NUCARB TAB

Calcium Sennosides and Rhubarb extract in this tablet formulation work synergistically as stimulant laxatives. Sennosides, derived from senna leaves, are converted by intestinal bacteria into rheinanthrone, which directly stimulates intestinal mucosa and induces peristalsis. This increases intestinal motility and promotes bowel movements. Rhubarb extract contains anthraquinones, such as rhein and emodin, which have a similar stimulant effect on the intestinal tract. These compounds irritate the intestinal lining, causing contractions and accelerating the passage of stool through the colon, thereby relieving constipation.

Calcium Sennosides 0.2, Rhubarb extract 250mg

Laxative

Tablet

The following are the uses of Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet:

• Used for relieving occasional constipation and promoting bowel movements.
• Used as a laxative to ease digestive discomfort and encourage regularity.
• Used for gentle cleansing of the colon to support digestive health.
• Used for short-term relief from constipation-related symptoms.
• Used to soften stools, making them easier to pass.
• Used to stimulate intestinal contractions for effective bowel evacuation.
• Used as a natural remedy to promote bowel function.

In the case of an overdose of Calcium Sennosides 0.2 and Rhubarb extract 250mg Tablets, individuals may experience gastrointestinal distress, including severe diarrhea, abdominal pain, and cramping. Other symptoms can include nausea, vomiting, and electrolyte imbalances, which can lead to dehydration and muscle weakness. Prompt medical attention is necessary, and individuals should seek advice from a healthcare professional or poison control center, who can provide guidance on managing the symptoms and preventing further complications.

In the case of a missed dose of Calcium Sennosides 0.2 or Rhubarb extract 250mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to help you remember to take your medication as prescribed.

To take Calcium Sennosides 0.2mg and Rhubarb extract 250mg tablets, swallow the tablet whole with a full glass of water, usually at bedtime or as directed by your healthcare provider, without crushing or chewing, following the dosage instructions provided by your doctor or pharmacist.

The following are the conditions when Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet should not be taken:

• Should not be used by individuals with a known allergy to any of its components, including sennosides, calcium, or rhubarb.
• Contraindicated in individuals with bowel obstruction, severe dehydration, or undiagnosed abdominal pain.
• Not suitable for individuals with conditions such as Crohn's disease, ulcerative colitis, appendicitis, or other inflammatory bowel diseases.
• Should be avoided in individuals with a history of gastrointestinal surgery or recent gastrointestinal procedures.
• Not recommended for individuals with severe constipation caused by a potential underlying medical condition until the condition is treated.
• Should not be used by individuals with heart disease, as it may cause electrolyte imbalances.
• Contraindicated in individuals with kidney disease, as it may affect kidney function.

The side effects of Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet may include:

• Abdominal pain or cramps
• Diarrhea
• Nausea and vomiting
• Electrolyte imbalance (especially with prolonged use)
• Weakness or fatigue
• Skin rash or itching
• Allergic reactions (rare)
• Excessive bowel movements

Following are the precautions and warnings for Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet:

• Do not use if you have an allergy or hypersensitivity to sennosides, rhubarb, or any other ingredients in the tablet.
• Patients with gastrointestinal conditions like intestinal obstruction, Crohn's disease, ulcerative colitis, or appendicitis should not take this medication.
• Caution is advised for individuals with kidney or liver disease, as the dosage may need adjustment.
• This medication can cause dehydration and electrolyte imbalances, especially with prolonged use; regular monitoring is necessary.
• Avoid using other stimulant laxatives or herbal products for constipation while taking this medication.
• Elderly patients may be more sensitive to the effects and should use with caution.
• If symptoms persist or worsen, or if abdominal pain, nausea, or vomiting occur, discontinue use and seek medical advice.
• Not recommended for long-term use; prolonged use may lead to dependence and bowel function impairment.

Following are the drug interactions for Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet:

• Prolonged use with other stimulant laxatives or diuretics can lead to electrolyte imbalance and potentially serious cardiac complications.
• May decrease the absorption of other medications, especially those taken within an hour of ingestion. It is recommended to space out the doses of this medication and other drugs.
• This medication may interact with antacids, reducing the effectiveness of both drugs.
• Can interact with cardiac glycosides, increasing the risk of cardiac arrhythmias. Close monitoring is advised.
• When used with other nephrotoxic drugs, it may increase the risk of kidney damage.
• May enhance the effects of blood thinners, requiring close monitoring of coagulation parameters.
• Caution is advised when combining with immunosuppressants, as it may increase the risk of immunosuppression-related side effects.

Following are the food interactions for Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet:

• Avoid consuming excessive amounts of dairy products like milk, cheese, and yogurt as these are high in calcium, which can interfere with the absorption of Calcium Sennosides.
• Limit or avoid consuming high-fiber foods like whole grains, legumes, and certain fruits and vegetables during treatment, as these can reduce the effectiveness of the medication.
• Alcohol should be avoided as it can cause dehydration and worsen constipation, reducing the efficacy of the medication.
• Caffeine intake should be monitored as it can stimulate bowel movements and potentially interact with the laxative effect of the medication.
• Avoid consuming foods and beverages with high sugar content, especially artificial sweeteners, as they can interfere with the medication's action and potentially cause gastrointestinal discomfort.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of certain compounds in the medication.
• Staying well-hydrated by drinking adequate water is essential to support the laxative effect of the medication and prevent dehydration.
• Consider reducing fatty food consumption as it can slow digestion and potentially interact with the medication's effectiveness.

Calcium Sennosides 0.2, Rhubarb extract 250mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The tablets must be kept in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to avoid storing them in hot or humid environments like bathrooms or near heat sources, as temperature fluctuations can impact their effectiveness. Always check the expiration date, and if the tablets are past their prime, dispose of them appropriately. Never flush or pour them into drainage systems; instead, seek advice from a pharmacist or healthcare professional for safe disposal practices. Additionally, keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Calcium Sennosides 0.2, Rhubarb extract 250mg Tablet:

• Consult your healthcare provider for personalized dosage instructions.
• Swallow the tablet whole with a glass of water for better effectiveness.
• Take the tablet as directed, preferably at the same time each day.
• Do not crush or chew the tablet, as it may alter its absorption.
• Avoid taking with dairy products or antacids, as they may interfere with absorption.
• If you experience stomach discomfort, inform your healthcare provider.
• Store the medication in a cool, dry place, away from direct sunlight.