OXAZE TAB

Oxcarbazepine, the active ingredient in the 100mg tablet, primarily exerts its therapeutic effects by blocking voltage-sensitive sodium channels, which are crucial for the generation and propagation of action potentials in neurons. This mechanism is thought to stabilize hyperexcitable neural membranes, inhibiting the repetitive firing of neurons and reducing the propagation of synaptic impulses. As a result, oxcarbazepine helps decrease the release of glutamate, an excitatory neurotransmitter, and enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, thereby reducing neuronal excitability and stabilizing abnormal electrical activity in the brain. This action is particularly effective in preventing seizures, making oxcarbazepine a valuable medication in the management of certain types of epilepsy and other conditions characterized by excessive neuronal activity.

Anticonvulsant

Tablet

The following are the uses of Oxcarbazepine 100mg Tablet:

• Used for controlling and preventing seizures in adults and children.
• Used for treating partial seizures, both as monotherapy and as add-on therapy.
• Used to manage and stabilize mood disorders, particularly in bipolar disorder.
• Used to alleviate nerve pain associated with conditions like trigeminal neuralgia.
• Used to reduce the frequency and severity of migraine attacks.
• Used in the treatment of certain anxiety disorders, aiding in symptom management.
• Used to support the treatment of alcohol dependence, helping with withdrawal symptoms.

In the case of an overdose of Oxcarbazepine 100mg Tablets, individuals may experience symptoms such as dizziness, blurred vision, and gastrointestinal issues like nausea and vomiting. The severity of the overdose can vary depending on the amount ingested. It is crucial to seek medical advice promptly and provide the necessary information regarding the dosage and timing of the overdose. Quick action can help mitigate potential health risks and ensure appropriate treatment measures are taken to address the situation effectively.

In the case of a missed dose of Oxcarbazepine 100mg Tablet, it is important to take the missed dose as soon as you remember, but only if the next scheduled dose is not too close. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is recommended to set a reminder or use a pill organizer to help you remember your medication schedule and minimize the chances of missing a dose.

To take Oxcarbazepine 100mg Tablets, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically starting with a lower dose and gradually increasing as directed.

Following are the conditions when Oxcarbazepine 100mg Tablet should not be taken:

• Should not be used in individuals with a known allergy to Oxcarbazepine or any of the related medications.
• Not suitable for people with a rare genetic blood disorder called porphyria.
• Contraindicated in patients with a history of bone marrow suppression.
• Should not be used if you have a condition called progressive atrial enlargement.
• Avoid using this medication if you have a heart condition called sinus bradycardia.
• Not recommended for individuals with a history of second or third-degree atrioventricular (AV) block.
• Contraindicated in patients with a history of severe heart failure.

The side effects of Oxcarbazepine 100mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or drowsiness
• Nausea and vomiting
• Headache
• Skin rashes or itching
• Blurred or double vision
• Balance or coordination problems
• Dry mouth

Following are the precautions and warnings for Oxcarbazepine 100mg Tablet:

• Do not start or stop this medication without consulting your doctor, as sudden changes can cause seizures.
• Regular blood tests are required to monitor liver function and blood cell counts while taking this medication.
• Oxcarbazepine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
• Inform your doctor if you have a history of depression, suicidal thoughts, or any other mental health disorders before taking this medication.
• Alcohol consumption should be avoided or limited while on this medication, as it can increase the risk of side effects.
• This medication may cause hyponatremia (low sodium levels in the blood); symptoms include headache, confusion, and fatigue.
• Patients with a history of kidney or liver disease should use this medication with caution and under medical supervision.
• Pregnant and breastfeeding women should consult their doctor before taking Oxcarbazepine, as it may have potential risks to the fetus or infant.

Following are the drug interactions for Oxcarbazepine 100mg Tablet:

• Carbamazepine and phenytoin can reduce oxcarbazepine levels, potentially decreasing its effectiveness.
• Oxcarbazepine may increase levels of certain antiepileptic drugs like lamotrigine, phenytoin, and valproic acid, requiring dose adjustments.
• Concomitant use with phenobarbital can decrease oxcarbazepine levels, reducing its efficacy.
• The effect of oxcarbazepine may be reduced by oral contraceptives, potentially affecting seizure control.
• It can decrease the effectiveness of hormonal contraceptives, requiring alternative birth control methods.
• Oxcarbazepine may increase blood levels of lithium, requiring close monitoring of lithium levels.
• Caution is advised when combining with other CNS depressants, as it may enhance sedation and impair breathing.

Following are the food interactions for Oxcarbazepine 100mg Tablet:

• Alcohol consumption should be avoided as it may increase the risk of side effects, including dizziness, drowsiness, and impaired coordination.
• Grapefruit and grapefruit juice are to be avoided as they can increase the levels of Oxcarbazepine in the blood, potentially leading to increased side effects.
• High-fat meals can slow down the absorption of Oxcarbazepine, leading to a delay in reaching the desired therapeutic effect.
• Avoid caffeine-rich foods and beverages as they may increase the frequency of seizures in some patients.
• Sodium intake should be monitored as Oxcarbazepine can cause sodium retention, which may be problematic for individuals with heart or kidney issues.
• Avoid foods rich in tyramine (aged cheeses, cured meats) as Oxcarbazepine may interact, leading to a spike in blood pressure.
• It is generally recommended to maintain a balanced diet and drink plenty of fluids to minimize potential side effects.
• Always consult your healthcare provider for personalized advice regarding dietary restrictions and interactions.

Oxcarbazepine 100mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to environmental factors. Always check the expiration date before taking any medication, and properly dispose of expired or unused tablets. Do not flush or pour them down the drain; consult your pharmacist for guidance on appropriate disposal methods. Remember to keep all medications, including Oxcarbazepine, out of the sight and reach of children to ensure their safety and prevent accidental consumption.

Following are the quick tips for Oxcarbazepine 100mg Tablet:

• Always take the medication as directed by your doctor; do not adjust the dosage without medical advice.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Oxcarbazepine can be taken with or without food, but be consistent with your routine.
• Maintain a consistent schedule by taking the tablet at the same time each day.
• If you experience side effects like dizziness, avoid driving or operating machinery.
• Regular blood tests may be required to monitor your progress and adjust dosage.
• Store the medication at room temperature, away from moisture and light.