Nitromint (2.6mg) 60 Retard Tablets

Nitroglycerin, the active ingredient in the 2.6mg tablet, exerts its therapeutic effects primarily through its conversion to nitric oxide (NO) in the body. This process occurs after the drug is metabolized by enzymes, particularly glutathione S-transferases, in the smooth muscle cells of blood vessels. Nitric oxide is a potent vasodilator, meaning it relaxes the smooth muscle cells within the vascular walls. This relaxation leads to the dilation of both arteries and veins, resulting in decreased vascular resistance and improved blood flow. The reduced vascular resistance subsequently lowers blood pressure, reducing the workload on the heart and decreasing the oxygen demand of the cardiac muscle. This mechanism is particularly beneficial in conditions where increased blood flow is desired, such as in the treatment of angina pectoris, where improved blood flow to the heart can alleviate chest pain.

vasodilator.

Tablet

The following are the uses of Nitroglycerine 2.6mg Tablet:

• Used for relieving chest pain in conditions like Angina.
• Used for reducing the frequency and severity of angina attacks.
• Used for improving exercise tolerance in patients with heart conditions.
• Used to prevent chest pain during activities or stress.
• Used as a short-term treatment for rapid heart rate (tachycardia).
• Used in emergency situations to treat severe heart failure.
• Used to manage symptoms of heart disease before and after certain procedures.

In the case of an overdose of Nitroglycerine 2.6mg Tablets, several symptoms may occur, including severe headaches, dizziness, fainting, and a sudden drop in blood pressure. This can lead to a rapid heartbeat and difficulty breathing. It is crucial to seek immediate medical assistance if an overdose is suspected, as prompt treatment can help manage these symptoms and prevent potential complications. Ingesting multiple tablets or exceeding the prescribed dosage may result in these adverse effects, warranting urgent medical intervention.

In the case of a missed dose of Nitroglycerine 2.6mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for further guidance on how to safely resume your medication. It is crucial to maintain a consistent dosing routine for optimal effectiveness.

To use Nitroglycerine 2.6mg Tablets, place the tablet under your tongue (sublingually) or between your cheek and gum (buccally) and allow it to dissolve completely, following the instructions provided by your healthcare professional.

Following are the conditions when Nitroglycerin 2.6mg Tablet should not be administered:

• Should not be used in individuals with a known allergy to Nitroglycerin or other nitrates.
• Contraindicated in patients with severe anemia, as it may worsen oxygen delivery.
• Not recommended for individuals with certain heart conditions, such as severe aortic valve stenosis or hypertrophic cardiomyopathy.
• Should not be used in patients with increased intracranial pressure or head injuries.
• Contraindicated during acute myocardial infarction with low blood pressure (hypotension).

The side effects of Nitroglycerine 2.6mg Tablet may include:

• Severe headaches
• Dizziness or lightheadedness
• Nausea and vomiting
• Skin rashes or itching
• Rapid or irregular heartbeat (palpitations)
• Low blood pressure (hypotension)
• Flushing or warmth in the face
• Weakness or fatigue

Following are the precautions and warnings for Nitroglycerine 2.6mg Tablet:

• Do not take this medication if you have severe anemia, recent head injury, or increased intracranial pressure, as it can worsen these conditions.
• Individuals with a known allergy to nitroglycerin or other nitrates should avoid this medication to prevent allergic reactions.
• Patients with hypotension (low blood pressure) should use with caution as it may cause a further drop in blood pressure.
• Elderly patients may be more sensitive to the effects and should monitor for side effects closely.
• It is important to avoid alcohol consumption while taking this medication as it can enhance the hypotensive effects.
• If you experience severe or persistent headaches during treatment, consult your doctor as it may indicate a tolerance to the medication.
• Patients should not abruptly discontinue this medication; follow your doctor's instructions for tapering off to prevent withdrawal symptoms.

Following are the drug interactions for Nitroglycerin 2.6mg Tablet:

• Alcohol and other vasodilators may lead to excessive blood pressure drop and increased side effects.
• Sildenafil and similar medications can cause severe hypotension and potential cardiac issues.
• Beta-blockers may counteract the effects of nitroglycerin and lead to reduced efficacy.
• Calcium channel blockers can enhance the vasodilatory effects, requiring close monitoring.
• Certain antidepressants (e.g., SSRIs) may increase nitroglycerin's effects and risk of side effects.
• Drugs metabolized by the liver, like phenytoin, can have their levels affected by nitroglycerin.
• Nitroglycerin may interact with diuretics, especially loop diuretics, increasing their effects.

Following are the food interactions for Nitroglycerin 2.6mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Nitroglycerin in the blood, leading to potential side effects.
• Alcohol intake is not recommended with Nitroglycerin as it may cause excessive dizziness and lightheadedness, and can also increase the drug's effects.
• High-fat meals may delay the absorption of Nitroglycerin, potentially reducing its effectiveness.
• Caffeine-rich foods and beverages should be limited as they may counteract the medication's effects and increase heart rate and blood pressure.
• Avoid aged cheeses as they can interfere with Nitroglycerin's effectiveness by increasing blood pressure.
• Avoid consuming large amounts of salt as it may reduce the medication's effectiveness and worsen hypertension.
• Consuming potassium-rich foods like bananas and oranges is beneficial as Nitroglycerin can deplete potassium levels.
• Ensure adequate fluid intake to maintain hydration, especially if experiencing diarrhea or vomiting.

Nitroglycerine 2.6mg Tablets should be stored in a secure and controlled environment, preferably in a cool and dry place, away from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to keep the tablets away from heat sources like heaters or ovens, as temperature fluctuations can impact their effectiveness. Always check the expiration date, and dispose of any unused or outdated medication responsibly. Do not flush or pour them down the drain; instead, consult your pharmacist for safe disposal guidelines. Ensure the tablets are stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Nitroglycerine 2.6mg Tablet:

• Consult your doctor for the correct dosage and duration of treatment.
• Take the tablet as prescribed, usually placed under the tongue.
• Allow the tablet to dissolve completely, do not chew or swallow it.
• If you experience dizziness, sit or lie down until you feel better.
• Avoid driving or operating machinery if you feel dizzy or lightheaded.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Keep the medication out of reach of children and pets.