Orion DIU (20/12.5mg) 10 Tablets

Olmesartan medoxomil, the active ingredient in the 5mg tablet, acts as a selective antagonist of the angiotensin II receptor type 1 (AT1). This mechanism of action is crucial in blocking the effects of angiotensin II, a potent vasoconstrictor hormone. By specifically targeting the AT1 receptors, olmesartan medoxomil effectively inhibits the binding of angiotensin II, leading to vasodilation and a subsequent reduction in blood pressure. This process helps to lower blood pressure by relaxing the blood vessels, allowing for improved blood flow and reduced cardiovascular strain.

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Olmesartan Medoxomil 5mg Tablet:

• Used for treating high blood pressure (hypertension) in adults and children over 6 years old.
• Used to lower blood pressure, reducing strain on the heart and arteries.
• Used to prevent cardiovascular events, such as heart attacks and strokes, in high-risk patients.
• Used to slow the progression of kidney disease in patients with hypertension and diabetes.
• Used to improve blood flow and reduce the risk of vascular complications.
• Used as a long-term treatment to maintain consistent blood pressure control.
• Used as an alternative for patients who experience side effects with other blood pressure medications.

In the case of an overdose of Olmesartan Medoxomil 5mg Tablets, it is important to recognize the signs and act swiftly. Common symptoms may include dizziness, a rapid or slow heartbeat, and lightheadedness. If you suspect an overdose, contact a healthcare professional or poison control center immediately. They will provide guidance on the necessary steps to take, which may include inducing vomiting or administering activated charcoal to prevent further absorption.

In the case of a missed dose of Olmesartan Medoxomil 5mg Tablet, it is important to take the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is generally recommended to take the missed dose within 12 hours of the scheduled time; if more than 12 hours have passed, wait and take the next scheduled dose. Always consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Olmesartan Medoxomil 5mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Following are the conditions when Olmesartan Medoxomil 5mg Tablet should not be taken:

• Avoid if you have a known allergy or hypersensitivity to Olmesartan Medoxomil or any other angiotensin II receptor blockers (ARBs).
• Not suitable for individuals with a history of severe gastrointestinal problems or intestinal narrowing.
• Should not be used during pregnancy, especially in the second and third trimesters.
• Contraindicated in individuals with severe liver impairment or biliary obstruction.
• Do not use if you have a condition called hereditary angioedema.
• Not recommended for children under 1 year of age due to potential safety concerns.
• Avoid if you have diabetes and are taking a medication called aliskiren.

The side effects of Olmesartan Medoxomil 5mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea
• Headache
• Muscle cramps or joint pain
• Increased sensitivity to sunlight
• Skin rashes or itching

Following are the precautions and warnings for Olmesartan Medoxomil 5mg Tablet:

• Patients with a known allergy to Olmesartan Medoxomil or any other angiotensin receptor blocker (ARB) should not take this medication.
• Blood pressure should be monitored regularly while taking this medication, especially in patients with kidney disease or impaired liver function.
• It may cause dizziness or lightheadedness, so caution is advised when performing tasks that require alertness.
• Elderly patients may be more sensitive to the effects of this medication, and dosage adjustments might be necessary.
• Not recommended for use during pregnancy, especially in the second and third trimesters, as it may cause harm to the fetus.
• Breastfeeding women should consult their doctor as it may pass into breast milk.
• Patients with a history of angioedema should use this medication with caution, as it may increase the risk of this condition.
• Discontinuing the medication without consulting a doctor is not recommended, as it may lead to a rapid rise in blood pressure.

Following are the drug interactions for Olmesartan Medoxomil 5mg Tablet:

• NSAIDs (e.g., ibuprofen) may decrease the antihypertensive effect of Olmesartan.
• Olmesartan can increase serum lithium levels when used with lithium.
• Thiazide diuretics, when used with Olmesartan, may increase the risk of renal dysfunction.
• The antihypertensive effect of Olmesartan may be reduced by non-steroidal anti-inflammatory drugs (NSAIDs) including selective COX-2 inhibitors.
• Potassium-sparing diuretics, when combined with Olmesartan, may lead to hyperkalemia.
• When used with other antihypertensives, Olmesartan may cause additive hypotension.
• Olmesartan may enhance the hypoglycemic effects of insulin or oral antidiabetic agents.

Following are the food interactions to consider with Olmesartan Medoxomil 5mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they can increase the blood levels of Olmesartan, potentially leading to an increased risk of side effects like low blood pressure and dizziness.
• Avoid excessive alcohol consumption as it may enhance the blood pressure-lowering effect of Olmesartan, which could result in dizziness or lightheadedness.
• High-salt foods should be limited as Olmesartan works to reduce blood pressure by reducing the effects of salt on the body.
• Potassium-rich foods like bananas, oranges, and spinach can be beneficial, but excessive intake may lead to high potassium levels in the blood.
• Maintain a balanced diet as Olmesartan may cause mild increases in potassium and creatinine levels.
• No significant food interactions directly impact the absorption of Olmesartan, but it's advisable to take the medication with a glass of water, as instructed by your doctor.
• Always follow the dietary advice provided by your healthcare professional to ensure the medication's effectiveness and minimize potential side effects.

Olmesartan Medoxomil 5mg Tablets should be stored in a secure and dry location, preferably in their original container, at room temperature (68°F to 77°F) with brief excursions permitted between 59°F and 86°F. Protect the tablets from excessive heat, moisture, and direct sunlight, and keep them away from children and pets. Ensure the container is tightly closed after each use to maintain its integrity and prevent contamination. Do not use the tablets if the packaging is damaged or shows signs of tampering. When disposing of unused or expired medication, do not flush or pour it into the drainage system; instead, follow local guidelines or consult a pharmacist for safe disposal methods to protect the environment.

Here are the quick tips for Olmesartan Medoxomil 5mg Tablet:

• Always take the tablet as directed by your doctor; do not adjust the dosage without medical advice.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Take the tablet at the same time each day to maintain consistent blood levels.
• Olmesartan works best when used regularly; ensure you never run out of medication.
• Inform your doctor if you have a history of angioedema or liver disease before taking this medication.
• Avoid using potassium supplements or salt substitutes without medical advice while on this medication.
• Store the tablets in their original container, away from moisture and heat.