OSPEN IMP 250MG TAB (PHENOXYMETHYLPENICILLIN)

Phenoxymethylpenicillin 250mg Tablet, a type of penicillin antibiotic, exerts its bactericidal effect by specifically targeting and inhibiting the synthesis of bacterial cell walls. It achieves this by binding to and inactivating enzymes called transpeptidases, which are crucial for cross-linking peptidoglycan strands, a vital component of the bacterial cell wall. This interference weakens the cell wall, leading to its disintegration and ultimately causing the death of the bacteria. The drug is particularly effective against susceptible gram-positive bacteria, including Streptococcus pneumoniae and non-penicillinase producing staphylococci.

Penicillin antibiotic

Tablet

The following are the uses of Phenoxymethylpenicillin 250mg Tablet:

• Used for treating mild to moderate infections caused by bacteria, such as throat infections, chest infections, and skin or soft tissue infections.
• Used for treating dental infections and preventing infection in patients with rheumatic heart disease or undergoing dental procedures.
• Used for treating ear, nose, and throat infections, particularly in children.
• Used for treating respiratory tract infections like sinusitis and community-acquired pneumonia.
• Used for the prevention of recurrent fever in certain conditions.
• Used for the treatment of bone and joint infections.
• Used for managing infections in patients allergic to other penicillins.

In the case of an overdose of Phenoxymethylpenicillin 250mg Tablets, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Additionally, an overdose may lead to more severe effects, including seizures, kidney damage, and abnormal heart rhythms. It is important to promptly seek medical advice if an overdose is suspected, as early intervention can help manage these potential adverse effects and ensure appropriate treatment is provided to mitigate any harm caused by the excess medication.

In the case of a missed dose of Phenoxymethylpenicillin 250mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may advise you to restart the medication or provide alternative instructions.

To take Phenoxymethylpenicillin 250mg Tablet, swallow the tablet whole with a full glass of water, following the prescribed dosage instructions provided by your healthcare professional, typically taken 4 times a day, or as directed by your doctor.

Here are the situations when Phenoxymethylpenicillin 250mg Tablet should not be used:

• Avoid if you are allergic to penicillin or any other ingredients in the medication.
• Do not use if you have a history of severe allergic reactions to any beta-lactam antibiotics.
• Contraindicated in individuals with a known history of severe or life-threatening liver problems.
• Should not be used if you have infectious mononucleosis.
• Avoid using this medication if you have a severe kidney disease or condition.
• Not suitable for individuals with a history of gastrointestinal diseases or conditions that could affect drug absorption.
• Do not use if you have a known blood disorder or a family history of glucose-6-phosphate dehydrogenase (G6PD) deficiency.

The side effects of Phenoxymethylpenicillin 250mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Skin rash or itching
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• White patches or sores inside the mouth or on the lips
• Vaginal itching or discharge
• Joint pain or swelling
• Unusual bleeding or bruising

Here are the precautions and warnings for Phenoxymethylpenicillin 250mg Tablet:

• This medication should not be taken if you have a known allergy to penicillin or any other ingredients in the tablet.
• Patients with a history of asthma or other allergic conditions should exercise caution and consult a healthcare professional before use.
• Inform your doctor if you have any kidney or liver problems as dosage adjustments might be necessary.
• It is important to complete the full course of treatment, even if you feel better before the medication is finished.
• Avoid consuming alcohol while taking this medication as it may reduce the effectiveness of the antibiotic.
• If you are pregnant, breastfeeding, or planning to become pregnant, consult your doctor before taking this medication.
• Some medications may interact with Phenoxymethylpenicillin, so inform your healthcare provider about all the medicines you are currently taking.

Following are the drug interactions for Phenoxymethylpenicillin 250mg Tablet:

• Probenecid can reduce the excretion of penicillin, increasing its blood levels and risk of side effects.
• Phenoxymethylpenicillin may decrease the effectiveness of oral contraceptives, so alternative birth control methods are recommended.
• Concurrent use with methotrexate can increase methotrexate levels, potentially requiring dose adjustments.
• It may reduce the effectiveness of live vaccines, so vaccination schedules should be adjusted accordingly.
• May interact with other antibiotics like tetracyclines, potentially reducing their efficacy.
• Blood thinners like warfarin should be monitored closely as penicillin can affect their action.
• Certain uricosuric agents, when combined with penicillin, may increase the risk of skin reactions.

Following are the food interactions for Phenoxymethylpenicillin 250mg Tablet:

• Avoid consuming large amounts of food or beverages containing high levels of tyramine (aged cheeses, cured meats, fermented foods) as they can interact with the medication and cause a dangerous increase in blood pressure.
• Grapefruit juice should be consumed cautiously as it may affect the breakdown of the drug, potentially leading to increased levels in the body.
• Alcohol may reduce the absorption of Phenoxymethylpenicillin, so it's best to avoid or limit alcohol consumption during the course of treatment.
• Maintain a diet rich in vitamin K (leafy greens, broccoli, liver) as Phenoxymethylpenicillin can sometimes interfere with vitamin K absorption, which is crucial for blood clotting.
• Probiotics and fermented foods containing live cultures (yogurt, kefir, sauerkraut) can help restore healthy gut bacteria that may be disrupted by the antibiotic.
• Ensure adequate fluid intake to maintain hydration and support the body's natural detoxification processes.
• There are no specific food restrictions, but maintaining a balanced diet is essential to support overall health during antibiotic treatment.
• Always follow the dosage and dietary instructions provided by your healthcare professional for the best treatment outcomes.

Phenoxymethylpenicillin 250mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to store them in bathrooms or near heat sources like ovens or heaters, as temperature fluctuations can impact their effectiveness. Proper disposal of unused or expired tablets is essential; do not flush them or pour them down the drain. Consult a pharmacist or healthcare professional for guidance on appropriate disposal methods. Always keep medications securely stored, out of the reach of children, to prevent accidental consumption.

Following are the quick tips for Phenoxymethylpenicillin 250mg Tablet:

• Ensure you complete the full course of medication as prescribed by your doctor.
• Take the tablet with a full glass of water for easy swallowing.
• Maintain a consistent schedule for taking the medicine, preferably at the same time each day.
• If you experience stomach irritation, consider taking the tablet with food to minimize discomfort.
• Avoid crushing or chewing the tablet; swallow it whole for best results.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Regularly monitor your condition and inform your doctor of any persistent or worsening symptoms.