Nicoget (20mg) 20 Tablets

Niacin (nicotinic acid) is a B-complex vitamin that plays a role in energy metabolism in the body. Nicronadil 20mg Tablet contains niacin in an extended-release form. The mechanism of action of niacin in this context is primarily related to its ability to reduce levels of triglycerides and low-density lipoprotein (LDL) cholesterol, while increasing high-density lipoprotein (HDL) cholesterol. Niacin achieves this by inhibiting the action of an enzyme called hepatic lipase, which breaks down HDL cholesterol, leading to increased levels of HDL. It also suppresses the production of very-low-density lipoprotein (VLDL), which is eventually converted to LDL cholesterol, thereby reducing LDL levels. Additionally, niacin stimulates the removal of triglycerides from the blood by activating lipoprotein lipase, an enzyme that breaks down triglycerides.

Nitrate vasodilator.

Tablet

The following are the uses of Nicronadil 20mg Tablet:

• Used for managing hypertension, effectively lowering high blood pressure.
• Used for treating angina, providing relief from chest pain.
• Used to prevent and manage heart-related chest pain during physical activities.
• Used for improving exercise tolerance in individuals with cardiovascular issues.
• Used to enhance blood flow and reduce the workload on the heart.
• Used in the long-term management of cardiovascular conditions.
• Used to support a healthy heart and cardiovascular system.

In the case of an overdose of Nicronadil 20mg Tablets, it is important to recognize the signs and act swiftly. Common symptoms may include severe dizziness, fainting, a rapid or irregular heartbeat, and difficulty breathing. If you suspect an overdose, contact a healthcare professional or poison control center immediately. Quick action can prevent potential complications and ensure the best possible outcome. It is crucial to keep this medication out of reach of children to prevent accidental ingestion.

In the case of a missed dose of Nicronadil 20mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking a family member to help you remember to take your medication on time. It is crucial to maintain consistency with your medication regimen for optimal effectiveness.

To take Nicronadil 20mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically once daily.

Nicronadil 20mg Tablet should not be used in the following conditions:

• If you have a known allergy to Nicronadil or any of its components, do not take this medication.
• This medication is contraindicated in patients with severe liver impairment or active liver disease.
• Avoid using Nicronadil if you have a history of angioedema (swelling of the face, lips, tongue, or throat) after taking similar medications.
• Do not take this tablet if you have a rare hereditary problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• It is not recommended for individuals with a history of heart rhythm problems (cardiac arrhythmias) or severe heart failure.
• Nicronadil is not suitable for patients with unstable angemic (chest pain) or a recent heart attack.
• Do not use this medication if you have low blood pressure (hypotension) or uncontrolled hypertension (high blood pressure).

The side effects of Nicronadil 20mg Tablet may include:

• Flushing (warmth, redness, or tingling under the skin)
• Headache
• Dizziness
• Nausea
• Stomach pain
• Diarrhea
• Fatigue
• Increased heart rate

Following are the precautions and warnings for Nicronadil 20mg Tablet:

• Not recommended for individuals with known hypersensitivity or allergy to nicronadil or any other ingredients in the tablet.
• Patients with a history of liver disease should exercise caution and seek medical advice before taking this medication, as it may affect liver function.
• Nicronadil may cause dizziness or lightheadedness; patients should avoid driving, operating heavy machinery, or performing tasks that require alertness until they know how the medication affects them.
• Elderly patients may be more susceptible to side effects; dosage adjustments might be necessary for this population.
• This medication should be used with caution in patients with cardiovascular diseases, as it can impact blood pressure and heart rate.
• Patients with a history of gastrointestinal disorders should be monitored for any gastrointestinal side effects while on this medication.
• Nicronadil may interact with other medications; inform your doctor about all medications you are currently taking to prevent potential drug interactions.
• Seek immediate medical attention if you experience any severe or unusual symptoms while taking this medication.

Following are the drug interactions for Naphazoline drop:

• Concomitant use with monoamine oxidase inhibitors (MAOIs), such as phenelzine, can cause a hypertensive crisis due to an increase in norepinephrine levels.
• Beta-blockers, such as propranolol, may enhance the hypertensive effect of naphazoline, increasing the risk of elevated blood pressure.
• Tricyclic antidepressants (TCAs), like amitriptyline, can increase the risk of cardiovascular side effects, such as hypertension or tachycardia, when used with naphazoline.
• Other sympathomimetic drugs, including decongestants or stimulant medications, may lead to excessive vasoconstriction, increasing the risk of adverse cardiovascular effects.
• Corticosteroids when used locally or systemically may enhance the potential for side effects like ocular hypertension when combined with naphazoline.
• Antihypertensive drugs may have reduced efficacy when used with naphazoline, as it may counteract the blood pressure-lowering effects of these medications.

Following are the food interactions to be aware of when taking Nicronadil 20mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Nicronadil in the blood, potentially leading to an increased risk of side effects.
• Alcohol intake should be minimized or avoided as it may exacerbate the side effects of Nicronadil, including dizziness and lightheadedness.
• Caffeine-rich beverages like coffee and energy drinks might interact with Nicronadil, intensifying its impact on blood pressure and heart rate.
• Foods high in salt or sodium can counteract the effects of Nicronadil, which is often prescribed to manage blood pressure, potentially reducing its effectiveness.
• Consuming potassium-rich foods like bananas, oranges, and spinach is advisable as Nicronadil may lower potassium levels in the body.
• Nicronadil may interact with certain herbal supplements, so it's important to inform your healthcare provider about any herbal remedies you are taking.
• There is no specific dietary restriction with Nicronadil, but maintaining a balanced diet is generally recommended for overall health.
• Always follow the advice of your healthcare provider regarding dietary considerations while taking Nicronadil.

Nicronadil 20mg Tablets should be stored in a cool, dry area, preferably in their original container, away from direct sunlight and moisture. It is crucial to maintain a controlled room temperature for optimal storage conditions. Always keep the medication sealed tightly to maintain its integrity and prevent contamination. When disposing of Nicronadil tablets, do not flush them down the toilet or discard them into drains. Instead, consult your local pharmacist or healthcare provider for specific guidelines on proper disposal methods in your area. Ensure that the medication is kept out of children's reach to prevent accidental consumption. Regularly check the expiration date, and discard any unused or expired tablets according to the recommended procedures.

Following are the quick tips for Nicronadil 20mg Tablet:

• Consult your doctor before starting this medication and provide your complete medical history.
• Take the tablet as directed by your doctor, typically once daily.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Take it at the same time each day to maintain consistent blood levels.
• Do not stop taking the medication without consulting your doctor, even if you feel better.
• Inform your doctor about all other medications you are taking to prevent potential drug interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.