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Neotret (25mg) 30 Capsules

Neotret (25mg) 30 Capsules

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  • Manufacturer Pharma Health Pakistan (Pvt.) Ltd.
  • Generic Name Acitretin
Rs. 768.66 Rs. 904.3
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Product Information

  • Description

    Acitretin is a synthetic derivative of etretinate, a second-generation retinoid used for treating psoriasis. It acts by reducing the production of new skin cells, slowing keratinocyte proliferation and it exerts anti-inflammatory actions, reducing neutrophil migration and inhibiting inflammatory cytokine activity. Acitretin downregulates the expression of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-8, within involved immune cells and it is believed to inhibit cell growth and inflammation, alleviating psoriasis symptoms.

  • Ingredients

  • Drug Class


  • Dosage Form

  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Acitretin 25mg is effective in treating psoriasis, a skin condition characterized by rapid growth of skin cells and inflammation.
    • Acitretin 25mg is used to treat other skin conditions like acne, ichthyosis, and keratinization disorders.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For acute pityriasis lichenoides, a dosage of 25mg daily for a period of 4-6 months is typically recommended.
    • For psoriasis, Acitretin is usually dosed at 0.5-1mg/kg/day, and it's recommended to start at a lower dose of 25mg daily and increase gradually every week or every other week by 25mg or 37.5mg depending on the response and tolerance to the drug.
    • For severe psoriasis unresponsive to milder therapies, Acitretin can be prescribed at a dose of 50mg daily.
    • Acitretin is associated with increased risk of birth defects, therefore, it is important to avoid pregnancy while taking this drug, and for at least 3 years after stopping Acitretin.
    • It is important to follow the dosing instructions provided by your physician specifically tailored to you.
    • If you are experiencing any side effects, discomfort, or unexpected symptoms, notify your physician immediately.
  • In case of Overdose

    Acitretin is a prescription medication that is given to patients suffering from skin disorders like psoriasis. It is beneficial for such conditions but also has the potential to cause severe side effects and drug interactions. There is an elevated risk of specific cancers associated with Acitretin use as well. Suppose a person experiences an Acitretin overdose. In that case, it is essential to seek immediate medical advice from a qualified healthcare provider for proper guidance and treatment

  • Missed Dose

    It is crucial to notify your healthcare provider immediately if you have missed a dose of acitretin 25mg. You could take the missed dose as soon as possible, unless it's nearly time for your next scheduled dose. In this case, you should skip the missed dose and resume your regular dose schedule. It is not recommended to take extra doses or double up to make up for a missed dose, as this may increase the risk of side effects.To ensure the best possible results and reduce the risk of complications, it is essential to adhere to the dosing schedule provided by your healthcare provider. If you miss a dose, you should consult with your healthcare provider or pharmacist to understand specific instructions pertaining to the missed dose and general guidelines for moving forward. Any further questions or concerns should be addressed by your healthcare provider or pharmacist, as they may provide you with the most suitable advice based on your health condition and treatment plan.

  • How To Use

    Before taking Acitretin 25mg, it is important to discuss your medical history and allergies with your doctor to ensure that the medication is safe for you to take. This medication treats skin conditions like psoriasis and acne and can cause severe birth defects, so contraception is necessary for women of child-bearing age. Your doctor will likely conduct routine blood tests to monitor any changes during treatment. Follow your doctor's exact dosage instructions and remember not to exceed the recommended dosage, as this can lead to severe side effects. Mild side effects include skin irritation, itching, dryness, and redness, while more severe side effects can include mood changes, vomiting, and peeling skin. It is important to inform your doctor about all other substances you are taking, including vitamins and other medications, to avoid interactions. Finally, it is important to attend all follow-up appointments once you have completed the course of Acitretin 25mg, so your doctor can ensure that the treatment has successfully managed your condition and make any necessary adjustments.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Women who are pregnant or who want to become pregnant should not take Acitretin, as it can cause severe birth defects.
    • People with a history of mental health issues, especially depression, should avoid this medication because it can cause mood swings or make depression worse.
    • Patients should avoid taking Acitretin if they have recently had or are scheduled to have COVID vaccinations within the next month, as it may render the vaccination ineffective and place the patient at risk.
    • Those with a history of liver problems should not take Acitretin, as the medication can place additional stress on the liver.
    • People with known sensitivities or allergic reactions to Acitretin or any of its ingredients should not take this medication, as allergic reactions must be reported to medical staff.
    • Patients with a history of cancer should avoid Acitretin, as it can cause certain types of cancer to develop or spread.
    • Acitretin should not be taken by those who are taking other medications, especially immunosuppressants or antivirals, as there is risk of harmful interactions.
    • It is essential to consult a medical professional for personalized guidance before taking Acitretin to ensure it is appropriate and safe for you.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Increases appetite
    • Promotes weight gain
    • May cause headaches
    • Can increase cholesterol levels
    • Tendency to develop acne
    • Dry eyes
    • Dry skin
    • Increased thirst
    • Urgency to urinate
  • Storage/Disposal

    Acitretin is a medication that requires careful storage to preserve its effectiveness and ensure its safety. The optimal storage conditions for Acitretin 25mg are in a secure location, accessible only to those for whom it is prescribed. This medication should be stored at a controlled room temperature between 20°C and 24°C (68°F and 75°F). For safekeeping, ensure it is out of reach of children, pets, and any other unintended users. The container should remain airtight with its cap or lid firmly closed after each use to prevent moisture from infiltrating the medication. The container should also be stored in a cool, dry place, away from direct sunlight and heat. Bathrooms or areas near sinks are not ideal for this purpose, as high humidity and abrupt temperature changes can impede drug integrity. Should you need to dispose of any unused Acitretin 25mg pills, it is imperative to do so safely and in accordance with the guidance provided by your physician or local regulations. Never share your medication with others, as doing so may compromise the effectiveness of the prescription and derail the intended recovery or treatment process. It is worth noting that Acitretin's efficacy and safety are optimized by adhering to the precise storage guidelines. If you have any specific queries or concerns regarding the storage of Acitretin 25mg, do not hesitate to consult your pharmacist or healthcare provider.

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