Olanzia? Cap 5 MG 10's

Olanzia? Cap 5 MG 10's

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  • Manufacturer WERRICK PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Olanzapine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Olanzapine, a 5mg capsule, exerts its therapeutic effects primarily through its interaction with various neurotransmitter receptors in the brain. It acts as an antagonist at dopamine receptors, particularly D2 and D3 subtypes, thereby reducing dopamine activity in regions associated with psychotic disorders. Moreover, olanzapine displays antagonist activity at serotonin receptors, especially 5-HT2A, 5-HT2C, and 5-HT3 receptors, which contributes to its antipsychotic and mood-stabilizing properties. This mechanism helps regulate emotional responses and cognitive functions. Additionally, olanzapine's interaction with other receptors, including alpha-adrenergic, histaminergic, and muscarinic receptors, may contribute to its side effect profile. The modulation of these neurotransmitter systems collectively underlies olanzapine's effectiveness in managing psychotic disorders and certain mood disorders.

  • Ingredients

    Olanzapine
  • Drug Class

    Antipsychotic

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Olanzapine 5mg Capsule:

    • Used for managing symptoms of schizophrenia, helping patients stabilize their thoughts and behavior.
    • Used to treat acute manic episodes in bipolar disorder, providing rapid mood stabilization.
    • Used to prevent future manic or depressive episodes in bipolar maintenance treatment.
    • Used to control severe behavioral problems in children with autism, reducing aggression and irritability.
    • Used for managing severe nausea and vomiting when other treatments are ineffective.
    • Used as an adjunct therapy to manage severe depression when combined with antidepressants.
    • Used for short-term treatment of acute psychotic episodes, offering quick symptom relief.
    • Used to enhance the effectiveness of other medications in complex mental health cases.
  • In case of Overdose

    In the case of an overdose of Olanzapine 5mg Capsules, the severity of symptoms can vary. Excessive drowsiness, rapid heartbeat, and difficulty breathing may occur. Other potential effects include seizures, muscle stiffness, and loss of consciousness. Immediate medical intervention is essential to manage these symptoms and prevent potential complications. Promptly contacting emergency services or a healthcare professional is crucial when an overdose is suspected.

  • Missed Dose

    In the case of a missed dose of Olanzapine 5mg Capsule, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, it's important to discuss this with your healthcare provider to determine the best course of action and ensure the effectiveness of the medication.

  • How To Use

    To take Olanzapine 5mg Capsule, swallow the capsule whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions/situations when Olanzapine 5mg Capsule should not be taken:

    • Should not be given to individuals with a known hypersensitivity or allergy to Olanzapine or any other similar medications.
    • Not suitable for patients with a history of liver or kidney disease or impairment.
    • Contraindicated in individuals with a history of blood disorders or low white blood cell count.
    • Should not be used in patients with a history of seizures or epilepsy.
    • Not recommended for elderly patients with dementia, as it may increase the risk of death.
    • Should not be given to patients with a history of alcohol or substance abuse.
    • Contraindicated in individuals with a history of narrow-angle glaucoma.
    • Not suitable for individuals with a recent history of heart attack or unstable heart disease.
    • Should not be used in patients with a history of stroke or transient ischemic attack (TIA).
    • Avoid using in patients with severe depression or suicidal thoughts.
    • Contraindicated in patients with a condition called antipsychotic-induced neuroleptic malignant syndrome.
  • Side Effects

    The side effects of Olanzapine 5mg Capsule may include:

    • Drowsiness or sedation
    • Weight gain
    • Increased appetite
    • Dry mouth
    • Dizziness
    • Restlessness or akathisia (feeling of inner restlessness)
    • Constipation
    • Increased blood sugar levels
  • Precautions & Warnings

    Following are the precautions and warnings:

