NOBESE 15MG CAP

NOBESE 15MG CAP

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  • Manufacturer GETZ PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Sibutramine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Sibutramine 15MG Capsule primarily exerts its anorectic effect through the inhibition of neuronal reuptake of serotonin, norepinephrine, and dopamine. It acts as a serotonin-norepinephrine reuptake inhibitor (SNRI), leading to increased levels of these neurotransmitters in the synaptic cleft. By enhancing serotoninergic activity, sibutramine reduces appetite and promotes satiety, while its impact on norepinephrine and dopamine contributes to increased energy expenditure and metabolic rate. This combination of effects results in a reduced desire to eat and an increase in calorie burning, thereby aiding in weight loss.

  • Ingredients

    Sibutramine
  • Drug Class

    Appetite Suppressant

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Sibutramine 15MG Capsule:

    • Used for weight management by reducing appetite and increasing feelings of fullness.
    • Used to support weight loss in obese or overweight individuals, especially those with associated health risks.
    • Used to enhance metabolism, helping the body burn calories more efficiently.
    • Used to control binge eating and manage food cravings, aiding in portion control.
    • Used as part of a comprehensive weight loss program that includes diet, exercise, and lifestyle modifications.
    • Used to prevent weight regain after initial weight loss, helping to maintain long-term results.
    • Used to improve cardiovascular risk factors associated with obesity, such as high blood pressure and cholesterol levels.
    • Used to boost energy levels, which can facilitate increased physical activity and calorie expenditure.
  • In case of Overdose

    In the case of an overdose of Sibutramine 15MG Capsules, individuals may experience severe side effects such as rapid heartbeat, high blood pressure, seizures, hallucinations, and even cardiac arrest. It is crucial to seek immediate medical assistance if an overdose is suspected. Symptoms may vary, but prompt action is necessary to prevent potential life-threatening complications. Medical professionals should be informed about the dosage taken, and they will provide appropriate treatment to manage the overdose and minimize its impact on the body.

  • Missed Dose

    In the case of a missed dose of Sibutramine 15MG Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule safely.

  • How To Use

    To take Sibutramine 15MG Capsule, swallow the capsule whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, without crushing or chewing it.

  • When Not to Use

    Following are the conditions or circumstances when Sibutramine 15MG Capsule should not be taken:

    • Must not be taken by individuals with a known allergy or hypersensitivity to Sibutramine or any of its inactive ingredients.
    • Contraindicated in patients with a history of cardiovascular disease, including coronary artery disease, stroke, or uncontrolled high blood pressure.
    • Should not be used in patients with a history of an eating disorder such as anorexia nervosa or bulimia.
    • Not suitable for individuals with a history of seizures or epilepsy.
    • Should be avoided in patients with a history of drug abuse or dependence.
    • Contraindicated in patients taking certain medications, such as monoamine oxidase inhibitors (MAOIs), antidepressants, or other weight-loss drugs.
    • Not recommended for individuals with glaucoma or increased intraocular pressure.
    • Must not be used in patients with severe liver or kidney impairment.
    • Should be discontinued if significant increases in blood pressure or heart rate occur during treatment.
  • Side Effects

    The side effects of Sibutramine 15MG Capsule may include:

    • Dry mouth
    • Constipation
    • Nausea
    • Headache
    • Dizziness
    • Insomnia (difficulty sleeping)
    • Increased blood pressure
    • Rapid heartbeat
  • Precautions & Warnings

    Following are the precautions and warnings for Sibutramine 15MG Capsule:

    • Not recommended for individuals with a history of cardiovascular disease, including hypertension, as it may increase blood pressure and heart rate.
    • Patients with a history of stroke, arrhythmias, or peripheral arterial disease should not use this medication.
    • Caution is advised for those with a history of seizures, as Sibutramine may lower the seizure threshold.
    • Not suitable for individuals with a history of eating disorders such as anorexia or bulimia.
    • Should be used with caution in patients with glaucoma, as it may increase intraocular pressure.
    • May cause dry mouth, so patients should maintain good oral hygiene to prevent dental problems.
    • Not recommended for use in patients under 18 years old and over 65 years old.
  • Drug Interactions

    Following are the drug interactions for Sibutramine 15MG Capsule:

    • Monoamine oxidase inhibitors (MAOIs) should not be used concurrently due to the risk of serious adverse reactions, including serotonin syndrome.
    • Serotonergic drugs like SSRIs, SNRIs, or triptans may increase the risk of serotonin syndrome when combined with Sibutramine.
    • Blood pressure may be elevated when used with other medications that increase blood pressure or have sympathomimetic properties.
    • The effect of Sibutramine may be reduced by medications that induce certain liver enzymes, leading to decreased efficacy.
    • Concomitant use with anticoagulants may increase the risk of bleeding.
    • Sibutramine may interact with anticonvulsants, potentially affecting seizure control.
    • Drugs that affect the central nervous system, such as opioids or benzodiazepines, can increase the risk of respiratory depression and sedation.
  • Food Interactions

    Following are the food interactions for Sibutramine 15MG Capsule:

    • Avoid consuming grapefruit and grapefruit juice as they can interfere with the metabolism of Sibutramine, potentially leading to increased drug levels in the body and heightened side effects.
    • Alcohol consumption should be minimized or avoided as it may enhance the sedative effects of Sibutramine, increasing the risk of dizziness, drowsiness, and impaired coordination.
    • High-fat meals can slightly delay the absorption of Sibutramine, but this does not significantly impact its overall effectiveness.
    • Caffeine intake should be moderated as Sibutramine may enhance its effects, potentially causing nervousness, insomnia, and increased heart rate.
    • Avoid energy drinks and excessive amounts of caffeine-containing products to prevent potential cardiovascular side effects.
    • Maintain a balanced diet, as Sibutramine can increase blood pressure and heart rate, and a healthy diet can support overall cardiovascular health.
    • Ensure adequate hydration by drinking enough water, especially during physical activities, to prevent dehydration.
    • Consult your healthcare provider for personalized dietary advice while taking Sibutramine to optimize treatment outcomes.
  • Storage/Disposal

    Sibutramine 15MG Capsules should be stored in a secure and dry place, preferably in a medicine cabinet, at room temperature, ensuring it remains between 68°F and 77°F (20°C and 25°C). Keep the capsules in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial to keep this medication out of the reach of children and pets to prevent accidental ingestion. When disposing of unused or expired Sibutramine capsules, do not throw them in the trash or flush them down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal, or consult a pharmacist for advice on safe disposal methods to protect the environment and prevent misuse.

  • Quick Tips, if any

    Following are the quick tips for Sibutramine 15MG Capsule:

    • Consult a doctor for a prescription and guidance before taking this medication.
    • Swallow the capsule whole; do not crush or chew it.
    • Take the capsule as directed, typically once daily, with or without food.
    • Maintain a consistent daily routine for taking the medication.
    • Avoid alcohol consumption while using this medication.
    • Inform your doctor about all medications/supplements you're taking.
    • Do not share this medication with others; it is prescribed specifically for you.
    • Store in a cool, dry place, away from direct sunlight.

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