NORMOROL EXTRA CAP (30S)

Ubidecarenone, also known as Coenzyme Q10 (CoQ10), works by mimicking the naturally occurring compound coenzyme Q10 in the body. Its primary mechanism of action revolves around its role in the electron transport chain within the mitochondria, where it facilitates the transfer of electrons and participates in the production of adenosine triphosphate (ATP), the energy currency of cells. By enhancing cellular energy production, ubidecarenone supports the function of organs with high energy demands, such as the heart and muscles. Additionally, its antioxidant properties help neutralize harmful free radicals, reducing oxidative stress and protecting cellular membranes and DNA from damage.

Coenzyme Q10.

Capsule

The following are the uses of Ubidecarenone Capsule:

• Used for supporting heart health and improving heart function.
• Used for enhancing energy production in cells, particularly in muscles.
• Used for reducing oxidative stress and acting as an antioxidant.
• Used for potentially improving exercise performance and endurance.
• Used for supporting brain health and cognitive function.
• Used for maintaining healthy blood sugar levels.
• Used for promoting skin health and reducing signs of aging.
• Used for boosting the immune system.

In the case of an overdose of Ubidecarenone Capsules, it is important to remain calm and seek immediate medical assistance. Inform the healthcare provider about the specific details of the overdose, including the number of capsules consumed. They may induce vomiting or administer activated charcoal to prevent further absorption. Close monitoring of vital signs and symptoms is necessary to manage any adverse effects. Prompt action and medical care are essential to ensure the best possible outcome.

In the case of a missed dose of Ubidecarenone capsules, it is generally advised to take the missed dose as soon as you remember, provided it is not too close to your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you frequently miss doses or are unsure about how to manage missed doses to ensure the medication's effectiveness.

To take Ubidecarenone capsules, swallow the capsule whole with a full glass of water, preferably with a meal, once or twice a day as directed by your healthcare professional.

Following are the conditions when Ubidecarenone Capsule should not be used:

• Should not be used in individuals with a known sensitivity or allergy to Coenzyme Q10 or any of the excipients in the capsule.
• Not suitable for individuals with a history of severe cardiovascular disease, such as recent heart attack or unstable angina.
• Contraindicated in patients with a bleeding disorder or those taking anticoagulant medications.
• Should be avoided in individuals with uncontrolled high blood pressure.
• Not recommended for patients with a history of liver or kidney disease.
• Should not be used during pregnancy or breastfeeding, unless advised by a healthcare professional.
• Discontinue use if you experience any skin rashes, itching, or severe gastrointestinal symptoms.

The side effects of Ubidecarenone Capsule may include:

• Nausea and vomiting
• Stomach pain
• Diarrhea
• Skin rash or itching
• Dizziness
• Insomnia
• Fatigue
• Increased liver enzymes

Following are the precautions and warnings for Ubidecarenone Capsule:

• Not recommended for individuals with a known hypersensitivity or allergy to Ubidecarenone or any of the excipients in the capsule.
• Patients with a history of blood clotting disorders or those taking anticoagulant medications should exercise caution and consult a healthcare professional before use.
• May cause mild gastrointestinal side effects like nausea or stomach upset in some individuals.
• Those with a history of liver disease should use with caution and under medical supervision as it may affect liver function.
• Ubidecarenone may lower blood sugar levels, so patients with diabetes should monitor their blood sugar closely.
• Patients should inform their doctor about all medications they are taking to avoid potential drug interactions.
• Pregnant and breastfeeding women should consult their healthcare provider before using Ubidecarenone to ensure the benefits outweigh any potential risks.

Following are the drug interactions for Ubidecarenone Capsule:

• Ubidecarenone may reduce the anticoagulant effect of warfarin, potentially requiring adjustment of warfarin dosage.
• Concomitant use with beta-blockers like metoprolol or propranolol might reduce the effectiveness of these medications in treating hypertension.
• It can decrease the bioavailability of certain medications, such as lipid-lowering agents (e.g., gemfibrozil), potentially reducing their effectiveness.
• Ubidecarenone may increase the risk of bleeding when taken with antiplatelet drugs like clopidogrel or nonsteroidal anti-inflammatory drugs (NSAIDs).
• Antipsychotic medications, such as haloperidol or risperidone, may interact with Ubidecarenone, leading to increased side effects.
• It could potentially reduce the efficacy of chemotherapy drugs by protecting cancer cells from oxidative damage.
• Ubidecarenone may enhance the immune-suppressing effects of medications like ciclosporin or tacrolimus.

Following are the food interactions for Ubidecarenone Capsule:

• Ubidecarenone may interact with high-fat meals, leading to reduced absorption. It is advisable to take the capsule at least 2 hours before or after a high-fat meal to ensure optimal absorption.
• Avoid consuming excessive amounts of dairy products, as they may interfere with the absorption of Ubidecarenone. This is because dairy products are high in calcium, which can bind to the active ingredient and reduce its bioavailability.
• Grapefruit and grapefruit juice should be consumed with caution as they may alter the metabolism of Ubidecarenone. These fruits contain compounds that can inhibit the CYP3A4 enzyme, affecting the breakdown and elimination of the medication.
• Limit caffeine intake, as it may enhance the metabolism of Ubidecarenone, potentially reducing its effectiveness. Consider reducing coffee, tea, and energy drinks while taking this medication.
• Alcohol may interfere with the effectiveness of Ubidecarenone, and excessive alcohol consumption should be avoided. Alcohol can affect liver function, which is crucial for metabolizing and eliminating the medication.
• Green, leafy vegetables and vegetable oils rich in vitamin K should be consumed moderately. Ubidecarenone can interact with vitamin K, potentially affecting blood clotting processes.
• Consuming a balanced diet with a variety of fruits, vegetables, and whole grains is generally recommended to support overall health while taking Ubidecarenone. A healthy diet can contribute to the medication's benefits.
• Always consult your healthcare provider for personalized advice regarding food interactions, as individual responses may vary.

Ubidecarenone capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the capsules to extreme temperatures, so avoid storing them in the bathroom or near heat sources. Regularly check the expiration date, and if the capsules are past their prime or no longer needed, proper disposal is essential. Do not dispose of them in wastewater or the environment; consult a pharmacist or healthcare professional for guidance on safe disposal practices. Keep the medication securely stored, out of the reach of children, to prevent accidental consumption.

Following are the quick tips for Ubidecarenone Capsule:

• Consult your doctor before taking Ubidecarenone, especially if you have a medical condition or are on other medications.
• Take the capsule with a full glass of water for easy swallowing.
• Maintain a consistent daily routine for taking the capsule.
• Ubidecarenone can be taken with or without food, but taking it with a meal may reduce the risk of stomach upset.
• Avoid crushing or chewing the capsule; swallow it whole for optimal absorption.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.
• Regularly monitor your health and inform your doctor of any unusual symptoms while taking Ubidecarenone.
• Do not share your medication with others, even if their symptoms seem similar.