Nutraxin Vitamin B12 (1000mcg) 60 Chewable Tablets

Mannitol and Vitamin B12 (cyanocobalamin) have distinct mechanisms of action. Mannitol, an osmotic diuretic, primarily works by creating an osmotic gradient within the renal tubules, promoting the excretion of water and various solutes. This mechanism helps reduce intracranial pressure and intraocular pressure by drawing excess fluid from the brain and eye tissues into the bloodstream. Vitamin B12, on the other hand, is essential for DNA synthesis, red blood cell formation, and the proper functioning of the nervous system. It plays a crucial role in the formation of myelin, a protective sheath around nerve fibers, and aids in the metabolism of fatty acids and amino acids. Vitamin B12 deficiency can lead to anemia and neurological disorders, and supplementation with cyanocobalamin helps restore these vital functions.

Osmotic Diuretic, Vitamin B12 Supplement.

Tablet

The following are the uses of Mannitol, Vitamin B 12 Tablet:

• Used for treating fluid retention in the body, especially in the brain and eyes, reducing pressure.
• Used to prevent kidney failure in patients undergoing major surgery.
• Used for replenishing essential nutrients, particularly in cases of vitamin B12 deficiency, and supporting overall health.
• Used for treating diabetic ketoacidosis, a serious complication of diabetes.
• Used to enhance athletic performance and endurance, particularly in endurance sports.
• Used for managing certain metabolic disorders and genetic conditions.
• Used for improving nerve function and treating neurological disorders related to vitamin B12 deficiency.
• Used as a diagnostic tool for specific medical conditions, especially kidney function assessments.

In the case of an overdose of Mannitol, symptoms may include increased urination, dehydration, and electrolyte imbalances. It can also lead to a condition called hyponatremia, causing confusion, seizures, and in severe cases, coma. For Vitamin B12 tablets, overdoses are rare, but may result in mild side effects like nausea, headaches, and skin rashes. If you suspect an overdose, seek medical advice promptly. Prompt medical care is essential to address any potential complications.

In the case of a missed dose of Mannitol, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. For Vitamin B12 tablets, if you forget to take a dose, take it as soon as you remember, but if it's close to the time for your next dose, skip the missed dose and resume your regular schedule. It's important not to double the dose to make up for a missed one.

To take the Mannitol, Vitamin B12 Tablet, place the tablet on your tongue and allow it to dissolve completely, preferably at the same time each day, without chewing or crushing it, following the dosage instructions provided by your healthcare professional.

Here are the conditions or situations when Mannitol, Vitamin B12 Tablet should not be used:

• Avoid if you have a known allergy or sensitivity to mannitol or any of the tablet's components.
• Not suitable for patients with severe renal impairment or active renal disease.
• Should not be used in patients with congestive heart failure or severe pulmonary congestion.
• Contraindicated in individuals with intracranial bleeding or increased intracranial pressure.
• Not recommended for patients with severe dehydration or those with conditions causing fluid and electrolyte imbalances.
• Avoid in patients with severe gastrointestinal obstruction or conditions causing intestinal obstruction.

The side effects of Mannitol and Vitamin B12 Tablet may include:

• Increased urination
• Electrolyte imbalance (especially in prolonged use)
• Nausea and vomiting
• Headache
• Dizziness
• Allergic reactions (skin rash, itching, swelling)
• Temporary pain or discomfort at the injection site (for Vitamin B12 injections)
• Diarrhea

Following are the precautions and warnings for Mannitol, Vitamin B12 Tablet:

• Patients with kidney disease or any degree of renal impairment should use with caution and under medical supervision, as mannitol can affect kidney function.
• Not recommended for patients with active peptic ulcers or a history of peptic ulcer disease due to potential irritation of the gastrointestinal tract.
• This medication may cause dizziness or lightheadedness, so patients should rise slowly from a sitting or lying position to prevent falls.
• Diabetic patients should be aware that mannitol can affect blood sugar levels, and regular monitoring is necessary.
• Elderly individuals may be more sensitive to the effects of mannitol, especially regarding kidney function and fluid balance.
• If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medication.
• This medication may cause temporary blurred vision or reduced visual acuity, so caution is advised when performing tasks that require clear vision.

Following are the drug interactions for Mannitol, Vitamin B12 Tablet:

• Mannitol may interact with other diuretics, increasing the risk of electrolyte imbalances and dehydration. Close monitoring of fluid and electrolyte levels is necessary.
• Vitamin B12 absorption can be reduced by prolonged use of proton pump inhibitors (PPIs) and H2 blockers, potentially leading to decreased effectiveness.
• Antibiotics like metformin and chloramphenicol can interfere with Vitamin B12 absorption, requiring dosage adjustments.
• Use with alcohol may increase the risk of gastrointestinal side effects and should be avoided.
• Mannitol can affect the absorption of other medications, especially those with a narrow therapeutic index, requiring careful monitoring.
• Certain medications metabolized by the liver may have altered effectiveness when taken with Vitamin B12, as it can influence liver function.
• The effectiveness of anti-diabetic medications may be impacted by Mannitol's effects on blood glucose levels, necessitating close monitoring.

Following are the food interactions for Mannitol, Vitamin B 12 Tablet:

• Mannitol may cause a laxative effect, so limiting foods with natural laxative properties like prunes, figs, or high-fiber foods is advisable to prevent excessive bowel movements.
• Avoid excessive alcohol consumption as it may interfere with vitamin B12 absorption and increase the risk of gastrointestinal side effects.
• Vitamin B12 absorption can be hindered by foods containing polyphenols, such as tea, coffee, and some legumes, so consider separating their intake from the medication.
• High-protein foods like meat and eggs can enhance vitamin B12 absorption, ensuring its effectiveness.
• Mannitol may cause dehydration, so ensure adequate fluid intake, especially when consuming diuretic foods like watermelon, cucumber, and herbal teas.
• Avoid or limit foods with high sugar content, as mannitol can have a sweetening effect, and excessive sugar intake should be monitored.
• There are no direct food interactions with mannitol's effectiveness, but maintaining a balanced diet is essential for overall health.

Mannitol and Vitamin B12 Tablets should be stored in a cool and dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight by keeping them in their original container tightly sealed. It is crucial not to store them in the bathroom or kitchen, as these areas may expose the medication to temperature fluctuations and humidity. When disposing of expired or unused tablets, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines or consult a pharmacist for safe disposal methods to prevent environmental contamination. Keep the medication away from children and pets to ensure their safety.

Following are the quick tips for Mannitol, Vitamin B12 Tablet:

• Consult your doctor for the right dosage and duration tailored to your health needs.
• Swallow the tablet whole, avoiding crushing or chewing for optimal absorption.
• Take the tablet on an empty stomach, preferably 1 hour before or 2 hours after meals.
• Maintain a consistent schedule by taking your tablet at the same time daily.
• Ensure you complete the full course of medication as prescribed.
• Stay well-hydrated while taking Mannitol to support its diuretic effect.
• If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Consume the tablet orally, swallowing it whole without chewing or crushing.
• Take the tablet on an empty stomach, ideally 1 hour before or 2 hours after meals.
• Maintain a consistent routine by taking your tablet at the same time each day.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Ensure you complete the full course as prescribed by your healthcare provider.
• If you experience any allergic reactions or side effects, seek medical advice promptly.
• Keep the medication out of reach of children to prevent accidental consumption.