Onamed (150mg) 1 Capsule

Fluconazole, an antifungal medication, interferes with the formation of the fungal cell membrane, a crucial structure that maintains the cell's integrity. It does this by blocking an enzyme called 14α-demethylase, which fungi needs to make an essential component of the cell membrane called ergosterol. By inhibiting this enzyme, Fluconazole prevents the synthesis of functional cell membranes, causing the fungus to leak and die.In addition to this primary mechanism, Fluconazole also inhibits the transformation of fungal cells from one form to another, disrupts the permeability of the fungal cell membrane, and inhibits certain enzyme reactions involved in fungal metabolism. These actions collectively prevent the growth and proliferation of fungi, effectively treating the fungal infections.

Azol Antifungal

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of fungal infections including Candida yeast infections of the skin, genital area, mouth, and esophagus (tube connecting the throat to the stomach).
• Treatment of fungal infections in patients with weak immune systems related to chemotherapy or radiation therapy.
• Treatment of coccidioidomycosis (valley fever) in patients who have a confirmed susceptibility to fluconazole.
• Treatment of infections caused by Cryptococcus neoformans. This type of fungus is most often seen in patients with weakened immune systems.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• The usual dose for yeast infection of the skin or nails is one 150-milligram tablet taken by mouth once a day for 2 weeks.
• The usual dose for yeast infection of the genitals is one 150-milligram tablet taken by mouth once a day for 7 days.
• For the prevention of yeast infections in those at high risk, the usual dose is one 150-milligram tablet taken by mouth once a week. Treatment should be continued until the risk of infection has passed.

Fluconazole is a medication that has been widely known to treat fungal infections. It is important to emphasize that one should seek immediate medical attention if an overdose is suspected. Some symptoms of overdose may include severe headaches, nausea, vomiting, and seizures. Overdose treatment may include supportive care and the use of specific medications to counteract the effects of the overdose along with treating the specific symptoms. It is prudent to emphasize that these treatment methods for overdose should be prescribed by licensed medical professionals who can conduct an in-person assessment.

It is paramount to adhere to the medication schedule prescribed by your physician for effective drug delivery and to avoid any complications. Fluconazole is a potent drug, and missing doses can lead to resistance, especially in treating systemic yeast infections.If you miss a dose of Fluconazole, take it as soon as possible. If it is close to the time for your next dose, skip the missed dose and adhere to your prescription schedule. Avoid taking a double dose to make up for the missed one, as it can lead to an overdose or drug interaction. For any further guidance, it is advisable to consult with your doctor or pharmacist. They may advise you based on your underlying condition and medical history, making it imperative to choose your source of advice on this matter wisely.

When taking Fluconazole 150mg, it's essential to follow your doctor or pharmacist's instructions carefully and thoroughly. Be sure to read the medication guide provided by the pharmacist before starting your treatment. If you have any questions, don't hesitate to ask your doctor or pharmacist. Take the Fluconazole 150mg tablets orally, typically once a day, with or without food. For the best results, take this medication at the same time each day. The length of your treatment depends on the type of fungal infection you are treating, so it's important to speak with your doctor to understand how long you will need to take this medication. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and follow your regular schedule. Do not take two doses at once to make up for a missed dose. Overall, it's important to follow your doctor's specific directions regarding your Fluconazole treatment and to communicate any questions or concerns you may have to them or your pharmacist.

Discerning instances where this medication may not be appropriate:

• You are allergic to fluconazole or any of the other ingredients in the tablet.
• You have serious liver disease or a history of it.
• You have or have had long-term or repeated infections with yeast ( Candida ).

