ORS PLUS Z 500ML LIQUID (LIMOPANI)

Sodium Chloride and Trisodium Citrate Liquid primarily work through their respective ions, which are sodium (Na+) and chloride (Cl-) from sodium chloride, and citrate from trisodium citrate. When administered, sodium chloride helps to restore and maintain the body's electrolyte balance, particularly in cases of fluid loss or electrolyte depletion. It facilitates the movement of fluids across cell membranes, aiding in hydration and maintaining proper fluid distribution in the body. Trisodium citrate, on the other hand, acts as a buffer, helping to regulate the pH of bodily fluids. Citrate ions bind to and remove excess hydrogen ions, thereby increasing the blood's bicarbonate concentration and buffering the blood's pH. This buffering action helps to maintain the body's acid-base balance, particularly in situations where there is a risk of metabolic acidosis.

Sodium chloride:

Solution

The following are the uses of Sodium chloridel, Trisodium citrate Liquid:

• Used for preserving food, especially in pickles, canned vegetables, and cured meats.
• Used for enhancing flavor and acting as a flavoring agent in various food products.
• Used for controlling microbial growth and extending the shelf life of foods.
• Used for regulating acidity or alkalinity in food and beverage production.
• Used for maintaining the texture and stability of processed foods.
• Used for water treatment, ensuring safe drinking water by killing bacteria and purifying water.
• Used for medical purposes, such as intravenous fluids and nasal irrigation solutions.
• Used for laboratory experiments and chemical processes as a common reagent.

In the case of an overdose of Sodium Chloride and Trisodium Citrate Liquid, symptoms may include severe thirst, reduced urine output, nausea, and vomiting. High sodium levels can lead to neurological symptoms like confusion and seizures. In such instances, prompt medical intervention is necessary. Treatment involves managing symptoms and addressing the underlying cause, with the focus on rehydration and restoring electrolyte balance.

In the case of a missed dose of Sodium Chloride and Trisodium Citrate liquid, it is important to administer the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose, it is best to skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one, as this may lead to an overdose. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your dosing schedule.

To take Sodium Chloride and Trisodium Citrate liquid, mix the prescribed amount of the solution with water, stir well, and drink the entire mixture, ensuring you follow the dosage instructions provided by your healthcare provider.

Here are the conditions and situations when Sodium Chloride and Trisodium Citrate Liquid should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to Sodium Chloride or Trisodium Citrate.
• Contraindicated in patients with severe kidney disease or kidney failure.
• Should not be used if the patient is already receiving sodium-restricted treatments.
• Avoid in patients with severe heart failure or fluid retention issues.
• Not recommended for individuals with high blood pressure (hypertension) that is not well controlled.
• Avoid use in patients with swelling due to kidney or heart disease.
• Do not administer if the patient has a condition that causes low sodium levels in the blood (hyponatremia).
• Contraindicated in patients with conditions that cause high sodium levels in the blood (hypernatremia).

The side effects of Sodium Chloride and Trisodium Citrate Liquid may include:

• Nausea and vomiting
• Diarrhea
• Stomach cramps or pain
• Irritation or discomfort at the infusion site
• Swelling or redness at the injection site
• Increased thirst
• Confusion or restlessness
• Muscle weakness or cramps

Following are the precautions and warnings for Sodium Chloride and Trisodium Citrate Liquid:

• Not recommended for individuals with a known allergy to sodium chloride or trisodium citrate.
• Patients with kidney problems should use with caution as it may worsen renal function.
• This medication may cause fluid and electrolyte imbalances, especially in those with pre-existing conditions like heart or liver disease.
• Monitor fluid and electrolyte levels, especially sodium and chloride, during prolonged use.
• Avoid prolonged use without medical supervision to prevent potential complications.
• Do not exceed the recommended dosage, as it may lead to electrolyte disturbances and other adverse effects.
• Consult a healthcare professional before use if you are pregnant, breastfeeding, or have any underlying medical conditions.

Following are the drug interactions for Sodium Chloride and Trisodium Citrate Liquid:

• It can interact with lithium, increasing the risk of lithium toxicity and adverse effects.
• May reduce the effectiveness of medications that lower blood pressure, such as beta-blockers and ACE inhibitors.
• Sodium chloride can decrease the absorption of certain antibiotics, such as tetracyclines, reducing their effectiveness.
• When combined with potassium-sparing diuretics, it may lead to hyperkalemia (high potassium levels).
• May increase the risk of kidney damage when used with nephrotoxic drugs like nonsteroidal anti-inflammatory drugs (NSAIDs).
• Trisodium citrate can increase the effects of anticoagulants, raising the risk of bleeding.
• The effectiveness of certain medications, including quinolone antibiotics, may be reduced due to the alkalizing effect of trisodium citrate.
• Potential interaction with antacids, which can affect the absorption of other medications.

Following are the food interactions for Sodium Chloride and Trisodium Citrate Liquid:

• Avoid excessive salt intake, as Sodium Chloride is a salt compound, and high dietary salt consumption can lead to increased blood pressure and water retention.
• Limit citrus fruits and juices, as Trisodium Citrate can interact with the citric acid in these foods, potentially affecting the balance of citrate in the body.
• Avoid high-potassium foods like bananas, avocados, and spinach if you have kidney issues, as Trisodium Citrate can increase potassium levels.
• Caffeine and Sodium Chloride combination may increase blood pressure temporarily. Monitor intake if you have hypertension.
• Alcohol can increase blood pressure and interact with Sodium Chloride, especially in large amounts, potentially causing dehydration and increased blood pressure.
• Avoid high-sugar foods, as Trisodium Citrate may interact with sugar metabolism, affecting blood sugar levels.
• Ensure adequate fluid intake, especially water, to maintain hydration and support the effects of Sodium Chloride and Trisodium Citrate.

Sodium Chloride and Trisodium Citrate Liquid should be stored in a controlled environment, maintaining a cool temperature between 20°C and 25°C (68°F and 77°F) and avoiding direct exposure to sunlight. Store the liquid in its original container, tightly sealed, to ensure its integrity and prevent contamination. Do not freeze the solution, as this may alter its properties. Always check the expiration date before use, and dispose of any expired or unused liquid responsibly. Proper disposal methods should be followed, avoiding pouring it down the drain or flushing it; instead, consult a pharmacist or healthcare professional for guidance on safe disposal. Keep the liquid out of children's reach to prevent accidental ingestion.

Following are the quick tips for Sodium Chloride and Trisodium Citrate Liquid:

• Consult your healthcare provider for dosage instructions specific to your medical condition.
• Ensure you understand the prescription and clarify any doubts with your pharmacist.
• Administer the liquid as directed, typically via intravenous infusion.
• Monitor fluid intake and output as advised by your healthcare provider.
• Report any signs of fluid overload or electrolyte imbalances immediately.
• Do not mix with other medications unless instructed by a healthcare professional.
• Store the liquid at room temperature, away from direct sunlight.
• Regularly clean and disinfect the infusion site to prevent infection.