Opticon-A (0.025/0.3%) 15ml Eye Drops

Naphazoline acts as an alpha-adrenergic agonist, primarily targeting the alpha-1 adrenergic receptors in the blood vessels of the eye. It stimulates these receptors, leading to vasoconstriction, which reduces redness and inflammation by narrowing the blood vessels on the eye's surface. Pheniramine maleate, on the other hand, is an antihistamine that blocks the H1 histamine receptors. This action helps to alleviate itching and allergic conjunctivitis symptoms by preventing the effects of histamine, a chemical released during allergic reactions.

Sympathomimetic

Pheniramine:

Drop

1

In the case of an overdose of Naphazoline and Pheniramine Maleate 0.30% Drops, individuals may experience symptoms such as increased drowsiness, dizziness, and dry mouth. If a significant amount is ingested, it can lead to more severe effects like rapid heartbeat, difficulty breathing, and confusion. Prompt action is necessary; contact a healthcare professional or poison control center for guidance on managing the overdose and ensuring appropriate medical care.

In the case of a missed dose of Naphazoline, Pheniramine Maleate 0.30% Drops, administer the missed dose as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice on how to resume your medication regimen safely. It's important to maintain consistency with this medication for optimal relief.

To use Naphazoline, Pheniramine Maleate 0.30% Drops, gently tilt your head back, instill the prescribed number of drops into the affected eye(s) while pulling down the lower eyelid, and maintain a closed eye for a few minutes to ensure proper absorption.

Following are the conditions/situations when Naphazoline and Pheniramine Maleate 0.30% Eye Drops should not be used:

• Avoid using if you have a known allergy or hypersensitivity to Naphazoline, Pheniramine Maleate, or any other ingredients in the eye drops.
• Not suitable for individuals with narrow-angle glaucoma or those at risk of developing narrow-angle glaucoma.
• Should not be used in patients with severe cardiovascular diseases, including hypertension, coronary artery disease, or heart rhythm disorders.
• Contraindicated in individuals who have undergone certain eye surgeries, such as cataract removal with intraocular lens implantation.
• Not recommended for children below a certain age (consult a pediatrician for age-specific guidelines).
• Avoid using if you have a history of respiratory or pulmonary diseases, such as asthma or chronic obstructive pulmonary disease (COPD).
• Do not use if you have a history of difficulty urinating or urinary retention.
• Should not be used if you are currently taking monoamine oxidase inhibitors (MAOIs) or have taken them within the past 14 days.

The side effects of Naphazoline, Pheniramine Maleate 0.30% Drops may include:

• Increased heart rate
• Dizziness or drowsiness
• Dry mouth and throat
• Burning or stinging sensation in the eyes
• Blurred vision or temporary reduced vision clarity
• Itchy or watery eyes
• Increased sensitivity to light

Following are the precautions and warnings for Naphazoline, Pheniramine Maleate 0.30% Drops:

• Do not use this medication if you have narrow-angle glaucoma or untreated wide-angle glaucoma.
• Avoid using if you have a history of heart disease, high blood pressure, or thyroid problems without consulting a healthcare professional.
• If you are using any other eye drops or have a pre-existing eye condition, inform your doctor before using these drops.
• These drops may cause temporary blurred vision; avoid driving or operating machinery until your vision is clear.
• Prolonged or excessive use may lead to rebound congestion or nasal irritation; use only as directed.
• Children under 6 years of age should not use this medication unless prescribed by a doctor.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before using these drops.

Following are the drug interactions for Naphazoline, Pheniramine Maleate 0.30% Drops:

• Naphazoline may interact with other alpha-adrenergic agonists, leading to increased cardiovascular effects and blood pressure.
• Pheniramine can add to the sedative effects of alcohol, antidepressants, or other CNS depressants.
• Drugs that affect the liver's CYP450 enzyme system, such as certain antifungals or antibiotics, may alter the metabolism of Pheniramine.
• Antihistamines like Pheniramine may reduce the effectiveness of bronchodilators used in asthma treatment.
• Concomitant use with other anticholinergic medications can increase the risk of side effects such as dry mouth, blurred vision, and urinary retention.
• Naphazoline may interact with beta-blockers, causing an increase in blood pressure.
• It can also interact with monoamine oxidase inhibitors (MAOIs), potentially leading to a hypertensive crisis.
• Use with caution in patients taking anticholinesterase agents, as it may reduce the therapeutic effect of these medications.

Following are the food interactions for Naphazoline, Pheniramine Maleate 0.30% Eye Drops:

• Avoid consuming alcohol during the use of these eye drops, as it may increase the risk of drowsiness and dizziness, impacting your ability to see clearly.
• Grapefruit and its juice should be consumed with caution as they may affect the metabolism of the medication, potentially leading to increased side effects.
• Caffeine-rich foods and beverages, such as coffee, tea, and energy drinks, should be limited as they may counteract the sedative effects of Pheniramine Maleate, reducing its effectiveness in alleviating allergy symptoms.
• Foods high in sodium (salt) might lead to increased fluid retention, which could be problematic for individuals with certain health conditions. It's advisable to monitor salt intake while using Naphazoline.
• It is generally advisable to maintain a balanced diet, ensuring adequate hydration, and consuming a variety of fruits, vegetables, and whole grains to support overall health and potentially reduce allergy symptoms.
• There are no specific food restrictions with Naphazoline, but it's essential to follow a healthy diet to maintain overall well-being.
• Always consult your healthcare provider or pharmacist for personalized advice regarding food interactions, especially if you have underlying health conditions.
• Stay well-hydrated, as this can help maintain eye health and comfort during the use of eye drops.

Naphazoline, Pheniramine Maleate 0.30% Eye Drops should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be retained, keeping the bottle tightly sealed to maintain its integrity and prevent contamination. Avoid exposing the eye drops to extreme temperatures, such as storing them in the refrigerator, freezer, or near heating devices, as this can impact their effectiveness. Always check the expiration date, and if the drops are past their expiry, do not use them and dispose of them responsibly. Proper disposal methods should be followed, avoiding flushing or pouring them down the drain; instead, seek guidance from a pharmacist or healthcare professional for safe disposal practices. Keep the medication securely stored away from children to prevent accidental exposure.

Following are the quick tips for Naphazoline, Pheniramine Maleate 0.30% Drop:

• Wash your hands before using the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few seconds to minimize drug absorption into the bloodstream.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• If you are using other eye medications, wait at least 5-10 minutes before applying the next medication.
• Do not wear contact lenses while using these eye drops unless your doctor advises otherwise.
• Store the eye drops at room temperature, away from direct sunlight and moisture.