Unraveling the side effects lurking behind this medications are as follows:

• Dizziness
• Nausea
• Vomiting
• Dry mouth
• Bitter taste
• Diarrhea
• Abdominal pain
• Fatigue
• Loss of appetite
• Metallic taste
• Suicidal thoughts
• Delayed onset of sexual arousal
• Erectile dysfunction
• Vaginal itching and discharge
• Liver damage
• Kidney damage
• Seizures
• High blood cholesterol
• Intestinal infection

The warnings and precautions associated with Fluconazole are:

• Patient with proarrhythmic condition (e.g., congenital or documented acquired QT prolongation, structural heart disease, sinus bradycardia, existing symptomatic arrhythmias, electrolyte disturbances [e.g., hypokalaemia, hypomagnesaemia, hypocalcaemia]), serious underlying disease (e.g., AIDS, cancer).
• Renal and hepatic impairment.
• Neonates and children.
• Pregnancy and lactation.

The drug interactions with fluconazole include:

• Warfarin – Fluconazole can enhance the effects of warfarin, increasing the risk of bleeding.
• CYP3A4 Substrates (e.g., midazolam, triazolam) – Fluconazole can increase the levels of drugs metabolized by CYP3A4, potentially leading to increased side effects.
• CYP2C19 Substrates (e.g., clopidogrel, omeprazole) – Fluconazole may increase the levels of drugs metabolized by CYP2C19.
• Phenytoin – Fluconazole can increase the levels of phenytoin, leading to potential toxicity.
• Theophylline – Fluconazole may increase the levels of theophylline, leading to toxicity.
• Rifampin – Rifampin may decrease the effectiveness of fluconazole by increasing its metabolism.
• Oral Hypoglycemics (e.g., sulfonylureas) – Fluconazole can enhance the hypoglycemic effects, increasing the risk of hypoglycemia.
• Statins (e.g., atorvastatin, simvastatin) – Fluconazole can increase statin levels, leading to an increased risk of myopathy.
• Benzodiazepines (e.g., diazepam) – Fluconazole can increase benzodiazepine levels, enhancing their effects.
• Antacids – Fluconazole absorption may be reduced when taken with antacids.

For Fluconazole, food interactions that should be considered are:

• Avoid consuming alcohol as it may increase the risk of stomach bleeding.
• Limit high-fat meals which can affect the absorption of the product.
• Taking the product with food may help reduce the risk of gastrointestinal discomfort.

Fluconazole 150mg tablets should be stored in their original container or packaging to protect them from light and moisture. They should be kept at room temperature, between 68°F and 77°F (20°C and 25°C). For optimum effectiveness, keep the medication away from sunlight, moisture, and humidity. Ensure the container is closed tightly after each use to prevent contamination or spillage. It is recommended to consult a medical professional if you have specific queries about storing Fluconazole 150mg tablets. Storing Fluconazole tablets as advised by healthcare professionals will ensure the medication's potency and effectiveness, optimizing its efficacy in treating yeast infections in both women and men.

Lab tests are not required when taking Fluconazole 150mg; however, it is important to be open and honest with your healthcare provider about your medical history and current condition. This is because allergies and pre-existing medical conditions can affect how this antifungal medication behaves in the body. While taking this medication, it is possible to experience some side effects. These may include nausea, vomiting, diarrhea, stomach pain, headache, and dizziness. If these side effects occur and persist or worsen, it is crucial to consult with a doctor or pharmacist to determine if adjustments are needed in your treatment plan. Since this medication can cause harm to a fetus, it is important to let your doctor know if you are pregnant or planning to become pregnant. Additionally, this medication can interact with other drugs, so it is crucial to provide your doctor with a complete list of medications you are taking to avoid any harmful drug interactions. Although regular blood tests and liver function tests are not mandatory, they can help monitor your body's response to the medication. These tests can ensure the medication is not causing any harmful effects, and your doctor can use the results to adjust the dosage or stop the treatment if needed. Overall, it is essential to closely monitor your condition and symptoms while taking Fluconazole 150mg. Promptly consulting with your healthcare provider if you experience any changes in your health or if the symptoms of the fungal infection do not improve or worsen during treatment is crucial.