Oxetin (25mg) 100 Capsules

Fluoxetine 25mg capsules primarily work by selectively inhibiting the reuptake of serotonin in the brain. Serotonin is a neurotransmitter that plays a crucial role in regulating mood, emotions, and various physiological processes. Fluoxetine blocks the serotonin transporter (SERT) protein, leading to increased availability of serotonin in the synaptic cleft. This elevation in serotonin levels enhances serotonergic neurotransmission, which is believed to contribute to the therapeutic effects of fluoxetine. By modulating serotonin signaling, fluoxetine helps to alleviate symptoms of depression, anxiety, and certain other psychiatric disorders, although the exact neurobiological mechanisms underlying its efficacy are still being studied.

Fluoxetine 25mg

Antidepressant, SSRI (Selective Serotonin Reuptake Inhibitor).

Capsule

The following are the uses of Fluoxetine 25mg Capsule:

• Used for treating major depressive disorder, helping to alleviate symptoms and improve mood.
• Used for managing obsessive-compulsive disorder (OCD) by reducing intrusive thoughts and compulsive behaviors.
• Used for addressing panic disorder, aiming to decrease the frequency and intensity of panic attacks.
• Used for certain eating disorders, such as bulimia nervosa, to assist in regulating eating patterns.
• Used for alleviating premenstrual dysphoric disorder (PMDD) symptoms, providing relief during the luteal phase of the menstrual cycle.
• Used for managing conditions like depression and anxiety in patients with co-occurring disorders.
• Used for maintaining treatment gains and preventing relapse in patients who have responded well to initial therapy.

In the case of an overdose of Fluoxetine 25mg Capsules, symptoms may include nausea, vomiting, seizures, irregular heartbeat, and even loss of consciousness. Prompt medical attention is necessary, and the individual should be monitored for any signs of serotonin syndrome, a potentially life-threatening condition. It is crucial to seek emergency help if an overdose is suspected, as quick action can prevent severe complications. Medical professionals will provide the necessary treatment and support to manage the overdose effectively.

In the case of a missed dose of Fluoxetine 25mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance on how to safely adjust your dosing schedule. It is essential to maintain consistency with this medication, but if you frequently miss doses, inform your doctor, as they may provide alternative solutions.

To take Fluoxetine 25mg Capsule, swallow the capsule whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, and continue taking it daily at the same time for the prescribed duration.

Here are the conditions or situations when Fluoxetine 25mg Capsule should not be taken:

• Should not be used in patients with a known allergy or hypersensitivity to Fluoxetine or other selective serotonin reuptake inhibitors (SSRIs).
• Contraindicated in individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Not suitable for patients currently taking monoamine oxidase inhibitors (MAOIs) or who have taken MAOIs within the last 14 days.
• Should be avoided in patients with glaucoma, as it may increase intraocular pressure.
• Not recommended for individuals with a history of bleeding disorders or those on blood-thinning medications.
• Contraindicated in patients with a history of serotonin syndrome or those taking other medications that increase serotonin levels.
• Should be used with caution in patients with diabetes, as it may affect blood glucose levels.
• Not suitable for individuals with severe kidney or liver impairment.
• Should be avoided in patients with a history of cardiovascular disease or those with a family history of cardiac arrhythmias.
• Contraindicated in patients with a history of manic episodes or bipolar disorder.

The side effects of Fluoxetine 25mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Headaches
• Insomnia (difficulty sleeping)
• Dizziness
• Anxiety or nervousness
• Fatigue and weakness
• Sexual dysfunction

Following are the precautions and warnings for Fluoxetine 25mg Capsule:

• This medication should not be started in patients who are being treated with MAO inhibitors or within 14 days of stopping such treatment due to the risk of serotonin syndrome.
• Fluoxetine may increase the risk of suicidal thoughts and behavior in children, adolescents, and young adults; close monitoring is essential during treatment.
• Patients with a history of seizures or conditions that lower the seizure threshold should be closely monitored, as Fluoxetine may lower the seizure threshold.
• Not recommended for use in patients with severe liver disease, as it is extensively metabolized in the liver.
• Patients with diabetes should be aware that Fluoxetine may alter glucose control.
• Electrolyte and ECG changes have been reported with Fluoxetine use; monitoring is advised, especially in patients with cardiac disease.
• May cause photosensitivity; patients should be advised to limit sun exposure and use protective measures.

Following are the drug interactions for Fluoxetine 25mg Capsule:

• Concomitant use with other serotonergic agents like tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, St. John's Wort, can increase serotonin levels, leading to serotonin syndrome.
• Monoamine oxidase inhibitors (MAOIs) interaction is contraindicated, avoid within 14 days of stopping Fluoxetine.
• May increase bleeding risk with anticoagulants like warfarin, heparin, or antiplatelet drugs.
• Central nervous system depressants (e.g., benzodiazepines, opioids) may have enhanced effects, leading to increased sedation.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of gastrointestinal bleeding.
• Fluoxetine may elevate levels of drugs metabolized by CYP450 enzymes, including phenytoin, diazepam, and tricyclic antidepressants.
• May decrease plasma levels of antipsychotics (e.g., haloperidol, clozapine).

Following are the food interactions for Fluoxetine 25mg Capsule:

• Avoid consuming alcohol as it can increase the risk of side effects and may cause excessive drowsiness and sedation.
• Grapefruit and grapefruit juice should be consumed with caution as they may increase the levels of Fluoxetine in the blood, potentially leading to higher side effects.
• Consuming high-fat meals may delay the absorption of Fluoxetine, but it does not significantly reduce its effectiveness.
• Avoid foods rich in tyramine, such as aged cheese, cured meats, and fermented foods, as they can interact with Fluoxetine and increase blood pressure.
• Avoid herbal supplements like St. John's Wort, as it can reduce the effectiveness of Fluoxetine.
• Do not consume energy drinks or excessive amounts of caffeine as they may enhance the stimulant effects of Fluoxetine.
• Always follow the dosage instructions provided by your healthcare professional to minimize the risk of food interactions.

Fluoxetine 25mg Capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the capsules in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Do not expose the medication to extreme temperatures or store it in the bathroom or kitchen, as heat and humidity can degrade the capsules. Dispose of any unused or expired medication responsibly; do not flush or pour it down the drain. Contact your pharmacist or healthcare provider for guidance on proper disposal methods, and keep the medication safely out of children's reach to prevent accidental consumption. It is crucial to handle and store Fluoxetine capsules with care to maintain their effectiveness and ensure safety.

Following are the quick tips for Fluoxetine 25mg Capsule:

• Start with a low dose and gradually increase as directed by your doctor.
• Swallow the capsule whole with a full glass of water, preferably in the morning.
• Avoid crushing or chewing the capsule to prevent a bitter taste.
• Do not take with high-fat meals as it may affect absorption.
• Wait at least 5-7 days between dose adjustments to assess the effects.
• Regularly monitor your mood and any changes in behavior while on this medication.
• Store in a cool, dry place, away from direct sunlight.