Ozip Plus (6/25mg) 30 Capsules

Fluoxetine, a component of the Fluoxetine 25mg, Olanzapine 6mg Capsule, primarily acts as a selective serotonin reuptake inhibitor (SSRI). It increases serotonin levels in the brain by blocking its reabsorption into the presynaptic neuron, enhancing serotonin signaling. This mechanism is thought to contribute to its antidepressant, anxiolytic, and mood-stabilizing effects. Olanzapine, the other component, is an atypical antipsychotic that exerts its effects through multiple pathways. It antagonizes dopamine receptors, particularly D2 receptors, in the mesolimbic pathway, which is believed to underlie its antipsychotic properties. Olanzapine also blocks specific serotonin receptors, such as 5-HT2A and 5-HT2C, and exhibits high affinity for 5-HT1A receptors, potentially contributing to its antidepressant and mood-regulating actions. This combination of fluoxetine and olanzapine in the capsule aims to address both mood and psychotic symptoms by targeting serotonin and dopamine neurotransmission.

Fluoxetine 25mg, Olanzapine 6mg

Antidepressant/Antipsychotic combination.

Capsule

The following are the uses of Fluoxetine 25mg, Olanzapine 6mg Capsule:

• Used for treating Major Depressive Disorder, helping to elevate mood and alleviate symptoms of depression.
• Used to manage Bipolar Depression, aiming to stabilize mood and reduce depressive episodes.
• Used in the treatment of Obsessive-Compulsive Disorder (OCD) to reduce compulsive behaviors and anxiety.
• Effective for Bulimia Nervosa, helping to reduce binge-eating and purging behaviors.
• Used for managing Panic Disorder, providing relief from panic attacks and associated anxiety.
• Can be utilized for Premenstrual Dysphoric Disorder (PMDD) to ease emotional and physical symptoms.
• Used in combination with Olanzapine for Schizophrenia, aiming to control symptoms and prevent relapses.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Olanzapine 6mg-
• Depression • initial- 2.5mg-5mg/day divided into 2-3 doses
• Depression • maintenance- 5-10mg/day divided into 2-3 doses
• Anxiety • initial- 2.5mg-3mg/day divided into 2 doses
• Anxiety • maintenance- 5-7.5mg/day divided into 2 doses
• Schizophrenia • initial- 10-15mg/day divided into 2 doses
• Schizophrenia • maintenance- 15-30mg/day divided into 2 doses
• Fluoxetine 25mg-
• Depression • adults- 20-80mg/day in divided doses
• Anxiety • adults- 20-60mg/day in divided doses

In the case of an overdose of Fluoxetine 25mg and Olanzapine 6mg capsules, it is important to seek medical advice promptly. Symptoms may include nausea, vomiting, seizures, rapid heartbeat, and changes in blood pressure. Medical professionals should be contacted immediately to provide guidance and determine the necessary treatment. Prompt action can help manage potential adverse effects and ensure the well-being of the individual who has overdosed.

In the case of a missed dose of Fluoxetine 25mg, it is recommended to take the missed dose as soon as you remember, but if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. For Olanzapine 6mg Capsule, if a dose is missed, take it as soon as possible, but if it's almost time for the next dose, skip the missed dose and continue with your regular dosing regimen. It is important to maintain a consistent medication routine, but if you frequently miss doses, consult your healthcare provider for guidance on how to manage missed doses effectively.

To take the Fluoxetine 25mg and Olanzapine 6mg Capsule, swallow the capsule whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, ensuring you follow the prescribed dosage and treatment duration.

Following are the conditions or circumstances when Fluoxetine 25mg, Olanzapine 6mg Capsule should not be taken:

• Do not take if you are allergic to Fluoxetine, Olanzapine, or similar medications.
• Avoid if you have recently taken a Monoamine Oxidase Inhibitor (MAOI) or are currently taking one.
• Not suitable for individuals with a history of liver problems or liver disease.
• Should not be used in patients with narrow-angle glaucoma.
• Contraindicated in individuals with a history of seizures or epilepsy.
• Do not use if you have diabetes, as Olanzapine may affect blood sugar levels.
• Not recommended for patients with heart problems or low blood potassium levels.