    • Olanzapine 5mg Capsule should be used with caution in elderly patients as they may be more sensitive to its effects, including the risk of stroke, confusion, and high blood sugar.
    • Patients with a history of seizures or conditions that lower the seizure threshold should be closely monitored, as olanzapine may lower the seizure threshold.
    • It may cause weight gain and changes in cholesterol and blood sugar levels, so regular monitoring of weight, blood sugar, and lipid profile is necessary.
    • Patients with a history of liver disease or alcohol abuse should be monitored for potential liver-related side effects.
    • Olanzapine may cause orthostatic hypotension, so caution is advised in patients with cardiovascular disease or conditions that could be negatively affected by low blood pressure.
    • It can increase the risk of developing diabetes, especially in patients with risk factors such as obesity or a family history of diabetes.
    • Patients and caregivers should be alert to the emergence of suicidal thoughts or behaviors, especially at the beginning of treatment or after dose changes.
  • Drug Interactions

    Following are the drug interactions for Olanzapine 5mg Capsule:

    • Alcohol and other central nervous system (CNS) depressants, such as opioids or benzodiazepines, can increase sedation and respiratory depression when used with olanzapine.
    • The effects of olanzapine may be decreased by strong CYP1A2 inducers like tobacco smoking, potentially requiring dose adjustments.
    • Combining olanzapine with other antipsychotic medications can increase the risk of extrapyramidal symptoms and other adverse effects.
    • Olanzapine may enhance the effects of certain antidepressants, especially tricyclic antidepressants, leading to increased side effects.
    • It can interact with medications that prolong the QT interval, such as certain antiarrhythmic drugs, increasing the risk of cardiac arrhythmias.
    • The effectiveness of anticonvulsant medications may be reduced by olanzapine, potentially lowering the seizure threshold.
    • Caution is advised when using olanzapine with medications that affect liver function, as it may impact the metabolism of both drugs.
  • Food Interactions

    Following are the food interactions for Olanzapine 5mg Capsule:

    • Alcohol consumption should be avoided as it can increase the sedative effects of Olanzapine, leading to enhanced drowsiness and dizziness.
    • Grapefruit and its juice should be consumed with caution as they may increase the blood levels of Olanzapine, potentially causing more side effects.
    • High-fat meals can slightly decrease the absorption of Olanzapine, so it is advisable to maintain a consistent diet pattern.
    • Caffeinated beverages like coffee or energy drinks might interfere with Olanzapine's calming effects, possibly increasing restlessness.
    • Avoid excessive salt intake as Olanzapine may cause water retention, leading to increased thirst and swelling.
    • Maintain a balanced diet, as Olanzapine can increase blood sugar and cholesterol levels, requiring regular monitoring.
    • Always follow healthcare provider's instructions regarding food and medication timing for optimal results.
    • Inform your doctor about any dietary changes or restrictions to ensure safe and effective medication use.
  • Storage/Disposal

    Olanzapine 5mg Capsules should be stored in a cool, dry area, ideally at room temperature between 68°F and 77°F (20°C and 25°C). Protect the capsules from light and moisture by keeping them in their original packaging or container. It's crucial to maintain the medication's integrity by not exposing it to excessive heat or cold. Always check the expiration date, and never use the capsules beyond this date. When disposing of unused or expired capsules, do not flush them or throw them into the trash. Instead, consult your pharmacist or local waste disposal company for safe disposal methods, ensuring they are kept out of the reach of children and pets to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Olanzapine 5mg Capsule:

    • Consult your doctor or pharmacist before use, especially if you have a medical history or are taking other medications.
    • Swallow the capsule whole with a full glass of water; do not crush, chew, or open it.
    • Take the capsule at the same time each day to maintain consistent blood levels.
    • Do not abruptly stop taking the medication; gradually reduce the dose as directed by your doctor.
    • Avoid alcohol consumption as it may intensify the medication's effects.
    • Inform your doctor if you experience any persistent side effects or allergic reactions.
    • Store the capsules in a cool, dry place, away from direct sunlight and moisture.

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