopramide or omeprazole. Gastrointestinal effects are a common concern with Nebivolol overdoses and may lead to hospitalization if severe. Hypotension and syncope (fainting) can also occur, and intravenous fluids may be used to raise the patient's blood pressure. Bradycardia, or low heart rate, can be a concern, and atropine may be used to increase the heart rate. If the patient becomes hypotensive, vasopressors may be required. Liver injury and failure require close observation and additional treatment with N-acetylcysteine. Furthermore, skin reactions, excessive sweating, and chronic metabolic acidosis may occur and would need to be addressed by medical staff. It is important that the patient seeks emergency medical care if symptoms worsen to ensure proper and prompt treatment.

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  • Missed Dose

    Nevibolol is a prescription drug that should be used under medical supervision and according to the instructions provided by your doctor. If you have missed a dose, you should take it as soon as possible. However, if it is almost time for your next dose, it is advisable to skip the missed dose and continue with your regular schedule. Doubling up on your dose is not recommended as it can lead to overdose and other health complications. It is important to seek advice from a qualified medical professional like your doctor or pharmacist, who can provide guidance on the best course of action for your specific condition, based on your individual circumstances.

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  • How To Use

    Nebivolol is a prescription medication used to treat high blood pressure and heart-related conditions. It is a beta-blocker, and it works by reducing blood pressure by slowing the heart rate and decreasing the force of heart contractions, thereby improving blood flow and reducing pressure on the arteries. Before starting Nebivolol, it is crucial to consult a healthcare provider to discuss your medical history, current conditions, and allergies to ensure it is safe for you to take. It is essential to read the patient information leaflet for safety information and directions on how to use the medication. Depending on your unique needs, Nebivolol is typically taken once or twice a day; the tablets should be swallowed whole, preferably during a meal, to avoid an upset stomach. It is important to take Nebivolol regularly, as prescribed, even if you feel well, as it is used to control symptoms and manage conditions effectively.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to Nebivolol or any of the other ingredients in the medication.
    • You have severe heart failure.
    • Your heart cannot pump enough blood to your body and you have swelling or fluid build-up in your lungs.
    • You have severe blood pressure issues with excessive lowering of blood pressure.
    • You have severe liver problems or organ disease.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Edema
    • Headaches
    • Dizziness
    • Fatigue
    • Sweating
    • Constipation
    • Hypotension
    • Angina
    • Abdominal pain
    • Rash
    • Myocardial Infarction

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  • Precautions & Warnings

    Here are some important warnings and precautions to consider:

    • Patients with peripheral circulatory disorders such as Raynaud's disease or intermittent claudication should use the medication with caution, as it may exacerbate these conditions.
    • Individuals with 1st-degree heart block, Prinzmetal's angina, diabetes mellitus, or thyroid disease should be monitored closely, as the medication may impact cardiovascular function and metabolic control.
    • Those with a history of psoriasis, COPD, or severe anaphylaxis to various allergens, as well as individuals with myasthenia gravis, should use the medication carefully due to potential exacerbation of these conditions.
    • For patients undergoing surgery, avoid abrupt withdrawal of the medication. Chronic therapy should not be routinely discontinued before major surgery.
    • The medication may mask the signs and symptoms of hypoglycaemia and hyperthyroidism, particularly tachycardia.
    • It is important to note that the medication is not recommended for individuals with severe renal impairment when used for chronic heart failure.
    • Use with caution in elderly patients, and consult with a healthcare provider before use during pregnancy and lactation.

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  • Drug Interactions

    Drug interactions with nebivolol include:

    • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) (may increase nebivolol levels)
    • Other antihypertensives (e.g., calcium channel blockers) (may have additive effects on blood pressure)
    • Antiarrhythmics (e.g., amiodarone) (may increase risk of bradycardia and heart block)
    • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen) (may reduce the effectiveness of nebivolol)
    • Insulin and oral antidiabetics (e.g., metformin) (may mask hypoglycemia symptoms)

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  • Storage/Disposal

    Nebivolol is a drug used to treat high blood pressure and it should be stored at room temperature between 59°F and 86°F in a safe, secure location, away from children and pets, with the container tightly closed, away from any moisture or direct sunlight. The medication should be discarded appropriately after the expiration date and any further questions about storage should be directed to a healthcare professional.

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