Omsana (20mg) 14 Tablets

Olmesartan medoxomil is a prodrug that is converted to its active form, olmesartan, during absorption in the gastrointestinal tract. Once activated, olmesartan blocks the angiotensin II receptors, primarily subtype AT1. Angiotensin II is a potent vasoconstrictor, and by blocking its receptors, olmesartan prevents the binding of angiotensin II to these receptors. This inhibition leads to vasodilation, as the constrictive effects of angiotensin II are mitigated. As a result, blood pressure is reduced due to decreased peripheral resistance in blood vessels. Olmesartan selectively binds to the AT1 receptor, showing a much higher affinity for it than for the AT2 receptor, and this selective blockade contributes to its antihypertensive effect.

Angiotensin II receptor blocker

Tablet

The following are the uses of Olmesartan Medoxomil 20mg Tablet:

• Used for treating high blood pressure (hypertension).
• Used to lower and control blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.
• Used to improve blood flow and reduce the workload on the heart.
• Used in patients with diabetes and kidney problems to slow down the progression of kidney disease.
• Used to prevent cardiovascular events in patients with a history of heart disease.
• Used to manage hypertension in patients who have not responded well to other medications.
• Used as a long-term treatment option to maintain stable blood pressure levels.

The dosage is usually 10 mg orally once a day; may increase the dose to 20 mg in two weeks if further blood pressure reduction is needed.

In the case of an overdose of Olmesartan Medoxomil 20mg Tablets, it is important to seek medical advice promptly. Symptoms of an overdose may include severe dizziness, fainting, or a rapid or slow heartbeat. Do not induce vomiting or try home remedies; instead, contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the individual's condition and the amount ingested, ensuring appropriate medical care is administered.

In the case of a missed dose of Olmesartan Medoxomil 20mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you frequently miss doses, consider setting an alarm or using a pill organizer to help you stay on track with your medication regimen. It is crucial to maintain consistency in taking this medication as prescribed by your healthcare provider.

To take Olmesartan Medoxomil 20mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider, usually once daily with or without food.

Following are the conditions when Olmesartan Medoxomil 20mg Tablet should not be taken:

• Should not be used in patients with a known allergy to Olmesartan or any other angiotensin II receptor blockers (ARBs).
• Not suitable for individuals with a history of severe or chronic diarrhea or vomiting.
• Contraindicated in pregnant or breastfeeding women.
• Should not be used in patients with severe liver impairment or biliary obstruction.
• Not recommended for individuals with severe kidney disease or those on dialysis.
• Avoid in patients with a history of angioedema or swelling of the face, lips, throat, or tongue.
• Not suitable for children under 18 years of age.
• Should not be used in patients with bilateral renal artery stenosis.
• Contraindicated in patients with a condition called aortic stenosis (narrowing of the aortic valve in the heart).

The side effects of Olmesartan Medoxomil 20mg Tablet may include:

• Dizziness
• Headache
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea
• Muscle cramps
• Increased sensitivity to sunlight
• Skin rashes or itching

Following are the precautions and warnings for Olmesartan Medoxomil 20mg Tablet:

• Patients with a known allergy to Olmesartan or any other angiotensin receptor blocker (ARB) should not take this medication.
• Regular monitoring of kidney function is necessary, especially in patients with pre-existing kidney problems.
• Caution is advised for patients with a history of liver disease, as Olmesartan may affect liver function.
• Elderly patients may be more sensitive to the effects of this medication, so dosage adjustments might be required.
• Olmesartan can cause dizziness and lightheadedness, especially when standing up from a sitting or lying position; patients should exercise caution to avoid falls.
• It may cause fetal harm when used during pregnancy; pregnant women should consult their doctor before use.
• Breastfeeding women should seek medical advice as it is unclear if Olmesartan passes into breast milk.
• This medication may cause dehydration and electrolyte imbalances, especially in patients taking diuretics.

Following are the drug interactions for Olmesartan Medoxomil 20mg Tablet:

• Olmesartan can enhance the blood pressure-lowering effects of other antihypertensive medications, such as diuretics or beta-blockers, leading to excessive hypotension.
• NSAIDs (e.g., ibuprofen, naproxen) may reduce the antihypertensive effect of Olmesartan, potentially leading to decreased blood pressure control.
• When combined with potassium-sparing diuretics or potassium supplements, Olmesartan may cause an increase in serum potassium levels.
• The use of Olmesartan with angiotensin-converting enzyme (ACE) inhibitors may lead to increased serum potassium levels and a higher risk of renal impairment.
• Lithium levels may be increased when used concurrently with Olmesartan, requiring close monitoring of lithium concentrations.
• Rifampin, a strong CYP2C9 inducer, can decrease the effectiveness of Olmesartan by increasing its metabolism.
• Caution is advised when using Olmesartan with immunosuppressants, as it may increase the risk of infections and affect the therapeutic efficacy of these medications.

Following are the food interactions to consider with Olmesartan Medoxomil 20mg Tablet:

• Avoid excessive salt or sodium intake in your diet, as Olmesartan works to reduce blood pressure by reducing the effects of sodium.
• Limit the consumption of potassium-rich foods like bananas, oranges, and spinach if you have kidney problems, as Olmesartan can increase potassium levels.
• Alcohol may increase the blood pressure-lowering effect of Olmesartan, so moderation is advised.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Olmesartan, potentially increasing its levels in the blood.
• There is no specific food restriction with Olmesartan, but a balanced diet low in sodium and fat is generally recommended for blood pressure management.
• Avoid high-fat meals as they may reduce the absorption of Olmesartan, affecting its effectiveness.
• Consult your doctor or pharmacist for personalized advice on diet and medication adjustments to ensure the best treatment outcome.

Olmesartan Medoxomil 20mg Tablets should be stored in a secure and dry location, preferably in their original container, at room temperature (below 25°C/77°F). Protect the tablets from light and moisture by keeping the container tightly sealed. It is crucial not to expose the medication to excessive heat or cold, so avoid storing it in the bathroom, freezer, or car glove compartment. Always check the expiration date, and never use the tablets if they appear discolored, cracked, or show signs of degradation. For safe disposal, do not throw the tablets into the garbage or flush them down the toilet. Consult your pharmacist or local waste disposal company for guidance on how to safely dispose of unused or expired medication, ensuring it does not harm the environment. Keep the medication out of children's reach to prevent accidental ingestion.

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Following are the quick tips for Olmesartan Medoxomil 20mg Tablet:

• Consult your doctor for the correct dosage and duration tailored to your medical needs.
• Take the tablet by mouth, swallowing it whole without crushing or chewing.
• Consistency is key; aim to take your medication at the same time each day.
• Ensure you complete the full prescribed course, even if you feel better earlier.
• Avoid grapefruit juice while on this medication to prevent potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Regularly monitor your blood pressure and report any changes to your doctor.