Orglu (80/80mg) 30 Tablets

Orglu (80/80mg) 30 Tablets

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  • Manufacturer SAMI Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Phloroglucinol, trimethylphloroglucinol

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Phloroglucinol is a chemical compound that possesses antioxidant and anti-inflammatory properties. This is achieved by inhibiting the activity of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are enzymes that play a role in inflammation. By blocking these enzymes, phloroglucinol can reduce the production of inflammatory compounds. Trimethylphloroglucinol is a derivative of phloroglucinol. It contains additional methyl groups and has been shown to have antioxidant and antibacterial properties. Although research is ongoing, it is thought that trimethylphloroglucinol contributes to the overall beneficial effects of phloroglucinol-containing plants and compounds. Both phloroglucinol and trimethylphloroglucinol are believed to play a role in the therapeutic effects of traditional medicinal plants. Their potential usage in modern medicine and pharmaceutical applications is an ongoing area of research.

  • Ingredients

    Phloroglucinol, trimethylphloroglucinol
  • Drug Class

    Non Atropinic Antispasmodic Agent

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Skin whitening agent
    • Treatment for certain skin diseases
    • Used in permanent wave formulations for hair
    • Used in making sunscreen formulations
    • Antioxidant effect
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For treating nausea and vomiting, the recommended dose of Phloroglucinol is 80-100mg
    • For treating heartburn and reflux esophagitis (inflammation of the esophagus), the recommended dose of Trimethylphloroglucinol is 80-160mg
    • These doses should be taken every 6 hours, but do not take more than 400mg in a day
    • Always make sure to read and follow the instructions on the label before using any medication.
  • In case of Overdose

    Overdose of phloroglucinol and trimethylphloroglucinol may cause low blood pressure, tightening of airways, and gastrointestinal irritation such as nausea and vomiting. These symptoms require immediate medical attention and would require treatment of the symptoms as they occur. This treatment may involve increasing blood pressure, relief of breathing difficulties, and anti-emetics (anti-nausea medications) for the nausea and vomiting. It is highly recommended that you call your local emergency number or proceed to the emergency room immediately to closely monitor your condition and progress.

  • Missed Dose

    If you have missed a dose of phloroglucinol 80mg and trimethylphloroglucinol 80mg, it is important to take the missed dose as soon as possible. However, if it is almost time for your next scheduled dose, you should skip the missed dose and focus on taking the next dose at the scheduled time. This is to ensure that you do not take too much of the medication, which may lead to overdose and other health complications. If you are uncertain about the next steps after missing a dose, it is best to consult with a medical professional for more tailored advice. They can provide you with appropriate guidance on how to proceed, ensuring that you are still following the prescribed treatment plan.

  • How To Use

    Before taking Phloroglucinol 80mg and Trimethylphloroglucinol 80mg, it is crucial to read the medication guide provided by your pharmacist. This guide will give you detailed instructions on how to take the medication both orally and topically. It is important to follow the provided instructions carefully and consult your doctor or pharmacist with any questions.For oral use, the recommended dosage is 80mg (one tablet) taken every eight hours. However, do not take more than 320mg (four tablets) per day. It is best to take the tablet with a large glass of water, and preferably with food, to prevent an upset stomach. For topical use, the dosage and exact instructions must be followed carefully as written on the medication label. Ensure you consult with your physician or pharmacist to understand the correct method of use. It is important to note that you should not take this medication if you have any pre-existing medical conditions, are currently taking any prescription drugs, or if you are pregnant or lactating, unless otherwise advised by your physician. This medication may cause drowsiness or dizziness, so it is advised to avoid operating heavy machinery, driving, or consuming alcohol while taking it. If you experience any adverse reactions, stop using the medication and consult a medical professional immediately. Finally, it is crucial to follow the recommended dosage and complete the full course of treatment, even if you feel better. If you have any further questions or concerns about using this medication, consult a medical professional for guidance.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Hypersensitivity
    • Liver or kidney impairment
    • Pregnancy and breastfeeding
    • Child
    • Active peptic ulcer
    • Anemia, malnutrition, or bleeding problems
    • Interactions with other drugs
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Nausea
    • Vomiting
    • Diarrhea
    • Loss of appetite
    • Yellowing of the eyes and skin
    • Headache
    • Rapid heart rate
    • Weakness
    • Severe abdominal pain
    • Jaundice
  • Precautions & Warnings

    The warnings and precautions associated with Phloroglucinol and Trimethylphloroglucinol are:

    • Patient with history of allergic reactions to any of the drug components.
    • Use with caution in patients with severe hepatic or renal impairment.
    • Avoid use in patients with galactose intolerance, lactase deficiency, or glucose-galactose malabsorption.
    • Not recommended for use in children below 2 years of age.
    • Patients with history of gastrointestinal disorders (e.g., ulcer, gastrointestinal bleeding).
    • Use with caution in elderly patients.
    • Pregnancy and lactation—consult with a healthcare professional before use.
    • Avoid in patients with a history of seizures or seizure disorders.
    • Do not exceed recommended dosage to avoid potential side effects.
    • Monitor for any signs of hypersensitivity reactions during initial administration.
  • Drug Interactions

    The drug interactions with phloroglucinol and trimethylphloroglucinol include:

    • Other Spasmolytics – May enhance effects.
  • Food Interactions

    For Phloroglucinol and Trimethylphloroglucinol, food interactions that should be considered are:

    • No significant interactions with food.
    • Taking with food may help enhance absorption.
  • Storage/Disposal

    Phloroglucinol and trimethylphloroglucinol are two distinct compounds with different molecular structures and properties. Phloroglucinol has a molecular formula of C6H3(OH)3 and a molecular weight of 161.13 g/mol. It is a white crystalline solid with a boiling point of 285°C and a melting point of 61°C. Phloroglucinol is soluble in alcohol, ether, and chloroform but insoluble in water. It is used in manufacturing perfumes, pharmaceuticals, and other organic compounds. Trimethylphloroglucinol has a molecular formula of C6H3(OH)(OCH3)3 and a molecular weight of 191.22 g/mol. It is a volatile, aromatic compound with a boiling point of 264°C and a melting point of 96°C. Like phloroglucinol, trimethylphloroglucinol is soluble in alcohol, ether, and chloroform but insoluble in water. It has a pleasant odor and is used in the production of perfumes, agrochemicals, and pharmaceuticals. These compounds should be stored in a cool, dry, well-ventilated place to keep them away from heat and open flames. When handling these compounds, it is essential to wear proper protective gear to prevent exposure. They should be stored in closed containers in a locked cabinet or pantry, away from children and pets. To prevent dangerous reactions, do not mix or store them with incompatible substances, such as strong acids or bases. It is further recommended to consult the material safety data sheet for each compound for specific storage instructions and guidelines.

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