onbrez (300mcg) 30 Capsules

Indacaterol, a medication found in 300mcg capsules, is a long-acting beta-2 adrenergic receptor agonist (LABA). Its mechanism of action primarily involves stimulating beta-2 adrenergic receptors in the lungs, which leads to smooth muscle relaxation in the airways. This relaxation results in bronchodilation, making it easier for air to flow in and out of the lungs. By activating these receptors, indacaterol triggers a cascade of intracellular events, primarily involving the elevation of cyclic adenosine monophosphate (cAMP) levels. This increase in cAMP subsequently inhibits the release of mediators that cause bronchoconstriction, thereby promoting sustained dilation of the airways and improving breathing in patients with respiratory conditions like chronic obstructive pulmonary disease (COPD). The selective action of indacaterol on beta-2 receptors contributes to its effectiveness in managing respiratory disorders.

Indacaterol 300mcg

Long-acting beta-2 agonist.

capsule

The following are the uses of Indacaterol 300mcg Capsule:

• Used for long-term management of chronic obstructive pulmonary disease (COPD)
• Used to improve breathing and reduce flare-ups
• Used to relax and open airways, making breathing easier
• Used to reduce coughing and shortness of breath
• Used as a once-daily maintenance treatment for better control of symptoms
• Used to enhance exercise tolerance and overall lung function
• Used to prevent airway spasms and inflammation
• Used to promote better quality of life for COPD patients

In the case of an overdose of Indacaterol 300mcg Capsules, it is important to recognize the potential symptoms and seek medical advice promptly. Overdose may lead to an exacerbation of typical side effects, including tremors, headache, and muscle cramps. In more severe cases, an overdose can result in an irregular heartbeat, palpitations, and severe nausea. If an overdose is suspected, immediate medical care should be sought, and the patient should be monitored for any adverse reactions.

In the case of a missed dose of Indacaterol 300mcg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. It is always best to consult your healthcare provider if you have any concerns or questions regarding missed doses.

To use Indacaterol 300mcg capsules, simply remove one capsule from the blister pack and inhale the contents using the provided inhaler device, ensuring the medicine reaches your lungs by breathing in slowly and deeply after inserting the capsule into the inhaler.

Following are the conditions/situations when Indacaterol 300mcg Capsule should not be used:

• Should not be used in individuals with a known allergy to Indacaterol or any of the excipients in the formulation.
• Not suitable for individuals with a history of severe allergic reactions to milk proteins, as the capsule contains lactose.
• Contraindicated in patients with asthma, as it is not indicated for the treatment of acute asthma symptoms.
• Should not be used during an asthma attack as rescue medication.
• Not recommended for individuals with severe heart problems or uncontrolled high blood pressure.
• Should be avoided in patients with severe liver impairment.
• Not suitable for children and adolescents under 18 years of age, as the safety and efficacy have not been established in this age group.
• Should not be used as a substitute for corticosteroids in asthma management.

The side effects of Indacaterol 300mcg Capsule may include:

• Headache
• Dizziness
• Tremor
• Cough
• Throat irritation
• Chest pain
• Palpitations
• Muscle cramps

Following are the precautions and warnings for Indacaterol 300mcg Capsule:

• This medication is intended for inhalation use only and should not be swallowed.
• Patients with a history of respiratory issues, such as asthma or chronic obstructive pulmonary disease (COPD), should use Indacaterol with caution, as it may not be suitable for all cases.
• Indacaterol may cause paradoxical bronchospasm; if this occurs, patients should stop using it immediately and seek medical attention.
• Patients with cardiovascular problems, including heart rhythm disorders or hypertension, should be closely monitored while using Indacaterol.
• It may cause tremors and increased heart rate; if these symptoms become severe, consult a healthcare professional.
• Pregnant and breastfeeding women should only use Indacaterol if the potential benefits outweigh the risks, and under the guidance of a healthcare provider.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.
• Always read the patient information leaflet provided with the medication for detailed precautions and instructions.

Following are the drug interactions for Indacaterol 300mcg Capsule:

• Indacaterol may interact with other beta-2 agonists, as combined use may increase the risk of cardiovascular effects, including increased heart rate and blood pressure.
• Concomitant use with other long-acting beta-agonists (LABAs) is not recommended due to potential additive side effects.
• The effect of indacaterol may be reduced by beta-blockers, and caution is advised when using them together.
• Indacaterol can interact with diuretics, especially potassium-depleting diuretics, potentially leading to electrolyte imbalances.
• It may also interact with other sympathomimetic drugs, such as epinephrine, causing an excessive stimulatory effect.
• Caution is advised when using indacaterol with monoamine oxidase inhibitors (MAOIs), as it may increase the risk of hypertensive crisis.
• The use of indacaterol with other anticholinergic medications should be monitored due to potential additive effects on the cardiovascular system.
• Indacaterol may increase the risk of hypokalemia when used with corticosteroids, requiring regular monitoring of potassium levels.

Following are the food interactions for Indacaterol 300mcg Capsule:

• Avoid consuming grapefruit or grapefruit juice as it can increase the concentration of Indacaterol in the blood, potentially leading to an increased risk of side effects.
• Alcohol consumption should be limited as it may cause excessive relaxation of airway muscles, exacerbating breathing difficulties.
• Caffeine-rich foods and beverages might interfere with the medication's effectiveness, so monitor your intake.
• Foods high in vitamin K, like leafy greens, can potentially affect blood clotting when taken with Indacaterol.
• Avoid high-fat meals as they may decrease the absorption of Indacaterol, reducing its effectiveness.
• Salt and salty foods should be consumed in moderation as Indacaterol can cause an increase in blood pressure.
• Consult your healthcare provider about any specific dietary restrictions or recommendations while using this medication.
• Always follow the dosage instructions provided by your doctor or pharmacist.

Indacaterol 300mcg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the capsules in their original packaging, tightly sealed to maintain their integrity. It is crucial not to expose the medication to excessive heat or cold, so avoid storing it near ovens or refrigerators. Regularly check the expiration date, and dispose of any expired capsules promptly. For proper disposal, consult your pharmacist or healthcare provider for guidance, and never flush medications down the toilet or sink. Keep the capsules out of children's reach to prevent accidental consumption.

Following are the quick tips for Indacaterol 300mcg Capsule:

• Take the capsule as directed by your doctor, usually once daily.
• Swallow the capsule whole with a glass of water, do not crush or chew.
• Take it at the same time each day to maintain consistent levels.
• Ensure you have a full lung function test before starting this medication.
• Inform your doctor if you have any lung or breathing problems.
• Do not stop taking the capsule without consulting your healthcare provider.
• Store the capsules in a cool, dry place, away from direct sunlight.