Nexum (20mg) 28 Tablets

Nexum (20mg) 28 Tablets

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  • Manufacturer AstraZeneca
  • Generic Name

    Esomeprazole 20mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Esomeprazole is a proton pump inhibitor (PPI) orally administered to manage symptoms associated with stomach acid disorders, including gastroesophageal reflux disease (GERD) and ulcers. Unlike other PPIs, esomeprazole is designed with a delayed release capsule, harnessing the medication's full effects by protecting its active ingredient from stomach acid. This intelligent design allows for optimal absorption, ensuring the medication works effectively. It is typically recommended to take esomeprazole once daily, usually at mealtimes, as directed by a healthcare professional. The particular dosage, 20mg, was devised to accommodate more severe cases of GERD or ulcers requiring robust acid suppression. Notably, prolonged use of PPIs, in general, may correlate with diminished calcium absorption, increased risk of bone fractures, and certain bacterial infections. It is crucial to highlight that PPIs should be used sparingly and only for the shortest time possible. To ensure the safest and most effective use of esomeprazole, consult your healthcare provider for personalized guidance.

  • Ingredients

    Esomeprazole 20mg

  • Drug Class

    Proton Pump Inhibitors (Ppis)

  • Dosage Form

    Tablet

  • Uses

    Esomeprazole is utilized for the following therapeutic indications:

    • Treatment of gastroesophageal reflux disease (GERD)
    • Management of peptic ulcer disease
    • Prevention of NSAID-induced gastric ulcers
    • Support for Zollinger-Ellison syndrome
    • Treatment of erosive esophagitis
    • Reduction of heartburn and acid regurgitation symptoms
    • Long-term maintenance of healed esophagitis
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Heartburn and Gastroesophageal Reflux Disease (GERD)- Esomeprazole 20 mg is prescribed for short-term treatment of heartburn and GERD. Dose is 20 mg once daily for 4 weeks.
    • Ulcer Prevention- Esomeprazole 20 mg is prescribed to prevent ulcers associated with taking painkillers. Dose is 20 mg once daily for up to 4 months.
    • Ulcer Healing- Esomeprazole 20 mg is prescribed to promote ulcer healing. Dose is 40 mg once daily for 4 weeks.
    • Zollinger-Ellison Syndrome- Esomeprazole 20 mg is used to treat Zollinger-Ellison syndrome, a condition characterized by excessive stomach acid production. Dose is typically higher, ranging between 60-120 mg once daily, adjusted individually and combined with other medications.
  • In case of Overdose

    Esomeprazole is a medication that is generally considered safe, with a wide margin of safety, meaning therapeutic doses are well-tolerated, and accidental overdoses are rarely dangerous. In rare cases of an overdose, it can still lead to unpleasant symptoms such as nausea, vomiting, and diarrhea. More severely, it may also cause tremors, confusion, difficulty breathing, and loss of consciousness.In terms of treatment, it involves inducing vomiting and administering charcoal to absorb the drug remaining in the stomach. Giving frequent doses of an antacid like sodium bicarbonate can help reduce drug absorption. It is essential to note that gastric lavage may be considered if the patient presents within an hour of ingestion to try and remove the drug from the stomach. Monitoring for any signs of arrhythmia and pepsin secretion is necessary to watch for any potential complications. In cases of long-term usage at higher doses, gradually tapering the dosage can help to minimize the withdrawal symptoms of the drug, which may include symptoms such as nausea, vomiting, and diarrhea. Overall, Esomeprazole is considered safe and effective in treating stomach acid-related disorders, and its mild toxicity can be safely managed in most cases.

  • Missed Dose

    If you miss a dose of Esomeprazole, it is important to take it as soon as possible unless it is close to your regular dosing time. In that case, you should skip the missed dose and continue on your regular schedule. It is not recommended to double up on doses. If you have any questions or concerns, be sure to consult your doctor. It is crucial to take Esomeprazole as prescribed by your doctor, as it is intended to be taken regularly to be effective. Missing doses can reduce its effectiveness and impact your treatment plan.

  • How To Use

    Before starting your course of Esomeprazole (20mg), it's important to read the medication guide provided by your pharmacist. This guide will provide you with important information on how and when to take your medication, potential side effects, and precautions you should take. If you have any questions, make sure to ask your doctor or pharmacist. Esomeprazole is usually taken once or twice a day, at least 1 hour before a meal. It's important to take it regularly as prescribed by your doctor. Swallow the capsule whole, but if you have difficulty swallowing, you may open the capsule and sprinkle its contents on a small amount of soft food, liquid, or a medication dose calculator. Take the mixture right away, without chewing or crushing the drug. The dosage of Esomeprazole is based on your medical condition and how you respond to the treatment. Do not take more or less of it, or take it more often than prescribed. If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. It's important to take Esomeprazole regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Even if you feel well, continue to take it as directed. Stopping the medication suddenly may result in your condition worsening or returning

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to Esomeprazole or any of its ingredients.
    • You have experienced significant liver disease or an organic cause of acidosis such as kidney failure.
    • You are taking a prescription that interacts negatively with Esomeprazole, including warfarin and anti-coagulants (blood thinners), or methotrexate (used for certain cancers or rheumatoid arthritis).
    • You are pregnant or plan to become pregnant.
    • You are breastfeeding.
    • You have experienced a recent severe hypersensitivity reaction (e.g., angioedema, urticaria, difficulty swallowing or breathing).
    • You have any concerns about taking Esomeprazole.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Headaches
    • Nausea
    • Diarrhea
    • Constipation
    • Dry mouth or eyes
    • Itchiness
    • Increased thirst
    • Bloody stool
    • Taste alterations
    • Stomach pain
    • Rash
    • Weakness
    • Muscle pain
    • Severe joint pain
    • Memory problems
    • Confusion
  • Storage/Disposal

    Esomeprazole should be kept in a cool, dry place, away from heat, light, and moisture. It is best to store the medication at room temperature, approximately 25°C (77°F). It is not recommended to store Esomeprazole in the bathroom or any area with high humidity, as this may affect the drug's potency. Furthermore, it is important to keep this medication out of the reach of children and to avoid sharing the medication with others, even if they have the same condition.

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