Nitrix 2.0 (12mg) 180 Tablets

The mechanism of action of Concentrated Nitric Oxide (CNO) 12mg tablets is primarily attributed to the release of nitric oxide (NO) in the body. When CNO is administered, it undergoes a chemical reaction, leading to the generation of nitric oxide molecules. NO is a potent vasodilator, meaning it relaxes and widens blood vessels by promoting the dilation of smooth muscle cells within the vessel walls. This vasodilation reduces vascular resistance, allowing for increased blood flow and improved circulation. Additionally, nitric oxide has various physiological effects, including inhibiting platelet aggregation, reducing inflammation, and modulating cellular signaling pathways involved in angiogenesis and tissue repair. The therapeutic benefits of CNO are primarily derived from its ability to enhance blood flow and exert protective effects on the cardiovascular system through these mechanisms.

Nitric oxide donor

Tablet

The following are the uses of Concentrated Nitric Oxide 12mg Tablet:

• Used for treating and preventing conditions related to insufficient blood flow to the heart, like Angina.
• Used for managing acute heart failure, helping to improve oxygen levels and blood circulation.
• Used for addressing high blood pressure in the lungs (pulmonary hypertension).
• Used for treating respiratory distress syndrome in newborns, aiding in oxygen delivery.
• Used for managing conditions where blood vessels constrict, causing low oxygen levels.
• Used for addressing issues related to high blood pressure in the arteries.
• Used for supporting oxygen therapy in various medical scenarios.

In the case of an overdose of Concentrated Nitric Oxide 12mg Tablets, individuals may experience severe side effects. Symptoms can include intense headaches, dizziness, and difficulty breathing. Gastrointestinal issues such as nausea, vomiting, and abdominal pain might occur. It is imperative to seek medical assistance promptly. Treatment for overdose may involve supportive care, monitoring vital signs, and administering appropriate interventions to alleviate symptoms and ensure the patient's well-being.

In the case of a missed dose of Concentrated Nitric Oxide 12mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the full therapeutic benefit of the medication.

To take the Concentrated Nitric Oxide 12mg Tablet, place the tablet under your tongue and allow it to dissolve completely, preferably without swallowing for the best absorption.

Here are the conditions and situations when Concentrated Nitric Oxide 12mg Tablets should not be taken:

• Not recommended for individuals with a known sensitivity or allergy to nitric oxide or any of the tablet's components.
• Should not be used in patients with severe respiratory distress syndrome (ARDS) as it may worsen oxygenation.
• Contraindicated in individuals with methemoglobinemia or conditions that increase the risk of methemoglobinemia.
• Not suitable for patients with severe hypotension or unstable cardiovascular status.
• Avoid use in individuals with severe anemia or conditions where increased oxygen demand is not well tolerated.
• Should not be administered to patients with pulmonary hypertension or right ventricular dysfunction.
• Not recommended for individuals with a history of recent stroke or cerebral hemorrhage.

The side effects of Concentrated Nitric Oxide 12mg Tablet may include:

• Dizziness
• Headache
• Nausea and vomiting
• Dry mouth
• Fatigue and weakness
• Skin irritation or redness at the application site
• Nasal irritation or nosebleeds

Following are the precautions and warnings for Concentrated Nitric Oxide 12mg Tablets:

• Not recommended for individuals with a known sensitivity or allergy to nitric oxide or any of the tablet's components.
• Patients with a history of respiratory issues should use with caution, as it may cause respiratory distress.
• Avoid if you have a lung disease or breathing problems.
• This medication may cause dizziness; do not drive or operate machinery until you know how it affects you.
• Elderly patients should be closely monitored due to increased risk of adverse effects.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Keep out of reach of children and pets.

Following are the drug interactions for Concentrated Nitric Oxide 12mg Tablet:

• Interaction with diuretics, such as furosemide, can lead to increased risk of dehydration and electrolyte imbalances.
• May reduce the effectiveness of medications used for erectile dysfunction, including sildenafil and tadalafil.
• Nitric oxide can interact with nitrates and similar medications, causing a significant drop in blood pressure.
• Increased risk of hypotension when combined with angiotensin-converting enzyme (ACE) inhibitors like lisinopril.
• Drugs metabolized by the liver, like midazolam, may have altered effects when taken with nitric oxide.
• Concomitant use with phosphodiesterase-5 inhibitors (e.g., vardenafil) may result in enhanced vasodilatory effects.
• Caution is advised when combining with medications that affect the cardiovascular system, such as beta-blockers, to avoid potential blood pressure fluctuations.

Following are the food interactions for Concentrated Nitric Oxide 12mg Tablet:

• Avoid excessive consumption of foods rich in nitrates and nitrites, such as processed meats, as they can increase nitric oxide levels in the body, potentially leading to increased blood pressure and other cardiovascular issues.
• Limit the intake of high-sugar foods and beverages, as sugar can reduce the bioavailability of nitric oxide, hindering its effectiveness.
• Consuming a diet rich in antioxidants, including fruits and vegetables, can support nitric oxide production and overall cardiovascular health.
• Dark chocolate and cocoa contain flavonoids that can help improve nitric oxide bioavailability and promote healthy blood flow.
• Beets and beetroot juice are natural sources of nitrates, which can be converted into nitric oxide in the body, aiding in blood vessel dilation and improved circulation.
• Green leafy vegetables like spinach and kale provide nitrates and essential nutrients that support nitric oxide production and cardiovascular function.
• Citrus fruits like oranges and lemons are rich in vitamin C, which can help protect nitric oxide from degradation, ensuring its effectiveness in the body.
• Avoid high-fat meals as they may delay the absorption of nitric oxide supplements, potentially reducing their efficacy.

Store Concentrated Nitric Oxide 12mg Tablets in a secure and dry location, away from direct sunlight, moisture, and extreme temperatures. Ensure the tablets remain in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to store them in bathrooms or near heat-emitting appliances to preserve their effectiveness. Regularly check the expiration date, and if the tablets are no longer needed or have expired, proper disposal is essential. Avoid flushing them down the toilet or sink; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep this medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Concentrated Nitric Oxide 12mg Tablet:

• Consult your doctor before taking this medication for personalized advice.
• Take the tablet as directed by your healthcare professional.
• Swallow the tablet whole with a full glass of water, preferably at the same time daily.
• Avoid crushing, chewing, or breaking the tablet to preserve its effectiveness.
• Maintain a consistent medication schedule for best results.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.