NIMOBID 100MG TAB

Nimodipine, a 100MG dosage strength in tablet form, acts as a calcium channel blocker, primarily targeting L-type calcium channels in the brain. Its mechanism of action involves selectively inhibiting the influx of calcium ions into smooth muscle cells and neurons. By blocking these channels, nimodipine reduces the intracellular calcium levels, leading to smooth muscle relaxation, particularly in cerebral blood vessels. This vasodilation effect helps improve blood flow in the brain, thereby preventing or treating conditions associated with reduced cerebral blood flow, such as cerebral vasospasm. The drug's specific action on cerebral blood vessels is attributed to its ability to cross the blood-brain barrier and exert its effects directly on the vascular smooth muscle cells in the brain.

Calcium channel blocker.

Tablet

The following are the uses of Nimodipine 100MG Tablet:

• Used for treating bleeding in the brain due to ruptured aneurysms.
• Used to improve neurological outcomes and reduce the risk of long-term disability.
• Used to relax and widen blood vessels, improving blood flow to the brain.
• Used for managing subarachnoid hemorrhage complications and preventing vasospasm.
• Used to alleviate headaches and promote overall recovery in patients.
• Used to support intensive care management and prevent further brain damage.
• Used for short-term treatment, typically for 21 days, under medical supervision.
• Used to provide a targeted approach to treating cerebral vasospasm.

In the case of an overdose of Nimodipine 100MG Tablets, individuals may experience severe side effects such as a significant drop in blood pressure, leading to dizziness, lightheadedness, and fainting. Other symptoms could include an irregular heartbeat, extreme drowsiness, and even seizures. It is important to seek medical assistance promptly if an overdose is suspected, as these symptoms can be life-threatening and may require emergency treatment to stabilize the patient's condition. Timely intervention is crucial to prevent potential complications.

In the case of a missed dose of Nimodipine 100MG Tablet, it is important to take action promptly. If you remember within a few hours of the missed dose, take the missed dose as soon as possible. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your doctor or pharmacist if you are unsure about how to handle a missed dose, especially if you have missed multiple doses.

To take Nimodipine 100MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken every 4 hours or as directed by your doctor.

Following are the conditions when Nimodipine 100MG Tablet should not be taken:

• Should not be used in individuals with a known allergy or hypersensitivity to Nimodipine or other calcium channel blockers.
• Contraindicated in patients with severe hypotension (very low blood pressure).
• Not recommended for individuals with aortic stenosis (narrowing of the aortic valve in the heart).
• Should not be used in patients with unstable angina (chest pain) or within one month of a heart attack.
• Contraindicated in individuals with severe liver disease or impaired liver function.
• Not suitable for patients with cerebral hemorrhage (bleeding in the brain) due to aneurysm or head trauma.
• Should not be used in patients with severe renal impairment or those undergoing hemodialysis.
• Contraindicated during breastfeeding, as it may pass into breast milk and harm the nursing infant.

The side effects of Nimodipine 100MG Tablet may include:

• Dizziness or lightheadedness
• Headache
• Nausea and vomiting
• Flushing (warmth or redness in the face)
• Constipation or diarrhea
• Fatigue or weakness
• Peripheral edema (swelling in the legs or ankles)
• Palpitations or rapid heartbeat

Following are the precautions and warnings for Nimodipine 100MG Tablet:

• Patients with liver disease or those taking medications that affect the liver should exercise caution as Nimodipine is metabolized by the liver.
• This medication can cause a drop in blood pressure, so patients with low blood pressure should be monitored closely.
• Elderly patients may be more sensitive to the side effects, particularly dizziness and lightheadedness.
• Nimodipine may interact with other medications, especially those that affect the cardiovascular system, so a doctor should be consulted before starting any new medication.
• Patients should not stop taking the medication abruptly without medical supervision, as it may lead to a rebound increase in blood pressure.
• Pregnant and breastfeeding women should consult their doctor, as the risks and benefits of Nimodipine during pregnancy and breastfeeding are not fully established.
• Patients should avoid grapefruit and grapefruit juice during treatment, as it can affect the metabolism of Nimodipine.

Following are the drug interactions for Nimodipine 100MG Tablet:

• Nimodipine may interact with other calcium channel blockers, leading to increased hypotensive effects and potential cardiovascular risks.
• Concomitant use with beta-blockers can enhance the impact on heart rate and blood pressure.
• Antihypertensive medications, when combined with Nimodipine, may result in excessive blood pressure reduction.
• The metabolism of Nimodipine can be affected by CYP3A4 inhibitors, potentially raising its plasma levels.
• CYP3A4 inducers may decrease Nimodipine's effectiveness by reducing its plasma concentrations.
• Combining Nimodipine with diuretics may increase the risk of hypotension and electrolyte imbalances.
• Care should be taken when using Nimodipine alongside drugs affecting platelet function, as it may influence bleeding risk.

Following are the food interactions for Nimodipine 100MG Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase blood levels of Nimodipine, potentially leading to an increased risk of side effects due to CYP3A4 enzyme inhibition.
• Alcohol intake is not recommended with Nimodipine as it may exacerbate side effects like dizziness and drowsiness, and may also impact the effectiveness of the medication.
• Avoid high-fat meals as they can decrease the absorption of Nimodipine, affecting its overall effectiveness.
• Caffeine-rich foods and beverages should be limited as they may interact with Nimodipine, potentially causing increased side effects.
• Consuming foods high in potassium, like bananas and oranges, should be monitored as Nimodipine can increase potassium levels in the blood.
• Avoid natural licorice as it may lower blood pressure, which could be additive to the effect of Nimodipine, leading to hypotension.
• Always follow healthcare provider's instructions regarding dietary restrictions or recommendations during Nimodipine therapy.
• Inform your doctor about all the foods and supplements you are consuming to ensure a safe and effective treatment plan.

Nimodipine 100MG Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be used to keep the tablets and should be tightly sealed to maintain their integrity. Avoid storing near heat-emitting appliances or in bathrooms to prevent exposure to temperature fluctuations. Proper disposal of this medication is crucial; do not flush or pour it down the drain. Consult your pharmacist for safe disposal methods to protect the environment. Keep the medication out of children's reach to prevent accidental consumption, and always ensure the medication is not past its expiration date before use.

Following are the quick tips for Nimodipine 100MG Tablet:

• Consult your doctor before taking this medication, especially if you have liver or kidney issues.
• Take the tablet as directed by your doctor, usually 3-4 times daily at evenly spaced intervals.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Avoid grapefruit juice and alcohol during treatment as they may affect the medicine's effectiveness.
• Do not drive or operate machinery until you know how this medicine affects you; it may cause dizziness.
• Inform your doctor about all medications you're taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and heat.