Oflocin-200 10 Tablets

Ofloxacin, a synthetic chemotherapeutic antibiotic, exerts its bactericidal effect by inhibiting DNA gyrase and topoisomerase IV, essential bacterial enzymes responsible for DNA replication, transcription, and repair. This inhibition leads to the disruption of bacterial DNA synthesis, preventing the bacteria from replicating and repairing their genetic material. By targeting these vital enzymes, ofloxacin effectively interferes with the fundamental processes required for bacterial survival and proliferation, ultimately resulting in the death of the susceptible bacteria.

Fluoroquinolone antibiotic.

Tablet

The following are the uses of Ofloxacin Tablet:

• Used for treating bacterial infections, particularly those affecting the respiratory tract, skin, and urinary system.
• Used for pneumonia, bronchitis, and sinus infections.
• Used for certain sexually transmitted infections like gonorrhea.
• Used for skin infections such as cellulitis and abscesses.
• Used for urinary tract infections, including bladder and kidney infections.
• Used for eye infections, such as conjunctivitis and corneal ulcers.
• Used for bone and joint infections, providing relief from symptoms.

In the case of an overdose of Ofloxacin Tablets, several symptoms may occur, including nausea, vomiting, dizziness, and headache. The severity of these symptoms can vary depending on the amount ingested. It is important to seek medical advice immediately if an overdose is suspected. Treatment may involve supportive care and managing any adverse effects. Prompt action and medical intervention are key to minimizing the risks associated with Ofloxacin Tablet overdoses.

In the case of a missed dose of Ofloxacin Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for advice on how to safely resume your medication regimen. Remember, maintaining a consistent dosing schedule is crucial for the effectiveness of Ofloxacin Tablet.

To take Ofloxacin Tablets, swallow the prescribed number of tablets whole with a full glass of water, preferably at the same time each day, without crushing or chewing, as directed by your healthcare professional.

Here are the conditions or situations when Ofloxacin Tablet should not be taken:

• Do not use if you have a known allergy or hypersensitivity to Ofloxacin or other quinolone antibiotics.
• Avoid if you have a history of myasthenia gravis, as it can worsen muscle weakness.
• Not suitable for patients with a history of tendon disorders or tendon rupture related to previous quinolone therapy.
• Contraindicated in individuals with epilepsy or a history of seizures, as it may lower the seizure threshold.
• Should not be used in patients with prolonged QT intervals or a history of cardiac arrhythmias.
• Avoid in patients with kidney disease or those on dialysis, as dosage adjustment is required.
• Not recommended for children, adolescents, pregnant women, and breastfeeding mothers due to potential risks.
• Do not use if you have a history of liver disease or if you currently have liver function abnormalities.
• Avoid prolonged exposure to direct sunlight or UV light while taking Ofloxacin, as it may increase sun sensitivity.

The side effects of Ofloxacin Tablet may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Dizziness
• Headache
• Skin rashes and itching
• Photosensitivity (increased sensitivity to sunlight)
• Sleep disturbances and insomnia

Following are the precautions and warnings for Ofloxacin Tablet:

• Do not take Ofloxacin if you have a known allergy to any quinolone antibiotics, as serious allergic reactions can occur.
• Ofloxacin should be used with caution in patients with kidney or liver disease, as dosage adjustments may be necessary.
• This medication can cause photosensitivity, so avoid excessive sunlight or UV light exposure, and protect your skin when outdoors.
• It may cause dizziness and lightheadedness, so caution is advised when driving or operating machinery.
• Pregnant and breastfeeding women should consult their doctor before taking Ofloxacin, as it may harm the unborn baby or pass into breast milk.
• Elderly patients may be more susceptible to tendon problems, including tendon rupture, so exercise caution and report any joint or tendon pain immediately.
• Ofloxacin may cause central nervous system effects, including seizures; it should be used with caution in patients with a history of seizures or conditions affecting the nervous system.
• Discontinue the medication and seek medical attention if you experience any severe side effects, such as rapid or irregular heartbeat, severe diarrhea, or signs of an allergic reaction.

Following are the drug interactions for Ofloxacin Tablet:

• Antacids containing magnesium or aluminum may reduce the absorption of Ofloxacin, so they should be taken at least 2 hours apart.
• Theophylline levels can be increased when used with Ofloxacin, potentially leading to toxicity.
• The risk of tendon rupture is higher when Ofloxacin is combined with corticosteroids.
• Concomitant use with non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system (CNS) stimulation and seizures.
• Ofloxacin may enhance the effects of oral anticoagulants, requiring close monitoring of prothrombin time.
• Probenecid can increase the concentration of Ofloxacin in the body, potentially increasing the risk of side effects.
• Sucralfate may decrease the absorption of Ofloxacin, so they should be taken at separate times.

Following are the food interactions for Ofloxacin Tablet:

• Avoid excessive caffeine intake as it may increase the risk of side effects, particularly nervousness and insomnia.
• Grapefruit and grapefruit juice consumption should be limited as they can interfere with the metabolism of Ofloxacin, leading to increased drug levels in the body and potentially more side effects.
• Alcoholic beverages should be avoided as they may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion.
• Consuming dairy products like milk, yogurt, or cheese close to taking Ofloxacin may decrease the absorption of the medication. It is best to separate them by a few hours.
• Avoid high-fat meals as they may delay the absorption of Ofloxacin, potentially reducing its effectiveness.
• Iron supplements and multivitamins containing minerals like zinc, magnesium, and calcium can hinder the absorption of Ofloxacin. Take them at different times.
• Vitamin K-rich foods like leafy green vegetables may reduce the effectiveness of Ofloxacin, especially in patients on anticoagulant therapy.
• Always follow the dosage instructions provided by your healthcare professional, as the timing of meals and medication intake can influence the drug's absorption and efficacy.

Ofloxacin Tablets should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and effectiveness. Avoid exposure to direct sunlight, excessive heat, or moisture, as these conditions can degrade the medication. Always check the expiration date, and do not use the tablets if they are expired. When it comes to disposal, do not flush or pour the medication down the drain. Instead, follow local guidelines or consult a healthcare professional for safe disposal methods to protect the environment. Keep the tablets out of children's reach to prevent accidental consumption.

Following are the quick tips for Ofloxacin Tablet:

• Take the tablet as directed by your doctor, usually once or twice daily.
• Swallow the tablet whole with a full glass of water, preferably at the same time each day.
• Take it at least 2 hours before or 2 hours after eating, as food may interfere with absorption.
• Do not crush, chew, or break the tablet, as it may affect its effectiveness.
• Complete the full course of medication even if you feel better; stopping early may lead to treatment failure.
• Avoid excessive sunlight and UV exposure; use sunscreen and protective clothing.
• Inform your doctor if you have any allergies or medical conditions before starting this medication.