Orthram 20g Gel

The mechanism of action of Menthol 3% and Diclofenac diethylamine Gel is attributed to the combination of these two active ingredients. Menthol provides a cooling sensation by activating specific receptors in the skin, leading to a decrease in the perception of pain. It also acts as a counter-irritant, distracting the nervous system from underlying pain signals. Diclofenac diethylamine, a non-steroidal anti-inflammatory drug (NSAID), works by inhibiting the production of prostaglandins, which are involved in pain and inflammation. By blocking the cyclooxygenase (COX) enzymes, diclofenac reduces the synthesis of prostaglandins, thereby decreasing pain, inflammation, and swelling at the site of application. This dual action makes the gel effective in providing localized relief for various musculoskeletal conditions.

Topical Analgesic

Gel

The following are the uses of Menthol 3%, Diclofenac diethylamine Gel:

• Used for relieving pain and inflammation in muscles, joints, and sprains
• Used to provide a cooling sensation and numb mild to moderate pain
• Used for treating muscle aches and stiffness
• Used in reducing joint swelling and stiffness
• Used for soothing backaches, strains, and bruises
• Used to ease minor arthritis pain and discomfort
• Used for temporary relief of minor skin irritations and itching

In the case of an overdose of Menthol 3% and Diclofenac diethylamine Gel, the following symptoms may occur severe skin irritation, burning sensation, and potential gastrointestinal issues. Overuse of Menthol 3% can lead to skin redness, blistering, and allergic reactions. Excessive Diclofenac diethylamine Gel application may cause stomach pain, nausea, and in extreme cases, liver or kidney damage. It is advisable to seek medical advice promptly to address these potential adverse effects.

In the case of a missed dose of Menthol 3%, apply it as soon as you remember, but if it's almost time for your next dose, skip the missed application and resume your regular schedule. For Diclofenac diethylamine Gel, if you forget to apply it, apply it as soon as you remember, but avoid applying extra gel to make up for the missed dose. You can gently massage the gel into the affected area to ensure absorption. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your medication schedule.

To apply Menthol 3%, Diclofenac diethylamine Gel, gently massage the gel onto the affected area, using a thin layer, two to three times a day, or as directed by your healthcare professional, ensuring your hands are clean before and after application.

Here are the conditions and situations when Menthol 3%, Diclofenac diethylamine Gel should not be used:

• Avoid using on open wounds, burns, or severely damaged skin.
• Do not apply to the eyes, mouth, or mucous membranes.
• Not suitable for individuals with a known allergy or sensitivity to menthol, diclofenac, or any of the gel's components.
• Should not be used on skin areas with infections, rashes, or severe inflammation.
• Contraindicated in individuals with a history of asthma or severe respiratory reactions to NSAIDs (non-steroidal anti-inflammatory drugs).
• Avoid using on skin that will be exposed to direct sunlight or UV light immediately after application.
• Not recommended for children below a certain age (check with your healthcare provider).
• Do not use on skin that is already being treated with other topical medications without medical advice.
• Avoid prolonged use on large areas of the body without medical supervision.
• Should not be used if you are allergic to aspirin or other NSAIDs.
• Do not use if you are pregnant or breastfeeding without medical consultation.

The side effects of Menthol 3% and Diclofenac diethylamine Gel may include:

• Skin irritation or redness at the application site
• Burning or stinging sensation
• Itching or rash
• Dryness or peeling of the skin
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• Increased sensitivity to sunlight
• Headache or dizziness
• Gastrointestinal discomfort (including nausea, stomach pain)

Following are the precautions and warnings for Menthol 3%, Diclofenac Diethylamine Gel:

• Avoid contact with eyes, nose, mouth, and other sensitive areas. In case of accidental contact, rinse thoroughly with water.
• Do not apply to broken or irritated skin. Discontinue use if skin irritation or rash occurs.
• Wash your hands thoroughly after applying the gel to avoid accidental transfer to the eyes or other sensitive areas.
• Keep out of reach of children. If a child accidentally ingests the gel, seek immediate medical attention.
• Do not use this medication if you are allergic to diclofenac, aspirin, or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Consult a healthcare professional before use if you have a history of gastrointestinal bleeding, asthma, or liver disease.
• This gel is for external use only. Do not swallow or ingest it.
• Do not apply to large areas of the body or use under occlusive dressings, as this may increase the risk of side effects.

Following are the drug interactions for Menthol 3% and Diclofenac diethylamine Gel:

• Menthol can increase the absorption of other topical medications, potentially enhancing their effects and increasing the risk of adverse reactions.
• Diclofenac may interact with anticoagulants, antiplatelet drugs, and selective serotonin reuptake inhibitors (SSRIs), increasing the risk of bleeding.
• Concomitant use with other nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the likelihood of gastrointestinal side effects and potential kidney problems.
• Topical corticosteroids, when used with Diclofenac, may increase the risk of skin reactions and dermatitis.
• Methotrexate and Diclofenac combination may increase the toxicity of methotrexate.
• Lithium levels may be increased when used with Diclofenac, requiring close monitoring.
• Digoxin levels can be affected by Diclofenac, necessitating regular blood tests.
• Certain diuretics, when combined with Diclofenac, may increase the risk of kidney dysfunction.

Following are the food interactions for Menthol 3%, Diclofenac diethylamine Gel:

• Avoid consuming foods or beverages that are extremely hot or cold while using this gel, as it may cause increased sensitivity and discomfort.
• Spicy foods should be consumed with caution as they can irritate the skin and increase the burning sensation, especially if applied near the mouth or sensitive areas.
• Alcohol-based products like mouthwash or toners might enhance the absorption of Diclofenac, so it's best to consult a doctor for guidance on usage.
• Avoid applying the gel immediately after consuming acidic foods as they can potentially irritate the skin.
• Although not a direct food interaction, smoking can reduce the effectiveness of the gel, so it is advisable to quit or minimize smoking during the treatment period.
• Consuming a diet rich in omega-3 fatty acids and antioxidants can aid in reducing inflammation and support the overall healing process.
• It is generally safe to consume most foods while using Menthol 3% and Diclofenac diethylamine Gel, but always consult your healthcare provider for personalized advice.

Menthol 3%, Diclofenac diethylamine Gel should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing it in high-temperature areas like bathrooms, kitchens, or near heat-emitting appliances. Always adhere to the expiration date on the packaging, and when disposing of the gel, refrain from flushing it down the toilet or pouring it into drains. Consult your pharmacist or healthcare professional for guidance on safe disposal practices. Keep the gel out of children's reach to prevent accidental ingestion.

Following are the quick tips for Menthol 3%, Diclofenac diethylamine Gel:

• Clean and dry the affected area before applying the gel.
• Apply a thin layer of gel and gently massage until absorbed.
• Wash your hands after application to avoid contact with eyes and sensitive areas.
• Avoid applying on broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing.
• Store the gel in a cool, dry place, away from direct sunlight.
• Consult a doctor if symptoms persist or worsen.