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Product Information
Nalidixic acid primarily targets bacterial DNA gyrase, a type II topoisomerase essential for DNA replication, transcription, and repair in bacteria. It acts as a competitive inhibitor, binding to the enzyme's active site and preventing it from catalyzing the breaking and rejoining of DNA strands. This binding interferes with the DNA gyrase's ability to introduce negative supercoils into DNA, which is crucial for DNA supercoiling and maintaining the structural integrity of bacterial DNA. By inhibiting DNA gyrase, nalidixic acid disrupts DNA replication and transcription, leading to bacterial cell death. This mechanism is selective for bacterial cells because DNA gyrase is not present in mammalian cells, making it an effective antibiotic against susceptible bacteria.
Quinolone antibiotic
Suspension
The following are the uses of Nalidixic Acid Syrup/Suspension:
To be taken as per doctor's prescription
In the case of an overdose of Nalidixic Acid Syrup/Suspension, immediate medical attention is necessary. Symptoms may include nausea, vomiting, dizziness, and in severe cases, seizures or respiratory distress. Prompt action should be taken, such as contacting a healthcare professional or a poison control center, who can provide specific guidance based on the patient's condition and the amount ingested. Quick response and appropriate medical care are crucial to managing and minimizing the risks associated with overdosing.
In the case of a missed dose of Nalidixic Acid Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions. It is crucial to maintain a consistent dosing routine for this medication to ensure its effectiveness.
To administer Nalidixic Acid Syrup/Suspension, shake the bottle well, measure the prescribed dose with a dosing spoon or oral syringe, and take it orally, following the recommended dosage instructions provided by your healthcare professional, typically taken every 6 hours, with or without food, ensuring not to exceed the prescribed amount.
Here are the conditions or situations when Nalidixic Acid Syrup/Suspension should not be used:
The side effects of Nalidixic Acid Syrup/Suspension may include:
Following are the precautions and warnings for Nalidixic Acid Syrup/Suspension:
Following are the drug interactions for Nalidixic Acid Syrup/Suspension:
Following are the food interactions for Nalidixic Acid Syrup/Suspension:
Nalidixic Acid Syrup/Suspension requires careful storage and disposal to ensure safety and environmental responsibility. Store it at room temperature, away from sunlight and moisture, preferably in its original container with a tight-fitting lid to maintain its integrity. Avoid extreme temperatures by keeping it away from heat sources like ovens or radiators. Always check the expiration date, and if the medication is expired or no longer needed, do not flush it or pour it down the drain. Contact your pharmacist or healthcare provider for instructions on proper disposal methods. Keep the syrup securely stored, out of children's reach, to prevent accidental consumption. Responsible storage and disposal practices are crucial for the well-being of both individuals and the environment.
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Following are the quick tips for Nalidixic Acid Syrup/Suspension:
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