OMNIPAQUE 350MG 100ML INJ

Iohexol 350MG Injection is a non-ionic, water-soluble contrast medium used in medical imaging procedures. Its mechanism of action is based on its ability to temporarily alter the contrast of tissues and blood vessels during diagnostic imaging. When administered, Iohexol circulates in the bloodstream and distributes throughout the extracellular fluid. Its high iodine content effectively absorbs and attenuates X-rays, resulting in enhanced visualization of anatomical structures. Iohexol molecules do not interact significantly with biological tissues, allowing for clear and detailed imaging. The contrast enhancement provided by Iohexol aids in the detection and diagnosis of various medical conditions, particularly in procedures such as computed tomography (CT) scans and angiography.

Iohexol 350MG

Contrast media

Injection

The following are the uses of Iohexol 350MG Injection:

• Used for diagnostic purposes in computed tomography (CT) scans to visualize blood vessels and organs.
• Used for angiography to assess blood flow and detect vascular conditions.
• Used for determining the extent of tumors and planning radiation therapy.
• Used for evaluating kidney function and diagnosing kidney-related disorders.
• Used for myelography to examine the spinal cord and detect nerve compressions.
• Used for arthrography to visualize joints and diagnose joint-related issues.
• Used for urography to assess the urinary system and identify abnormalities.
• Used for contrast-enhanced ultrasound, aiding in the visualization of organs and blood vessels.

In the case of an overdose of Iohexol 350MG Injection, the severity of symptoms can vary. While mild cases may present with nausea and vomiting, more severe instances can lead to acute kidney injury and even renal failure. Other potential complications include allergic reactions, seizures, and cardiovascular issues. It is important to seek medical assistance promptly to address these risks and manage the symptoms effectively.

In the case of a missed dose of Iohexol 350MG Injection, it is important to consult your healthcare provider or radiologist promptly. They will guide you on whether to reschedule the procedure or adjust the dosage accordingly. Generally, missing a dose of this contrast agent is not a cause for concern, as it is typically administered under medical supervision. However, it is crucial to communicate any missed doses to ensure the accuracy and effectiveness of the diagnostic procedure.

To administer Iohexol 350MG Injection, prepare the injection by drawing the prescribed dose into a syringe, ensuring sterility, and inject it intravenously, following the recommended rate and dosage instructions provided by your healthcare professional.

Following are the conditions when Iohexol 350MG Injection should not be used:

• Must not be administered to individuals with a known allergy or hypersensitivity to Iohexol or any other similar contrast agents.
• Contraindicated in patients with severe renal impairment or kidney failure, as the medication is primarily eliminated through the kidneys.
• Not recommended for individuals with severe thyroid disorders, as it may affect thyroid function.
• Should not be used in patients with a history of severe cardiovascular diseases, including uncontrolled hypertension and recent myocardial infarction.
• Contraindicated in patients with pheochromocytoma, a rare tumor of the adrenal gland.
• Not suitable for individuals with a history of severe anaphylactic reactions to any substance.
• Must be avoided in patients with multiple myeloma, as it may affect bone marrow function.
• Should not be used in pregnant women unless the potential benefits outweigh the risks.
• Not recommended for breastfeeding mothers, as it is unknown if Iohexol passes into breast milk.

The side effects of Iohexol 350MG Injection may include:

• Allergic reactions, such as hives, itching, or difficulty breathing.
• Nausea and vomiting.
• Dizziness or lightheadedness.
• Headache.
• Skin rash or itching.
• Temporary hair loss.
• Mild diarrhea.
• A feeling of warmth or flushing.

Following are the precautions and warnings for Iohexol 350MG Injection:

• This medication should not be used in patients with a known allergy to Iohexol or any other ingredients in the injection.
• Patients with kidney disease or impairment should use this injection with caution, as it may affect kidney function.
• It is important to ensure adequate hydration before and after the procedure to minimize the risk of acute kidney injury.
• Diabetic patients should be monitored closely as Iohexol may cause temporary alterations in blood glucose levels.
• Patients with a history of thyroid disease should be monitored as this medication can affect thyroid function.
• Elderly individuals may be more susceptible to adverse effects, and dosage adjustments might be necessary.
• Iohexol may interact with other medications, including metformin and antithyroid drugs, so a comprehensive medical history should be reviewed.
• It is essential to inform your healthcare provider about all current medications and medical conditions before using this injection.

Following are the drug interactions for Iohexol 350MG Injection:

• Concurrent use with metformin may lead to lactic acidosis, particularly in patients with renal impairment.
• Iohexol may decrease the effectiveness of thyroid hormones, requiring adjustment of thyroid medication doses.
• Prolonged use with corticosteroids can increase the risk of hyperglycemia and fluid retention.
• Potassium-sparing diuretics may increase the risk of hyperkalemia when used with Iohexol.
• Antihypertensive medications might require dose adjustments as Iohexol can cause transient hypertension.
• Iohexol may enhance the nephrotoxic effects of aminoglycosides and certain antiviral drugs.
• Non-steroidal anti-inflammatory drugs (NSAIDs) could potentially increase the risk of renal toxicity when used in combination with Iohexol.

Following are the food interactions to be aware of with Iohexol 350MG Injection:

• It is generally recommended to fast for at least 4 hours before the procedure involving Iohexol injection to ensure accurate test results and minimize the risk of nausea.
• Avoid consuming foods high in iodine, such as seafood, seaweed, and iodized salt, for a few days before the procedure, as it can interfere with the accuracy of the test.
• Refrain from drinking coffee or other caffeinated beverages prior to the procedure, as caffeine can affect blood flow and potentially impact the diagnostic imaging.
• Ensure adequate hydration by drinking plenty of water before and after the procedure, unless instructed otherwise by your healthcare provider.
• Avoid consuming alcohol for at least 24 hours before and after the procedure, as it can affect kidney function and potentially impact the elimination of Iohexol.
• If you have any specific dietary restrictions or concerns, consult your healthcare provider for personalized advice regarding food interactions with Iohexol injection.
• Generally, maintaining a balanced diet and following any pre-procedure instructions provided by your healthcare team will help ensure the best outcomes with Iohexol 350MG Injection.

Iohexol 350MG Injection should be stored in a controlled environment, preferably in a cool and dry place at room temperature, ensuring it is protected from light and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the injection to extreme temperatures, such as those found near heat sources or in bathrooms, as this can impact its effectiveness. Always adhere to the expiration date indicated on the packaging, and when disposing of any unused or expired medication, do not flush or pour it down the drain. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods, ensuring that the medication is kept away from children to prevent accidental exposure or ingestion.

Following are the quick tips for Iohexol 350MG Injection:

• Iohexol is a contrast agent used for medical imaging procedures.
• Ensure you inform your doctor about any allergies or medical conditions before the procedure.
• It is administered by a healthcare professional, typically through an intravenous (IV) injection.
• During the injection, you may experience a warm sensation or a metallic taste.
• Stay well-hydrated before and after the procedure to help eliminate the contrast agent.
• Inform your doctor if you experience any unusual symptoms, such as itching, rash, or difficulty breathing.
• It is essential to follow the specific instructions provided by your healthcare team for the best imaging results.