Neopres (5mg) 20 Tablets

Amlodipine 5mg tablets primarily work by blocking calcium channels in the cardiovascular system, specifically targeting L-type calcium channels in vascular smooth muscle cells. This mechanism of action leads to the relaxation and dilation of blood vessels, which in turn lowers blood pressure. By inhibiting the movement of calcium ions into these cells, amlodipine reduces the force of contraction in the vascular smooth muscle, resulting in decreased peripheral vascular resistance and improved blood flow. This vasodilation effect is particularly beneficial in treating hypertension, as it helps to reduce the workload on the heart and enhance blood circulation throughout the body.

Amlodipine 5mg

Calcium channel blocker

Tablet

The following are the uses of Amlodipine 5mg Tablet:

• Used for treating high blood pressure, helping control and manage hypertension.
• Used for relieving angina, reducing chest pain and associated symptoms.
• Used for preventing myocardial infarction, lowering the risk of heart attacks.
• Used for managing coronary artery disease, improving blood flow to the heart.
• Used for treating Raynaud's phenomenon, alleviating symptoms in affected areas.
• Used for controlling blood pressure in diabetes patients with hypertension.
• Used for improving exercise tolerance, enabling better physical activity.
• Used for long-term management of cardiovascular health, supporting overall well-being.

In the case of an overdose of Amlodipine 5mg Tablets, it is important to recognize the potential symptoms and act swiftly. Overdose may lead to an excessive drop in blood pressure, causing dizziness, lightheadedness, and fainting. Other signs include rapid or weak pulse, nausea, and fatigue. Immediate action is necessary; contact a healthcare professional or seek emergency medical assistance promptly to ensure appropriate treatment and prevent potential complications.

In the case of a missed dose of Amlodipine 5mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss several doses, contact your healthcare provider for advice, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses. It is generally best to take the missed dose as soon as possible to maintain consistent medication levels in your body.

To take Amlodipine 5mg Tablets, swallow one tablet daily with a glass of water, preferably at the same time each day, as directed by your healthcare provider, and do not crush, chew, or break the tablet.

Following are the conditions/situations when Amlodipine 5mg Tablet should not be used:

• Should not be used in patients with a known allergy to Amlodipine or other calcium channel blockers.
• Contraindicated in patients with severe hypotension (very low blood pressure).
• Should not be used in patients with acute myocardial infarction (heart attack).
• Not recommended for individuals with aortic valve stenosis (narrowing of the aortic valve in the heart).
• Avoid use in patients with unstable angina (chest pain) or severe coronary artery disease.
• Contraindicated in patients with cardiogenic shock (shock caused by heart dysfunction).
• Should not be used in patients with obstructive jaundice (liver condition with blocked bile flow).
• Not suitable for individuals with severe liver impairment.

The side effects of Amlodipine 5mg Tablet may include:

• Swelling of the ankles and feet (peripheral edema)
• Dizziness or lightheadedness
• Fatigue and weakness
• Headache
• Stomach pain or discomfort
• Flushing (feeling of warmth or redness in the face)
• Palpitations (feeling of a rapid or pounding heartbeat)
• Muscle cramps

Following are the precautions and warnings for Amlodipine 5mg Tablet:

• Do not abruptly discontinue the medication, as it may lead to worsening of angina or hypertension. Gradual reduction is recommended under medical supervision.
• Elderly patients may be more sensitive to the effects and should start with a lower dose.
• Caution is advised in patients with liver problems, as the medication is metabolized by the liver. Regular monitoring is necessary.
• Amlodipine can cause swelling of gums, so maintain good oral hygiene and dental care during treatment.
• Patients with heart failure should be closely monitored, as the medication may worsen symptoms in rare cases.
• Diabetic patients should be aware that amlodipine may affect blood sugar levels. Monitor blood glucose regularly.
• Inform your doctor if you have any heart or blood vessel diseases before taking this medication.

Following are the drug interactions for Amlodipine 5mg Tablet:

• Diltiazem and verapamil (calcium channel blockers) can increase the blood levels of amlodipine, leading to enhanced effects and potential side effects.
• Grapefruit juice can inhibit the metabolism of amlodipine, resulting in increased drug levels and possible adverse reactions.
• Rifampicin (an antibiotic) may decrease the effectiveness of amlodipine by inducing its metabolism.
• Amlodipine can enhance the blood pressure-lowering effects of antihypertensive medications, including beta-blockers and ACE inhibitors.
• The combination with digoxin (a heart medication) may increase digoxin levels, requiring monitoring and dose adjustments.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) might reduce the antihypertensive effects of amlodipine.
• Certain antifungal medications (e.g., ketoconazole) can increase amlodipine levels, requiring careful monitoring.

Following are the food interactions for Amlodipine 5mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they can increase the levels of Amlodipine in the blood, potentially leading to increased side effects.
• Avoid excessive alcohol consumption as it may lower blood pressure further and increase the risk of dizziness and lightheadedness.
• Avoid high-sodium foods as Amlodipine is used to treat high blood pressure, and a high-sodium diet can counteract the medication's effectiveness.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed moderately as Amlodipine can sometimes cause an increase in potassium levels.
• Licorice, a natural sweetener, should be avoided as it may decrease the effectiveness of Amlodipine by reducing its absorption.
• Avoid consuming large amounts of high-fat meals as they may delay the absorption of Amlodipine, affecting its effectiveness.
• Always ensure a consistent intake of fluids to maintain hydration, especially if experiencing side effects like swelling.

Amlodipine 5mg Tablets should be stored in a secure and dry location, preferably at room temperature, ensuring protection from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. When disposing of unused or expired tablets, do not flush them down the toilet or pour them into any drainage system. Instead, seek guidance from a pharmacist or healthcare professional on the appropriate disposal methods to minimize environmental impact. Additionally, exercise caution to keep the medication out of children's reach to prevent accidental ingestion, ensuring their safety. Regularly checking the expiration date on the packaging before using the medication is a vital practice to ensure its effectiveness.

Following are the quick tips for Amlodipine 5mg Tablet:

• Take the tablet at the same time each day to maintain consistent blood levels.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Amlodipine can be taken with or without food, but taking it with food may reduce side effects.
• Do not stop taking the medication without consulting your doctor, even if you feel better.
• Avoid grapefruit and grapefruit juice as they can affect the medication's effectiveness.
• Inform your doctor about all medications you are taking to prevent potential interactions.
• Store the tablets at room temperature, away from moisture and direct sunlight.