NeoQuel XR (300mg) 30 Tablets

Quetiapine 300mg tablets primarily exert their therapeutic effects through a combination of actions on multiple neurotransmitter receptors in the brain. It acts as an antagonist at dopamine D2 and serotonin 5-HT2A receptors, which contributes to its antipsychotic and mood-stabilizing properties. Quetiapine also displays partial agonist activity at certain serotonin (5-HT1A) and norepinephrine (α1 and α2) receptors, promoting neurotransmitter signaling in these systems. This unique receptor profile helps improve symptoms of schizophrenia, bipolar disorder, and major depressive disorder by modulating dopamine, serotonin, and norepinephrine activity, ultimately aiding in the restoration of neurotransmitter balance in the brain.

Antipsychotic medication

Tablet

The following are the uses of Quetiapine 300mg Tablet:

• Used for treating schizophrenia, helping patients manage hallucinations, delusions, and disordered thinking.
• Used for controlling symptoms of bipolar disorder, including manic and depressive episodes.
• Used for mood stabilization, particularly in bipolar disorder, to prevent extreme mood swings.
• Used for addressing severe depression when other antidepressants may not be effective.
• Used for managing severe anxiety disorders, aiding in reducing symptoms of anxiety and improving overall well-being.
• Used for assisting in sleep regulation, especially in individuals with insomnia related to mental health conditions.
• Used for helping individuals with certain behavioral disorders, such as impulse control and aggression issues.
• Used for providing relief in specific cases of chronic pain, often associated with psychological factors.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• 300 mg is a typical dosage of Quetiapine, which is often prescribed as a once-daily dosage
• Your doctor will be able to determine your required dosage, as it varies per medication and per patient depending on a number of factors. These factors include medication efficacy, tolerance for side-effects, age, weight, prescription history, etc.
• You should reach out to a medical professional directly if you have any further questions about Quetiapine, for tailored guidance.

In the case of an overdose of Quetiapine 300mg Tablets, several symptoms may occur. These can include severe drowsiness, rapid heartbeat, and even fainting. It is important to recognize the signs of an overdose, which may also lead to difficulty breathing and an irregular heartbeat. If you suspect an overdose, seek medical advice promptly as this can be a serious medical emergency. Prompt action can ensure the best possible outcome and prevent potential complications.

In the case of a missed dose of Quetiapine 300mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, it's important to discuss this with your healthcare provider to determine the best course of action and ensure the medication's effectiveness.

To take Quetiapine 300mg Tablet, swallow the tablet whole with a full glass of water, preferably at bedtime or as directed by your healthcare professional, and do not crush, chew, or split the tablet.

Here are the conditions or situations when Quetiapine 300mg Tablet should not be taken:

• Avoid use in patients with known hypersensitivity or severe reaction to quetiapine or any of its excipients.
• Do not use in patients with known risk of angle-closure glaucoma.
• Contraindicated in patients with a history of bone marrow suppression or a current low white blood cell count.
• Should not be used in patients with liver disease or impaired liver function.
• Avoid use in individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Not recommended for elderly patients with dementia, as it may increase the risk of death.
• Do not use in patients with uncontrolled high or low blood pressure.
• Contraindicated during breastfeeding, as it may pass into breast milk and harm the nursing infant.

The side effects of Quetiapine 300mg Tablet may include:

• Drowsiness or sedation
• Dizziness
• Dry mouth
• Increased appetite and weight gain
• Fatigue or feeling tired
• Blurred vision
• Constipation
• Restlessness or agitation

Following are the precautions and warnings for Quetiapine 300mg Tablet:

• This medication may cause drowsiness and dizziness, so patients should not drive or operate heavy machinery until they know how it affects them.
• Elderly patients should be closely monitored, as they may be more sensitive to the side effects of this medication.
• Quetiapine can cause weight gain, so regular monitoring of weight and other metabolic parameters is recommended.
• Blood tests may be required to monitor liver function, blood sugar levels, and cholesterol levels while on this medication.
• Patients with a history of seizures or epilepsy should be cautious, as Quetiapine may lower the seizure threshold.
• Not recommended for patients with certain medical conditions such as liver disease, heart problems, or low white blood cell count.
• Pregnant and breastfeeding women should consult their doctor as the risks and benefits should be carefully considered before prescribing this medication.

Following are the drug interactions for Quetiapine 300mg Tablet:

• Quetiapine may enhance the effects of CNS depressants like opioids, benzodiazepines, and alcohol, leading to increased sedation and respiratory depression.
• It can interact with medications metabolized by CYP3A4 enzymes, such as ketoconazole, potentially increasing quetiapine levels.
• Use with other antipsychotics or certain antidepressants may elevate the risk of side effects like extrapyramidal symptoms and serotonin syndrome.
• Quetiapine may increase the effects of certain antihypertensive medications, leading to orthostatic hypotension.
• Blood sugar levels may be affected when used with antidiabetic medications, requiring monitoring.
• Anticonvulsant medications like phenytoin and carbamazepine can decrease quetiapine levels, potentially reducing its effectiveness.
• Caution is advised with lithium, as quetiapine may increase lithium levels, requiring close monitoring.

Following are the food interactions for Quetiapine 300mg Tablet:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Quetiapine, potentially leading to increased drug levels in the blood and an elevated risk of side effects.
• Alcohol consumption should be minimized or avoided as it can enhance the sedative effects of Quetiapine, causing excessive drowsiness and impaired coordination.
• Fatty meals can slightly decrease the absorption of Quetiapine, but this interaction is not considered clinically significant.
• Avoid caffeine-rich foods and beverages as they may counteract the sedative effects of Quetiapine, potentially reducing its effectiveness in treating insomnia.
• Consuming Quetiapine with a light meal can help reduce the risk of dizziness and lightheadedness, especially during the initial days of treatment.
• Maintain a consistent intake of potassium-rich foods like bananas, oranges, and spinach, as Quetiapine may occasionally cause low potassium levels.
• Avoid excessive salt intake, especially in individuals with hypertension, as Quetiapine may lead to water retention and increased blood pressure in some cases.
• Stay well-hydrated by drinking plenty of fluids to minimize the risk of dehydration, particularly in hot weather or during intense physical activity.

Quetiapine 300mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (68°F to 77°F or 20°C to 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air and humidity. When disposing of unused or expired tablets, do not throw them in the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal, which may involve returning them to a pharmacy or a designated collection point to ensure safe and environmentally friendly disposal. Keep the medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Quetiapine 300mg Tablet:

• Take the tablet as directed by your doctor, typically once daily.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Maintain a consistent daily routine for taking the medication.
• Avoid alcohol consumption while on this medication.
• Do not stop taking the medication without consulting your doctor.
• If you experience dizziness, rise slowly from a sitting or lying position.
• Store the tablets in a cool, dry place, away from direct sunlight.

Quetiapine is a medication that can cause chemical changes in the body, so lab tests are needed to monitor any adverse effects and ensure safe usage. While taking Quetiapine, your doctor will typically require specific lab tests and assessments to evaluate your health status, including: