Oribro DS (200mg) 10 Tablets

Cefpodoxime 200mg tablets, a third-generation cephalosporin antibiotic, exert their antibacterial effect by inhibiting the synthesis of the bacterial cell wall. The primary target of cefpodoxime is the penicillin-binding proteins (PBPs), which are essential for cross-linking the peptidoglycan chains in the bacterial cell wall. By binding to these PBPs, cefpodoxime disrupts the final stages of cell wall synthesis, leading to the weakening and eventual lysis of the bacterial cell. This mechanism of action is selective for bacterial cells, as human cells do not have a cell wall structure. Cefpodoxime is particularly effective against a wide range of Gram-positive and Gram-negative bacteria, including common pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, and Escherichia coli.

Cefpodoxime 200mg

Cephalosporin antibiotic.

Tablet

The following are the uses of Cefpodoxime 200mg Tablet:

• Used for treating bacterial infections, such as those affecting the lungs, throat, and urinary tract.
• Used for managing acute bacterial exacerbations in patients with chronic bronchitis.
• Used for treating skin and soft tissue infections caused by susceptible bacteria.
• Used for controlling the progression of bacterial infections, preventing their spread.
• Used for alleviating symptoms like fever, inflammation, and pain associated with bacterial infections.
• Used for improving patient outcomes by eliminating or reducing the presence of harmful bacteria.
• Used for ensuring a prompt and effective response to bacterial infections when prescribed.

Follow these dosage instructions:

• Adults and Adolescents Dosage (12 years and older)

Take the tablet or oral suspension as per the doctor's recommendation. The daily recommended dosage is 200mg to 400mg. Only in case of skin infections, the dosage can be taken up to 800mg.

• Infants and Pediatric Dosage (Ages 2 months through 12 years)

For the pediatric population, the daily recommended dosage is 10mg.

In the case of an overdose of Cefpodoxime 200mg Tablets, it is important to recognize the potential risks and take prompt action. Symptoms of an overdose may include nausea, vomiting, diarrhea, and abdominal pain. If you suspect an overdose, contact a healthcare professional immediately. They can provide guidance and support to manage any adverse effects and ensure appropriate medical care. Prompt medical intervention can help minimize the impact of an overdose and ensure the well-being of the individual.

In the case of a missed dose of Cefpodoxime 200mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It is generally recommended to avoid doubling the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may advise you to restart the medication or provide alternative instructions.

To take Cefpodoxime 200mg Tablet, swallow the tablet whole with a full glass of water, ensuring you follow the prescribed dosage as directed by your healthcare provider, typically taken once or twice a day, either with or without food, depending on your specific instructions.

Here are the situations when Cefpodoxime 200mg Tablet should not be used:

• Avoid using this medication if you have a known allergy to Cefpodoxime or any other cephalosporin antibiotics.
• Do not take this medicine if you have a history of severe allergic reactions to penicillin.
• Contraindicated in patients with a history of colitis or other severe gastrointestinal disorders.
• Should not be used if you have a history of seizures or other neurological disorders.
• Not recommended for individuals with severe kidney disease or on dialysis.
• Avoid using this medication if you have a history of stomach surgery or intestinal conditions.
• Do not administer to infants below 3 months of age.

The side effects of Cefpodoxime 200mg Tablet may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain
• Headache
• Dizziness
• Skin rash or itching
• Vaginal yeast infection
• Fatigue

Following are the precautions and warnings for Cefpodoxime 200mg Tablet:

• Not recommended for individuals with a known allergy to Cefpodoxime or other cephalosporin antibiotics.
• Should be used with caution in patients with a history of kidney or liver disease, as dosage adjustments may be necessary.
• Cefpodoxime may cause diarrhea, and if it becomes severe or persistent, patients should seek medical attention as it could indicate a more serious condition.
• Patients with a history of gastrointestinal problems should inform their doctor before taking this medication.
• This medication may reduce the effectiveness of certain contraceptive methods, so alternative birth control methods are advised.
• Elderly patients may be more susceptible to side effects, and their kidney function should be monitored during treatment.
• Cefpodoxime may cause false positive results in certain glucose urine tests, so alternative testing methods should be considered.

Following are the drug interactions for Cefpodoxime 200mg Tablet:

• Probenecid can decrease the excretion of Cefpodoxime, potentially increasing its levels in the body.
• Nephrotoxic drugs like aminoglycosides may increase the risk of kidney damage when used with Cefpodoxime.
• Concomitant use with other antibiotics like metronidazole may lead to an altered gut flora and potential antibiotic resistance.
• Cefpodoxime may reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Antacids containing aluminum or magnesium can decrease the absorption of Cefpodoxime if taken simultaneously.
• Drugs that affect renal function, such as diuretics, may influence the elimination of Cefpodoxime.
• The risk of bleeding may increase when combined with anticoagulants or antiplatelet drugs.

Following are the food interactions for Cefpodoxime 200mg Tablet:

• Avoid consuming alcohol during the treatment with Cefpodoxime as it may increase the risk of side effects like stomach upset and dizziness.
• Grapefruit and grapefruit juice consumption should be avoided as it can interfere with the absorption of Cefpodoxime, leading to reduced effectiveness.
• Dairy products like milk, cheese, and yogurt may decrease the absorption of Cefpodoxime; consider separating these foods from medication by a few hours.
• High-fat meals may delay the absorption of Cefpodoxime, so it is best to take the medication on an empty stomach or with a light meal.
• Caffeinated beverages may increase the elimination of Cefpodoxime, so limit coffee, tea, or energy drinks while on this medication.
• Avoid iron-rich foods like red meat, spinach, and iron-fortified cereals as they can decrease the absorption of Cefpodoxime. Take the medication a few hours before or after consuming these foods.
• Vitamin and mineral supplements, especially those containing calcium, iron, and zinc, can interfere with Cefpodoxime absorption. Take supplements at a different time than the medication.
• Consult your healthcare provider if you have a specific diet or food preferences to ensure the medication's effectiveness.

Cefpodoxime 200mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in bathrooms or near heat-emitting appliances. Always adhere to the expiration date indicated on the packaging, and when the medication is no longer needed or has expired, do not flush or pour it down the drain. Contact your pharmacist or healthcare provider for guidance on proper disposal methods to ensure environmental safety. Keep the medication away from children to prevent accidental consumption.

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Following are the quick tips for Cefpodoxime 200mg Tablet:

• Always take the tablet as directed by your doctor, typically twice a day.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Take the medicine at evenly spaced intervals to maintain an effective level in the body.
• You can take it with or without food, but if stomach upset occurs, take it with food.
• Complete the full course of medication as prescribed, even if you feel better earlier.
• Store the tablets at room temperature, away from moisture and direct sunlight.
• If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.