The side effects of Fluoxetine 25mg and Olanzapine 6mg Capsule may include:

• Nausea and vomiting
• Dizziness or lightheadedness
• Dry mouth
• Increased appetite and weight gain
• Fatigue and drowsiness
• Restlessness or agitation
• Blurred vision
• Muscle stiffness or tremors

Following are the precautions and warnings for Fluoxetine 25mg, Olanzapine 6mg Capsule:

• Not suitable for individuals with a known allergy to Fluoxetine, Olanzapine, or any of the capsule's components.
• Patients with a history of liver or kidney problems should use with caution, as dosage adjustments may be necessary.
• Exercise caution when combining with other medications, especially those affecting the central nervous system, as it may increase the risk of side effects.
• Avoid alcohol consumption while taking this medication as it can intensify drowsiness and other side effects.
• Patients should not drive or operate heavy machinery if they experience severe drowsiness or dizziness.
• Consult a healthcare professional before use during pregnancy or breastfeeding, as it may pose risks to the fetus or infant.
• Keep out of reach of children and store in a cool, dry place.
• Discontinue use and seek medical attention if severe side effects occur, such as persistent nausea, seizures, or abnormal heart rhythms.

Following are the drug interactions for Fluoxetine 25mg, Olanzapine 6mg Capsule:

• Concomitant use with other antipsychotics or CNS depressants can lead to increased sedation and respiratory depression.
• Fluoxetine may increase Olanzapine levels, requiring dosage adjustments.
• The combination may enhance anticholinergic effects, leading to dry mouth, constipation, and blurred vision.
• Alcohol may intensify the sedative effects, impairing cognitive and motor skills.
• Drugs metabolized by CYP450 enzymes, especially CYP2D6 and CYP1A2, may have altered concentrations when taken with Fluoxetine.
• Medications that lower the seizure threshold, such as tramadol or bupropion, may increase the risk of seizures.
• Antihypertensive medications may have reduced effectiveness due to the antipsychotic properties of Olanzapine.

Following are the food interactions for Fluoxetine 25mg, Olanzapine 6mg Capsule:

• Avoid consuming alcohol while on this medication, as it can increase the risk of side effects and may also impact the effectiveness of Fluoxetine.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Fluoxetine, potentially leading to increased blood levels and side effects.
• Caffeine intake should be monitored as it can interact with Olanzapine, potentially increasing its sedative effects.
• Avoid high-fat meals as they may delay the absorption of Fluoxetine, affecting its effectiveness.
• Avoid eating large quantities of cheese, as it may contain high levels of tyramine, which can interact with Fluoxetine and lead to elevated blood pressure.
• Do not consume herbal supplements like St. John's Wort, as it can reduce the efficacy of Fluoxetine.
• Ensure a balanced diet as Olanzapine may increase appetite and lead to weight gain.
• Consult your healthcare provider for personalized dietary advice and any specific food restrictions related to this medication.

Fluoxetine 25mg, Olanzapine 6mg Capsule should be stored in a cool and dry place, preferably at room temperature (around 25°C). Keep the capsules in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Avoid exposure to direct sunlight, moisture, or extreme temperatures. It is crucial to store the medication away from children and pets to prevent accidental ingestion. When disposing of unused or expired capsules, do not flush them down the toilet or discard them into the trash. Instead, follow local guidelines for pharmaceutical waste disposal, or consult your pharmacist for safe disposal options.

Following are the quick tips for Fluoxetine 25mg, Olanzapine 6mg Capsule:

• Take the capsule at the same time each day as directed by your doctor.
• Swallow the capsule whole with a full glass of water; do not crush, chew, or open it.
• You can take it with or without food, but be consistent with your choice.
• If you experience difficulty swallowing, consider taking it with applesauce as per your doctor's advice.
• Do not stop taking the medication abruptly; consult your doctor for tapering instructions.
• Store the capsules in a cool, dry place, away from direct sunlight.
• Inform your doctor about all the medications and supplements you are taking to avoid potential interactions.

When taking Olanzapine and Fluoxetine, it is crucial to ensure that these drugs are effective and safe for your body. Hence, periodic laboratory tests are essential to monitor your health. These tests include a complete blood count (CBC) to check the overall health of your blood cells, especially your red and white blood cells and platelets. Blood chemistry tests are also necessary to monitor the levels of glucose, sodium, potassium, and calcium in your blood, as these levels could be altered by these drugs. Additionally, it is vital to assess your cholesterol levels using a lipid panel, which is crucial for your overall health and especially when taking Olanzapine. This medication can increase the risk of weight gain and high cholesterol.Measuring vitamin D levels in your blood is also essential since Olanzapine and Fluoxetine can affect vitamin D metabolism. Thyroid functions should be tested as well, as these medications can impact thyroid function, and routine monitoring can help detect any issues in advance. Frequent urine drug tests may be required to monitor misuse, overuse, or signs of addiction to ensure that your treatment plan is effective and safe for you. These lab tests should be conducted under medical supervision, and your dosage may be adjusted or alternative treatment options offered if any issues arise based on the results.