Num Cain 15gm Cream

The mechanism of action of Lidocaine and Tetracaine Cream involves the inhibition of voltage-gated sodium channels in nerve cell membranes. Both lidocaine and tetracaine are local anesthetic agents that work by blocking the initiation and conduction of nerve impulses. When applied topically, they penetrate the skin and reach the sensory nerve endings. By binding to specific sites on the sodium channels, they prevent the rapid influx of sodium ions that is necessary for the generation and propagation of action potentials. This blockade of sodium channels leads to a temporary loss of sensation, effectively numbing the area and providing local anesthesia. The combination of lidocaine and tetracaine in the cream enhances the anesthetic effect, as they have different molecular structures and may interact with sodium channels at distinct sites, resulting in a more comprehensive and prolonged anesthesia.

Lidocaine, Tetracaine

Local anesthetic

Cream

The following are the uses of Lidocaine, Tetracaine Cream:

• Used for numbing the skin before minor medical procedures
• Used for providing local anesthesia during small surgical interventions
• Used for relieving pain and itching associated with minor cuts, scrapes, and insect bites
• Used for reducing discomfort during insertion of needles or catheters
• Used for managing pain from minor burns, sunburns, and skin allergies
• Used for temporary pain relief in conditions like shingles and diabetic neuropathy
• Used for facilitating painless removal of superficial skin lesions

In the case of an overdose of Lidocaine and Tetracaine Cream, symptoms may include dizziness, ringing in the ears, confusion, and seizures. Overapplication or ingestion of the cream can lead to severe adverse effects. If an overdose occurs, seek medical assistance promptly. Treatment may involve monitoring vital signs, managing seizures, and providing supportive care. It is crucial to use the cream as directed to prevent such incidents.

In the case of a missed dose of Lidocaine and Tetracaine Cream, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule and ensure effective pain management.

To apply Lidocaine, Tetracaine Cream, clean and dry the affected area, then gently rub a thin layer of the cream onto the skin, ensuring complete coverage, and avoid getting the cream in the eyes or mouth, and wash your hands after application.

Here are the situations or conditions when Lidocaine and Tetracaine Cream should not be used:

• Must not be applied to individuals with a known allergy to Lidocaine, Tetracaine, or any local anesthetics.
• Avoid using the cream on areas with broken or infected skin.
• Not suitable for individuals with a history of severe skin reactions or skin disorders.
• Should not be used on mucous membranes or inside the eyes, ears, nose, or mouth.
• Contraindicated in patients with a rare hereditary problem of galactose intolerance.
• Not recommended for individuals with a known metabolic disorder called glucose-galactose malabsorption.
• Avoid using the cream on skin areas with severe vascular disease or impaired circulation.
• Should not be applied to skin areas with active skin inflammation or dermatitis.
• Avoid using it on skin conditions caused by exposure to sunlight or UV light.

The side effects of Lidocaine, Tetracaine Cream may include:

• Skin redness
• Itching or rash at the application site
• Swelling or inflammation
• Allergic reactions (hives, difficulty breathing, swelling of the face/lips/tongue)
• Numbness or tingling sensation
• Skin irritation or burning
• Temporary skin discoloration
• Increased sensitivity to touch

Following are the precautions and warnings:

• Lidocaine, Tetracaine Cream should not be used if you are allergic to local anesthetics or any of the cream's components.
• Avoid contact with eyes, nose, mouth, and other mucous membranes as it is intended for external use only.
• Wash your hands thoroughly before and after application to prevent accidental transfer to sensitive areas.
• Do not apply to open wounds, infected areas, or skin conditions like eczema or psoriasis without medical advice.
• This cream can cause temporary numbness, so avoid activities that require fine motor skills or coordination until the numbness wears off.
• Pregnant and breastfeeding women should consult a healthcare professional before using this cream.
• Keep out of reach of children and pets. Store it at room temperature, away from direct sunlight and moisture.

Following are the drug interactions for Lidocaine, Tetracaine Cream:

• Topical application of Lidocaine, Tetracaine Cream with other local anesthetics or products containing similar active ingredients may result in increased systemic absorption and potential toxicity.
• Lidocaine and Tetracaine can interact with Class III antiarrhythmic drugs (e.g., amiodarone), potentially prolonging cardiac conduction and increasing the risk of arrhythmias.
• Concomitant use with other vasoconstrictor drugs may enhance the vasoconstrictive effects and increase the risk of hypertension.
• The cream may interact with certain antibiotics, such as ciprofloxacin or moxifloxacin, affecting their absorption and efficacy.
• Caution is advised when using with other medications that lower the seizure threshold, as it may increase the risk of seizures.
• Lidocaine metabolism can be affected by drugs that induce or inhibit CYP3A4 enzymes, potentially altering its effectiveness and safety.
• Lidocaine, Tetracaine Cream should be used with caution in patients taking digoxin, as it may increase plasma levels of digoxin, requiring monitoring.

Following are the food interactions for Lidocaine, Tetracaine Cream:

• Avoid consuming alcohol during the use of this medication as it can increase the risk of side effects and may cause excessive drowsiness and dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of the medication, leading to increased blood levels and potential toxicity.
• Avoid caffeine-rich foods and beverages like coffee, tea, and energy drinks as they may enhance the absorption of the medication, leading to higher blood levels and potential adverse effects.
• Spicy foods should be consumed in moderation as they can irritate the skin, especially in areas where the cream is applied, causing discomfort and potential skin reactions.
• Avoid eating or drinking hot items, as they may increase blood flow to the application site and potentially enhance the absorption of the medication.
• Consuming fatty or greasy foods may delay the absorption of the medication, potentially reducing its effectiveness.
• Avoid excessive consumption of sugar and sugary foods, as they may promote bacterial growth and potentially delay wound healing in the treated area.
• It is generally recommended to maintain a balanced diet and stay well-hydrated to support overall skin health and aid in the healing process.

Lidocaine, Tetracaine Cream should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area. The cream should be kept at room temperature, away from direct sunlight, heat, and moisture, as exposure to these elements can affect its potency. It is crucial to store the cream in its original packaging, ensuring the label remains intact for easy identification and reference. When disposing of the cream, follow local regulations and guidelines for pharmaceutical waste disposal. Do not flush or pour the cream down the drain, as it can have environmental implications. Instead, contact your healthcare provider or pharmacist for guidance on safe disposal methods. Keep the cream out of reach of children and pets to prevent accidental exposure, and always practice responsible medication management. Proper storage and disposal of Lidocaine, Tetracaine Cream are essential to maintain its effectiveness and minimize potential risks.

Following are the quick tips for Lidocaine, Tetracaine Cream:

• Apply a thin layer of the cream to the affected area as directed by your doctor.
• Wash your hands before and after application to maintain hygiene.
• Gently rub the cream into the skin until it is completely absorbed.
• Avoid applying the cream to open wounds or broken skin.
• Do not cover the treated area with bandages or tight clothing.
• Inform your doctor if you experience severe burning, stinging, or irritation after application.
• Store the cream at room temperature, away from direct sunlight and moisture.